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2-((3,5-Dinitrobenzyl)thio)quinazolinones : potent antimycobacterial agents activated by deazaflavin (F420)-dependent nitroreductase (Ddn)
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Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors
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- Journal Article
- A1
- open access
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents
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- Journal Article
- A1
- open access
1-(1-Arylethylpiperidin-4-yl)thymine analogs as antimycobacterial TMPK inhibitors
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Structure guided lead generation toward nonchiral M. tuberculosis thymidylate kinase inhibitors
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- Journal Article
- A1
- open access
Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents
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Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase
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- Journal Article
- A1
- open access
Synthetic fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-D-xylulose 5-phosphate reductoisomerase or Plasmodium falciparum growth in vitro