Ghent University Academic Bibliography

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Structure-activity relationship exploration of 3’-deoxy-7-deazapurine nucleoside analogues as anti-Trypanosoma brucei agents

Fabian Hulpia (UGent) , Gustavo Daniel Campagnaro, Khalid J. Alzahrani, Ibrahim A. Alfayez, Marzuq A. Ungogo, Dorien Mabille, Louis Maes, Harry P. de Koning, Guy Caljon and Serge Van Calenbergh (UGent)

(2020) ACS INFECTIOUS DISEASES. 6(8). p.2045-2056
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The effect of selenium and zinc on CD4(+) count and opportunistic infections in HIV/AIDS patients : a randomized double blind trial

Azar Hadadi, Afshin Ostovar, Behnaz Edalat Noor, Mehrnaz Rasoolinejad, Mahboobeh Haji Abdolbaghi, Sahar Yousefi, Hossein Khalili, Gita Manshoori, Patricia Khashayar (UGent) , Zahra Alipour, et al.

(2020) ACTA CLINICA BELGICA. 75(3). p.170-176
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Predominance of the heterozygous CCR5 delta‐24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface

Vic Arendt, Mathieu Amand, Gilles Iserentant, Morgane Lemaire, Cécile Masquelier, Gilles F Ndayisaba, Chris Verhofstede (UGent) , Etienne Kariba, Susan Allen, Andy Chevigné, et al.

(2019) JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 22(9).
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Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

Marion Pardons (UGent) , AE Baxter, M Massanella, A Pagliuzza, R Fromentin, C Dufour, L Leyre, JP Routy, DE Kaufmann and N Chomont

(2019) PLOS PATHOGENS. 15(2).
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Latency-reversing agents induce differential responses in distinct memory CD4 T cell subsets in individuals on antiretroviral therapy

Marion Pardons (UGent) , R Fromentin, A Pagliuzza, JP Routy and N Chomont

(2019) CELL REPORTS. 29(9). p.2783-2795.e5
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Establishment of latent HIV-1 reservoirs : what do we really know?

Jef Vanhamel (UGent) , Anne Bruggemans and Zeger Debyser

(2019) JOURNAL OF VIRUS ERADICATION. 5(1). p.3-9
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Frequency of occurrence of HIV-1 dual infection in a Belgian MSM population

Laura Hebberecht, Leen Vancoillie (UGent) , Marlies Schauvliege (UGent) , Delfien Staelens (UGent) , Kenny Dauwe (UGent) , Virginie Mortier (UGent) and Chris Verhofstede (UGent)

(2018) PLOS ONE. 13(4).
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Which HIV-infected adults with high CD4 T-cell counts benefit most from immediate initiation of antiretroviral therapy? : a post-hoc subgroup analysis of the START trial

Jean-Michel Molina, Birgit Grund, Fred Gordin, Ian Williams, Mauro Schechter, Marcello Losso, Matthew Law, Ernest Ekong, Noluthando Mwelase, Athanasios Skoutelis, et al.

(2018) LANCET HIV. 5(4). p.e172-e180
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Fight fire with fire : gene therapy strategies to cure HIV

Jon Huyghe (UGent) , Magdalena Sips (UGent) and Linos Vandekerckhove (UGent)

(2017) EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. 15(8). p.747-758
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Deep sequencing of HIV-1 RNA and DNA in newly diagnosed patients with baseline drug resistance showed no indications for hidden resistance and is biased by strong interference of hypermutation

Kenny Dauwe (UGent) , Delfien Staelens (UGent) , Leen Vancoillie (UGent) , Virginie Mortier (UGent) and Chris Verhofstede (UGent)

(2016) JOURNAL OF CLINICAL MICROBIOLOGY. 54(6). p.1605-1615
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HIV triggers a cGAS-dependent, Vpu- and Vpr-regulated type I interferon response in CD4+ T cells

JOLIEN VERMEIRE (UGent) , Ferdinand Roesch, Daniel Sauter, Réjane Rua, Dominik Hotter, Anouk Van Nuffel (UGent) , Hanne Vanderstraeten (UGent) , Evelien Naessens (UGent) , Veronica Iannucci (UGent) , Alessia Landi (UGent) , et al.

(2016) CELL REPORTS. 17(2). p.413-424
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Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection

Kristin Höhne, Ramona Businger, Anouk Van Nuffel (UGent) , Sebastian Bolduan, Herwig Koppensteiner, Ann Baeyens (UGent) , JOLIEN VERMEIRE (UGent) , Eva Malatinková (UGent) , Bruno Verhasselt (UGent) and Michael Schindler

(2016) OPEN BIOLOGY. 6(7).
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Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay

Wim Trypsteen (UGent) , Pejman Mohammadi, Clarissa Van Hecke, Pieter Mestdagh (UGent) , Steve Lefever (UGent) , Yvan Saeys (UGent) , Pieter De Bleser (UGent) , Jo Vandesompele (UGent) , Angela Ciuffi, Linos Vandekerckhove (UGent) , et al.

