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The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature
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Prenatal treprostinil improves pulmonary arteriolar hypermuscularization in the rabbit model of congenital diaphragmatic hernia
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Structure-function relationship of new peptides activating human Nav1.1
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Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets
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Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy
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An AKT2-specific nanobody that targets the hydrophobic motif induces cell cycle arrest, autophagy and loss of focal adhesions in MDA-MB-231 cells
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Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells
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Oleuropein protects L-02 cells against H2O2-induced oxidative stress by increasing SOD1, GPx1 and CAT expression
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The need to develop centers for environmental oncology
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Biomonitoring for genotoxic effects has a low sensitivity in terms of cancer risks associated with lifelong exposures starting in utero