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- Journal Article
- A1
- open access
Whole slide imaging-based prediction of TP53 mutations identifies an aggressive disease phenotype in prostate cancer
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- Journal Article
- A1
- open access
Quantification of neoantigen-mediated immunoediting in cancer evolution : letter
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Immunotherapeutic targeting and PET imaging of DLL3 in small-cell neuroendocrine prostate cancer
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Heterogeneity of CAFfeinated tumors : sweet targeting perspectives
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- Journal Article
- A1
- open access
Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages
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Adherence to and patient satisfaction with the combination therapy of exemestane and everolimus in postmenopausal women with HR+ HER2- advanced breast cancer : results from the IPSOC-mamma study
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Loss-of-function mutations in TRAF7 and KLF4 cooperatively activate RAS-like GTPase signaling and promote meningioma development
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The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype
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Fatty acid binding protein 7 regulates beige fat-like differentiation of breast cancer cells and thermogenesis
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Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness
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Splenic hematopoietic and stromal cells in cancer progression
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A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors
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Global alteration of CTCF binding in the cancer genome
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Associations of aspirin, non-aspirin NSAIDs, statins, and metformin with risk of biliary tract cancer : a Swedish population-based cohort study
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PHF6loss drives IL7R oncogene addiction in TLX1 driven T-ALL
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastomas
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Is a single driver gene mutation sufficient for monitoring early response in advanced colorectal cancer
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Circulating tumor DNA detects early response to regorafenib in advanced colorectal cancer
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A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic leukemias in vivo
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Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments
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Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
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Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN
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A transcriptome-wide association study among 97,898 women to identify candidate susceptibility genes for epithelial ovarian cancer risk
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The THINK clinical trial : preliminary evidence of clinical activity of NKG2D chimeric antigen receptor T cell therapy (CYAD-01) in acute myeloid leukemia
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Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation
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BELIS : safety and tolerability of at home administration of trastuzumab (Herceptin (R)) subcutaneous for the treatment of patients with HER2-positive early breast cancer
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An accessible proteogenomics informatics resource for cancer researchers
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BRCA2 hypomorphic missense variants confer moderate risks of breast cancer
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The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
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Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia
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Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs
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M-CSF and GM-CSF receptor signaling differentially regulate monocyte maturation and macrophage polarization in the tumor microenvironment
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BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
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Lenalidomide stabilizes the erythropoietin receptor by inhibiting the E3 ubiquitin ligase RNF41
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Tissue factor induced by epithelial-mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells
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BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
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Selective cross-cohort discovery of transcriptional mechanisms presiding over high-risk neuroblastoma subtype state maintenance
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Eradication of neuroblastoma by suppressing the expression of a single long noncoding RNA
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Exhaled breath as diagnostic tool for malignant pleural mesothelioma
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Depleting MET-expressing tumor cells by ADCC provides a therapeutic advantage over inhibiting HGF/MET signaling
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TALEN mediated mutation of apc and β-catenin in Xenopus tropicalis as powerful models for Wnt driven cancer and Familial Adenomatous Polyposis (FAP)
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Targeting super-enhancer induced gene expression with the novel BRD4 inhibitor OTX015 in preclinical models of MYCN-amplified neuroblastoma
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Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations
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Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling
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Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties
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Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma
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Magnetic resonance spectroscopy based total choline estimation : does it have a role in the differentiation of grade II breast cancers into high and low risk groups?
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The CpG island methylator phenotype: what's in a name?
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An epigenomic next-generation sequencing approach to identify predictive markers for PARP inhibitor response in breast cancer cells
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IFNβ produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response
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Proinflammatory characteristics of SMAC/DIABLO-induced cell death in antitumor therapy
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Preclinical evaluation of TriMix and antigen mRNA-based anti-tumor therapy
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A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma
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- Conference Paper
- C3
- open access
Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression
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Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas
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Expression of LIGHT/TNFSF14 combined with vaccination against human papillomavirus type 16 E7 induces significant tumor regression
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Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development
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Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction
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An ex(o)citing machinery for invasive tumor growth
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Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells
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An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity
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Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells
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Central role of c-Myc during malignant conversion in human hepatocarcinogenesis
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Glomus tumors in neurofibromatosis type 1: genetic, functional, and clinical evidence of a novel association (vol 69, pg 7393, 2009)
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Glomus tumors in neurofibromatosis type 1: genetic, functional, and clinical evidence of a novel association
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The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha
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Fine tuning of the Van Nuys prognostic index (VNPI) 2003 by using genomic grade index (GGI): a new tool for ductal carcinoma in situ (DCIS).
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Biomarkers ER, PR, HER-2 En topoisomerase II alpha in correlation with response to neoadjuvant chemotherapy for primary breast cancer
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Gynaecological Assessment of Postmenopausal Women with an Asymptomatic Thickened Endometrium While on Tamoxifen: Results from a Double Blind Randomized Controlled Trial Comparing Continuation of Tamoxifen and Anastrozole
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Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73 alpha tumor suppressor
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Novel and highly recurrent chromosomal alterations in Sezary syndrome
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Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells
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Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer
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Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25
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Genome-wide promoter analysis uncovers portions of the cancer methylome
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Manipulation of [C-11]-5-hydroxytryptophan and 6-[F-18]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells
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The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor-/progesterone receptor-/HER-2-breast carcinomas
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Identification of epigenetically silenced genes in tumor endothelial cells
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A novel ovarian xenografting model to characterize the impact of chemotherapy agents on human primordial follicle reserve
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Protection of zinc against tumor necrosis factor-induced lethal inflammation depends on heat shock protein 70 and allows safe antitumor therapy
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Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma
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E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
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Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappa B gene expression by soy isoflavones does not require estrogenic activity
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Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric G alpha/G beta gamma protein complex
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P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma
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STAT3, TFF3, VEGFR in colon cancer cells (vol 65, pg 165, 2005)
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The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
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Expression and nuclear location of the transcriptional repressor kaiso is regulated by the tumor microenvironment
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P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells
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Loss of vascular endothelial growth factor A activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation
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The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
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Aberrant splicing in several human tumors in the tumor suppressor genes neurofibromatosis type 1, neurofibromatosis type 2, and tuberous sclerosis 2.
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The new Sulindac derivative IND 12 reverses Ras-induced cell transformation
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The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy
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An overview of the MAGE gene family with the identification of all human members of the family
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A novel N-ras mutation in malignant melanoma is associated with excellent prognosis
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Two novel 14-epi-analogues of 1,25-dihydroxyvitamin D-3 inhibit the growth of human breast cancer cells in vitro and in vivo
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Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa.
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ß-Catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas.
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Characteristic pattern of chromosomal gains and losses in Merkel cell carcinoma detected by comparative genomic hybridization