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In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality
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- Journal Article
- A1
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T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources
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Fight fire with fire : gene therapy strategies to cure HIV
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In vitro generation of AML-specific T cells from human hematopoietic progenitor cells : a step towards curing acute myeloid leukemia?
(2014) -
- Journal Article
- A1
- open access
T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells
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Rho GTPase Cdc42 is essential for human T-cell development