(2016) SCIENTIFIC REPORTS. 6.
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SAMHD1's protein expression profile in humans

Sarah Schmidt, Kristina Schenkova, Tarek Adam, Elina Erikson, Judith Lehmann-Koch, Serkan Sertel, Bruno Verhasselt (UGent) , Oliver T Fackler, Felix Lasitschka and Oliver T Keppler

(2015) JOURNAL OF LEUKOCYTE BIOLOGY. 98(1). p.5-14
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Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and mucosal reservoirs

Eva Malatinková (UGent) , Ward De Spiegelaere (UGent) , Pawel Bonczkowski (UGent) , Maja Kiselinova (UGent) , Wim Trypsteen (UGent) , Margaret Johnson, Chris Verhofstede (UGent) , Danny De Looze (UGent) , Charles Murray, Sabine Kinloch-de Loes, et al.

(2015) ELIFE. 4.
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Keeping your armour intact : how HIV-1 evades detection by the innate immune system : HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS

Jonathan Maelfait (UGent) , Elena Seiradake and Jan Rehwinkel

(2014) BIOESSAYS. 36(7). p.649-657
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Lactobacillus-dominated cervicovaginal microbiota associated with reduced HIV/STI prevalence and genital HIV viral load in African women

Hanneke Borgdorff, Evgeni Tsivtsivadze, Rita Verhelst, Massimo Marzorati (UGent) , Suzanne Jurriaans, Gilles F Ndayisaba, Frank H Schuren and Janneke HHM van de Wijgert

(2014) ISME JOURNAL. 8(9). p.1781-1793
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Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation

Alessia Landi (UGent) , JOLIEN VERMEIRE (UGent) , Veronica Iannucci (UGent) , Hanne Vanderstraeten (UGent) , Evelien Naessens (UGent) , Mostafa Bentahir (UGent) and Bruno Verhasselt (UGent)

(2014) RETROVIROLOGY. 11.
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Antiretrovirals for HIV prevention: when should they be recommended?

Maja Kiselinova (UGent) , Ward De Spiegelaere (UGent) , Chris Verhofstede (UGent) , Steven Callens (UGent) and Linos Vandekerckhove (UGent)

(2014) EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. 12(4). p.431-445
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SAMHD1-dependent retroviral control and escape in mice

Jan Rehwinkel, Jonathan Maelfait (UGent) , Anne Bridgeman, Rachel Rigby, Bruce Hayward, Rachel A Liberatore, Paul D Bieniasz, Greg J Towers, Luis F Moita, Yanick J Crow, et al.

(2013) EMBO JOURNAL. 32(18). p.2454-2462
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HIV-1 tropism determination using a phenotypic Env recombinant viral assay highlights overestimation of CXCR4-usage by genotypic prediction algorithms for CRRF01_AE and CRF02_AG

Martin Mulinge, Morgane Lemaire, Jean-Yves Servais, Arkadiusz Rybicki, Daniel Struck, Eveline Santos da Silva, Chris Verhofstede (UGent) , Yolanda Lie, Carole Seguin-Devaux, Jean-Claude Schmit, et al.

(2013) PLOS ONE. 8(5).
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Limited cross-border infections in patients newly diagnosed with HIV in Europe

Dineke Frentz, Annemarie MJ Wensing, Jan Albert, Dimitrios Paraskevis, Ana B Abecasis, Osamah Hamouda, Louise B Jørgensen, Claudia Kücherer, Daniel Struck, Jean-Claude Schmit, et al.

(2013) RETROVIROLOGY. 10.
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Many stimuli pull the necrotic trigger, an overview

Nele Vanlangenakker (UGent) , Tom Vanden Berghe (UGent) and Peter Vandenabeele (UGent)

(2012) CELL DEATH AND DIFFERENTIATION. 19(1). p.75-86
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- Miscellaneous
HIV vaccines: can CD4⁺ T cells be of help?

