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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141
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- Journal Article
- A1
- open access
Pannexin 1 drives efficient epithelial repair after tissue injury
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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
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Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3(+) CD8(+) T-regs
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Welcoming c-MAF to the macrophage transcription factor VAM-ily
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- Journal Article
- A1
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X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19
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- Journal Article
- A1
- open access
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
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Single-cell analysis pinpoints distinct populations of cytotoxic CD4(+) T cells and an IL-10(+)CD109(+)TH2 cell population in nasal polyps
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Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages
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Lin28b controls a neonatal to adult switch in B cell positive selection