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- 2017
- Cobalt carbonyl-catalyzed carbonylation of functionalized aziridines to versatile β-lactam building blocks
- Use of α,ω-dichloroketimine building blocks for the construction of 1-azabicyclo[3.1.0]hexanes, piperidines, pyridines, pyrroles and tetrahydroindoles
- Carbonylation of aziridines as a powerful tool for the synthesis of functionalized β-lactams
- Reactivity of 3-oxo-β-lactams with respect to primary amines : an experimental and computational approach
- 2016
- Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl)azetidin-2-ones and their transformation into 3,4-oxolane-fused bicyclic β-lactams
- Synthesis of trifluoromethylated azetidines, aminopropanes, 1,3-oxazinanes, and 1,3-oxazinan-2-ones starting from 4-trifluoromethyl-β-lactam building blocks
- Deployment of small-ring azaheterocycles as building blocks for the synthesis of organofluorine compounds
- Synthesis and applications of 3-methylene-4-(trifluoromethyl)azetidin-2-ones as building blocks for the preparation of mono- and spirocyclic 4-CF3-β-lactams
- 2015
- Synthesis and antimicrobial/cytotoxic assessment of ferrocenyl oxazinanes, oxazinan-2-ones, and tetrahydropyrimidin-2-ones
- 2014
- Selective synthesis of cis- and trans-2-(methyl/phenyl)-3-(trifluoromethyl)aziridines and their regio- and stereospecific ring opening
- Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines
- Synthesis of novel thymine-β-lactam hybrids and evaluation of their anti-tumor activity
- 2013
- Nucleophile-directed selective transformation of cis-1-tosyl-2-toxyloxymethyl-3-(trifluoromethyl)aziridine into aziridines, azetidines, and benzo-fused dithianes, oxathianes, dioxanes, and (thio)morpholines
- Synthesis of 2-hydroxy-1,4-oxazin-3-ones through ring transformation of 3-hydroxy-4-(1,2-dihydroxyethyl)-β-lactams and a study of their reactivity
- 2012
- Chemical and enzymatic synthesis of 2-(2-carbamoylethyl)- and 2-(2-carboxyethyl)aziridines and their conversion into δ-lactams and γ-lactones
- Regioselectivity in the ring opening of non-activated aziridines
- N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis
- 2011
- Transformation of trans-4-aryl-3-chloro-1-(2-chloroethyl)azetidin-2-ones into 3-aryl-2-(ethylamino)propan-1-ols via intermediate 1-(1-aryl-2-chloro-3-hydroxypropyl)aziridines and trans-2-aryl-3-(hydroxymethyl)aziridines
- Synthesis and reactivity of spiro-fused β-lactams
- Straightforward synthesis of 1-alkyl-2-(trifluoromethyl)aziridines starting from 1,1,1-trifluoroacetone
- 2010
- Rhodium-catalysed hydroformylation of N-(2-propenyl)-β-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)but-1-enyl]acetamides
- Microwave-assisted regioselective ring opening of non-activated aziridines by lithium aluminium hydride
- Synthesis of 3,4-fused bicyclic β-lactams and their transformation into methyl cis-3-aminotetrahydrofuran-2-carboxylates
- Conjugate addition of 2-(bromomethyl)- and 2-(2-bromoethyl)piperidine to alkyl acrylates: application towards the synthesis of 2-(methoxycarbonyl)indolizidine
- Use of functionalized β-lactams as building blocks in heterocyclic chemistry
- 2009
- Synthesis of novel 2-alkoxy-3-amino-3-arylpropan-1-ols and 5-alkoxy-4-aryl-1,3-oxazinanes with antimalarial activity
- Diastereoselective Synthesis of Bicyclic gamma-Lactams via Ring Expansion of Monocydic beta-Lactams
- Synthesis of 2-[(arylmethylene)amino]cyclopropanecarbonitriles via a two-step ring transformation of 2-(cyanomethyl)aziridines