Eva Van Braeckel (UGent) and Geert Leroux-Roels (UGent)

(2012) HUMAN VACCINES & IMMUNOTHERAPEUTICS. 8(12). p.1795-1798
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HIV type 1 mother-to-child transmission facilitated by distinctive glycosylation sites in the gp120 envelope glycoprotein

Elly Baan, Anthony de Ronde, Stanley Lüchters (UGent) , Joseph Vyankandondera, Joep M Lange, Georgios Pollakis and William A Paxton

(2012) AIDS RESEARCH AND HUMAN RETROVIRUSES. 28(7). p.715-724
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Ultra-deep sequencing of HIV-1 reverse transcriptase before start of an NNRTI-based regimen in treatment-naive patients

Peter Messiaen (UGent) , Chris Verhofstede (UGent) , Ina Vandenbroucke, Sylvie Dinakis (UGent) , Veerle Van Eygen, Kim Thys, Bart Winters, Jeroen Aerssens, Dirk Vogelaers (UGent) , Lieven J Stuyver, et al.

(2012) VIROLOGY. 426(1). p.7-11
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Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice

J Symons, Linos Vandekerckhove (UGent) , R Paredes, Chris Verhofstede (UGent) , R Bellido, Els Demecheleer (UGent) , PM van Ham, SFL van Lelyveld, AJ Stam, D van Versendaal, et al.

(2012) CLINICAL MICROBIOLOGY AND INFECTION. 18(6). p.606-612
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Cervical HIV-1 RNA shedding after cryotherapy among HIV-positive women with cervical intraepithelial neoplasia stage 2 or 3

Michael Chung (UGent) , Kevin P. McKenzie, Barbra A. Richardson, Grace C. John-Stewart, Robert W. Coombs, Hugo De Vuyst, Julia W. Njoroge, Evans Nyongesa-Malava, Samah R. Sakr and Nelly R. Mugo

(2011) AIDS. 25(15). p.1915-1919
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Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment

Linos Vandekerckhove (UGent) , Chris Verhofstede (UGent) , Els Demecheleer (UGent) , Stephane De Wit, Eric Florence, Katrien Fransen, Michel Moutschen, Wendy Mostmans, Kabamba Kabeya, Nicola Mackie, et al.

(2011) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 66(2). p.265-272
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European guidelines on the clinical management of HIV-1 tropism testing

Linos Vandekerckhove (UGent) , AMJ Wensing, R Kaiser, F Brun-Vézinet, B Clotet, A De Luca, S Dressler, F Garcia, AM Geretti, T Klimkait, et al.

(2011) LANCET INFECTIOUS DISEASES. 11(5). p.394-407
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Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis

Andreas Loos, Bart Van Droogenbroeck, Stefan Hillmer, Josephine Grass, Martin Pabst, Alexandra Castilho, Renate Kunert, Mifang Liang, Elsa Arcalis, David G Robinson, et al.

(2011) PLANT PHYSIOLOGY. 155(4). p.2036-2048
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Production of monoclonal antibodies with a controlled N-glycosylation pattern in seeds of Arabidopsis thaliana

Andreas Loos, Bart Van Droogenbroeck, Stefan Hillmer, Josephine Grass, Renate Kunert, Jingyuan Cao, David G Robinson, Anna Depicker (UGent) and Herta Steinkellner

(2011) PLANT BIOTECHNOLOGY JOURNAL. 9(2). p.179-192
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Intravaginal Practices, Vaginal Infections and HIV Acquisition: Systematic Review and Meta-Analysis

Adriane Hilber, Suzanna Francis, Matthew Chersich (UGent) , Pippa Scott, Shelagh Redmond, Nicole Bender, Paolo Miotti, Marleen Temmerman (UGent) and Nicola Low

(2010) PLOS ONE. 5(2).
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Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections

Kristen Chalmet (UGent) , Delfien Staelens (UGent) , Stijn Blot (UGent) , Sylvie Dinakis (UGent) , Jolanda Pelgrom (UGent) , Jean Plum (UGent) , Dirk Vogelaers (UGent) , Linos Vandekerckhove (UGent) and Chris Verhofstede (UGent)

(2010) BMC INFECTIOUS DISEASES. 10.
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High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates

Jens Verheyen, Chris Verhofstede (UGent) , Elena Knops, Linos Vandekerckhove (UGent) , Axel Fun, Diede Brunen, Kenny Dauwe (UGent) , Annemarie MJ Wensing, Herbert Pfister, Rolf Kaiser, et al.

