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Reply to Lipworth and Chan
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- Miscellaneous
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Is efficacy of tezepelumab independent of severe asthma phenotype?
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- Miscellaneous
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Adequate antimicrobial dosing in critically ill patients receiving extracorporeal membrane oxygenation : where to go from here?
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- Journal Article
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Causal inference and VAP-attributable mortality in COVID-19 : on painting bulls-eyes and dotting i’s
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- Journal Article
- A1
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Antiviral responses of tissue-resident CD49a+ lung natural killer cells are dysregulated in chronic obstructive pulmonary disease
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Risk stratifying interstitial lung abnormalities to guide early diagnosis interstitial lung diseases
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- Miscellaneous
- open access
What is frailty?
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- Journal Article
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Global Initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
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- Journal Article
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Pulmonary function and blood DNA methylation a multiancestry epigenome-wide association meta-analysis
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Rapid and sustained effects of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps : analysis of the SINUS-24 and SINUS-52 phase 3 trails
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9, supplement S). p.A1345-A1345 -
Dupilumab provides early and durable improvement of symptoms in patients with chronic rhinosinusitis with nasal polyps : results from the SINUS-24 and SINUS-52 phase 3 trials
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9S). p.A1341-A1341 -
Dupilumab efficacy and safety in children with uncontrolled, moderate-to-severe asthma : the phase 3 VOYAGE study
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9S). p.A1204-A1204 -
Association between dupilumab effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS-24 and SINUS-52 trials
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9S). p.A1343-A1343 -
Efficacy of dupilumab in patients with chronic rhinosinusitis with nasal polyps and allergic rhinitis
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9S). p.A1340-A1340 -
Dupilumab shows sustained efficacy and improvements in asthma control and health-related quality of life in patients with moderate-to-severe asthma : liberty asthma traverse
(2021) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. In American Journal of Respiratory and Critical Care Medicine 203(9S). p.A1452-A1452 -
- Journal Article
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Necroptosis signalling promotes inflammation, airway remodelling and emphysema in COPD
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- Conference Paper
- C3
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Baseline characteristics of patients with chronic rhinosinusitis with nasal polyps and comorbid asthma from the pooled populations of the SINUS-24 and SINUS-52 Dupilumab phase 3 trials
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- Conference Paper
- C3
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Aspiration risks factors, microbiology and empiric antibiotics for patients hospitalized with community acquired pneumonia
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Age-dependent loss of small airways during natural lung aging
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- Journal Article
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Inhaled corticosteroids and COVID-19 reply
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- Miscellaneous
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COVID-19, asthma, and inhaled corticosteroids : another beneficial effect of inhaled corticosteroids?
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- Journal Article
- A1
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Respiratory Syncytial Virus infection promotes necroptosis and HMGB1 release by airway epithelial cells
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- Journal Article
- A1
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Human lung conventional dendritic cells orchestrate lymphoid neogenesis during chronic obstructive pulmonary disease
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Meta-analyses of dupilumab versus standard of care in patients with uncontrolled, persistent asthma
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Dupilumab improves asthma control as assessed by total and individual item scores of the 6-item asthma control questionnaire in patients with severe chronic rhinosinusitis with nasal polyps and comorbid asthma : pooled results from the SINUS-24 and SINUS-52 phase 3 studies
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Dupilumab reduced severe exacerbations and improved lung function in patients with uncontrolled, moderate-to-severe asthma with an eosinophilic phenotype across baseline IgE levels : LIBERTY ASTHMA QUEST study
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Dupilumab improved asthma control and health-related quality of life in patients with oral-corticosteroid-dependent severe asthma in the phase 3 LIBERTY ASTHMA VENTURE study
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Modulation of innate lymphoid cell subsets in a mouse model of isocyanate-induced asthma
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Chronic use of oral corticosteroids in severe asthmatics in the Belgian Severe Asthma Registry (BSAR)
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Demographics and characteristics at diagnosis of patients with idiopathic pulmonary fibrosis (IPF) in a real-world setting : findings from 382 patients in the PROOF NEXT registry
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Azithromycin during acute chronic obstructive pulmonary disease exacerbations requiring hospitalization (BACE) : a multicenter, randomized, double-blind, placebo-controlled trial
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Efficacy of mepolizumab in patients with severe eosinophilic asthma by age of asthma onset : meta-analysis of two phase III trials
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Exacerbation rate reduction according to baseline blood eosinophilic count in patients with asthma treated with ICS/LABA maintenance and reliever therapy
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Effect of a 3-month low-dose azithromycin intervention for COPD exacerbations requiring hospitalization on subsequent respiratory events and mortality : the BACE trial
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Expression of receptor interacting protein kinase-3 and mixed lineage kinase domain-like protein in patients with COPD
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- Journal Article
- A1
- open access
Clinical significance of upper airway virus detection in critically ill hematology patients
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- Journal Article
- A1
- open access
Omega-3 fatty acids and genome-wide interaction analyses reveal DPP10-pulmonary function association
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The effect of fine particulate matter on the inflammatory responses in human upper airway mucosa
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Dupilumab improved morning and evening daily asthma symptoms in patients with oral-corticosteroid-dependent severe asthma in the phase 3 LIBERTY ASTHMA VENTURE study
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Dupilumab produces rapid and sustained improvements in asthma-related symptoms in patients with uncontrolled, moderate-to-severe asthma from the LIBERTY ASTHMA QUEST study
