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LXR signaling controls homeostatic dendritic cell maturation
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PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance
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Laboratory mice with a wild microbiota generate strong allergic immune responses
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Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion
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Pannexin 1 drives efficient epithelial repair after tissue injury
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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141
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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
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Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3(+) CD8(+) T-regs
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Welcoming c-MAF to the macrophage transcription factor VAM-ily
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Single-cell analysis pinpoints distinct populations of cytotoxic CD4(+) T cells and an IL-10(+)CD109(+)TH2 cell population in nasal polyps