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Timing of dialysis in sepsis and acute respiratory distress syndrome
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Staphylococcus aureus induces a mucosal type 2 immune response via epithelial cell-derived cytokines
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Rhinovirus species-specific antibodies differentially reflect clinical outcomes in health and asthma
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The practice of respect in the ICU
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- Journal Article
- A1
- open access
The significance of eosinophilic inflammation in chronic obstructive pulmonary disease
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Dupilumab in patients with corticosteroid-dependent severe asthma : efficacy and safety results from the randomized, double-blind, placebo-controlled phase 3 LIBERTY ASTHMA VENTURE study
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A randomized, controlled phase 3 study, LIBERTY ASTHMA QUEST, evaluating the efficacy and safety of dupilumab in uncontrolled moderate-to-severe asthma
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The role of dicer in alveolar macrophages and dendritic cells in smoke-induced inflammation
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A multicenter randomized controlled trial of Zephyr endobronchial valve treatment in heterogeneous emphysema (TRANSFORM)
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MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease
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Peripheral artery disease in patients with chronic obstructive pulmonary disease
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Recovery after acute kidney injury
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Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in chronic obstructive pulmonary disease
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Direct detection of circulating microRNAs unveiled the absence of microRNA-218-5p in smoker subjects : reply
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Sputum neutrophil elastase as a biomarker for disease activity in bronchiectasis
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Impact of exacerbations on lung function in patients with asthma
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Treating acute kidney injury one less weapon in the armamentarium?
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The well-known gene HHIP and novel gene MECR are implicated in small airway obstruction
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Epidemiology of chronic bronchitis in chronic obstructive pulmonary disease (COPD)
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Meta-analysis of the association of serum vitamin D with pulmonary function
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Necroptosis: a novel cell death modality and its potential relevance for critical care medicine
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Chronic obstructive pulmonary disease and the risk of stroke: the Rotterdam study
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Lung function abnormalities in smokers with ischemic heart disease
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SplD- : a novel inhalant allergen from S. aureus causes Th2 bias in mice
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Microrna-218-5p is implicated in the pathogenesis of chronic obstructive pulmonary disease
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Women and lung disease : sex differences and global health disparities
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Physical inactivity as a missing link in understanding the progression of chronic obstructive pulmonary disease
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Natural T cell-mediated protection against seasonal and pandemic influenza : results of the Flu Watch cohort study
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Role of B cell-activating factor in chronic obstructive pulmonary disease
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Identification of differentially expressed microRNAs in neutrophilic asthma
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Determinants of procedural pain intensity in the intensive care unit : the Europain® study
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Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock
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Comparison of CT-based lobar ventilation models with helium-3 MRI ventilation measurements in asthmatics
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Functional respiratory imaging to evaluate PEEP induced bronchial and Alveolar recruitment in ARDS patients
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Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study
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Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease
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An inactivating caspase-11 passenger mutation muddles sepsis research
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Chronic obstructive pulmonary disease and cerebral microbleeds: the Rotterdam study
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The role of soluble guanylyl cyclase in Chronic Obstructive Pulmonary Disease
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Frailty affects quality of spirometry : the Rotterdam study
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Inhibition of necroptosis reduces cigarette smoke-induced epithelial cell-death and damage associated molecular pattern release in vitro and airway neutrophilia in mice
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Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension
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A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients
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Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
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C-Kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension
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Interleukin 6 (IL6) plasma levels, common variation In the IL6 gene and the risk of chronic obstructive pulmonary disease : a prospective population-based cohort study
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Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A
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Persistent activation of dendritic cells after resolution of allergic airway inflammation breaks tolerance to inhaled allergens in mice
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MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease
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Attributable mortality of ventilator associated pneumonia: a reappraisal using causal analysis
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Activation of the WNT/β-catenin pathway attenuates experimental emphysema
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Ventilator-associated pneumonia and cuff shape
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Diagnostic performance of soluble mesothelin and megakaryocyte potentiating factor in mesothelioma
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Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma
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New issues and controversies in the prevention of ventilator-associated pneumonia
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Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD
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Reduced expression of pentraxin-3 in the lungs of patients with COPD
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Prevalence and Factors of Intensive Care Unit Conflicts The Conflicus Study
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A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-alpha Blockade in Severe Persistent Asthma
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Dendritic cells in chronic obstructive pulmonary disease - New players in an old game