(2010) AIDS. 24(5). p.669-673
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Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients

Linos Vandekerckhove (UGent) , Chris Verhofstede (UGent) and Dirk Vogelaers (UGent)

(2009) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 63(6). p.1087-1096
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Hyperactivated NF-κB and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells

Matladi N Ndlovu, Carine Van Lint, Karlien Van Wesemael (UGent) , Pieter Callebert (UGent) , Dany Chalbos, Guy Haegeman (UGent) and Wim Vanden Berghe (UGent)

(2009) MOLECULAR AND CELLULAR BIOLOGY. 29(20). p.5488-5504
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Identification and genotyping of bacteria from paired vaginal and rectal samples from pregnant women indicates similarity between vaginal and rectal microflora

Nabil El Aila (UGent) , Inge Tency (UGent) , Geert Claeys (UGent) , Hans Verstraelen (UGent) , Bart Saerens (UGent) , Guido Lopes dos Santos Santiago (UGent) , Ellen De Backer (UGent) , Piet Cools (UGent) , Marleen Temmerman (UGent) , Rita Verhelst, et al.

(2009) BMC INFECTIOUS DISEASES. 9.
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Pediatric HIV infection : the state of antiretroviral therapy

Mehri S McKellar, Steven Callens (UGent) and Robert Colebunders

(2008) EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. 6(2). p.167-180
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HIV care and treatment for children in resource-limited settings

Steven Callens (UGent) , Mehri S McKellar and Robert Colebunders

(2008) EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. 6(2). p.181-190
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The Tandem PDZ Protein Syntenin Interacts with the Aminoacyl tRNA Synthetase Complex in a Lysyl-tRNA Synthetase-Dependent Manner

Kris Meerschaert, Eline Remue (UGent) , Ariane De Ganck (UGent) , An Staes (UGent) , Ciska Boucherie (UGent) , Kris Gevaert (UGent) , Joël Vandekerckhove (UGent) , Lawrence Kleiman and Jan Gettemans (UGent)

(2008) JOURNAL OF PROTEOME RESEARCH. 7(11). p.4962-4973
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Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml

Chris Verhofstede (UGent) , Filip Van Wanzeele (UGent) , Beatrijs Van Der Gucht (UGent) , Jolanda Pelgrom (UGent) , Linos Vandekerckhove (UGent) , Jean Plum (UGent) and Dirk Vogelaers (UGent)

(2007) JOURNAL OF MEDICAL VIROLOGY. 79(9). p.1254-1260
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Cellular co-factors of HIV-1 integration

Bénédicte Van Maele, Katrien Busschots, Linos Vandekerckhove (UGent) , Frauke Christ and Zeger Debyser

(2006) TRENDS IN BIOCHEMICAL SCIENCES. 31(2). p.98-105
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Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy

Hans Verstraelen (UGent) , Joris Delanghe (UGent) , Kristien Roelens (UGent) , Stijn Blot (UGent) , Geert Claeys (UGent) and Marleen Temmerman (UGent)

(2005) BMC INFECTIOUS DISEASES. 5.
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Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

Stéphane Emiliani, Aurélie Mousnier, Katrien Busschots, Marlène Maroun, Bénédicte Van Maele, Denis Tempe, Linos Vandekerckhove (UGent) , Fanny Moisant, Lilia Ben-Slama, Myriam Witvrouw, et al.

(2005) JOURNAL OF BIOLOGICAL CHEMISTRY. 280(27). p.25517-25523
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Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

M Samson, F Libert, BJ Doranz, J Rucker, C Liesnard, C-M Farber, S Saragosti, C Lapouméroulie, J Cogniaux, C Forceille, et al.

(1996) NATURE. 382(6593). p.722-725
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Concurrence of high levels of interferons α and β in cord and maternal blood and simultaneous presence of interferon in trophoblast in an African population

Peter Ebbesen, Henrik Hager, Niels Nørskov-Lauritsen, George Aboagye-Mathiesen, Milan Zdravkovic, Jan Villadsen, Xiangdong Liu, Peter M Petersen, Charanjit Bambra, Aggrey Nyongo, et al.

(1995) JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. 15(2). p.123-128
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The complete consensus V3 loop peptide of the envelope protein gp120 of HIV-1 shows pronounced helical character in solution

Wim Vranken, M Budesinsky, Franky Fant, Kris Boulez and Frans Borremans (UGent)

(1995) FEBS LETTERS. 374(1). p.117-121

Structure-activity relationship exploration of 3’-deoxy-7-deazapurine nucleoside analogues as anti-Trypanosoma brucei agents

The effect of selenium and zinc on CD4(+) count and opportunistic infections in HIV/AIDS patients : a randomized double blind trial

Predominance of the heterozygous CCR5 delta‐24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

Latency-reversing agents induce differential responses in distinct memory CD4 T cell subsets in individuals on antiretroviral therapy

Establishment of latent HIV-1 reservoirs : what do we really know?

Frequency of occurrence of HIV-1 dual infection in a Belgian MSM population

Which HIV-infected adults with high CD4 T-cell counts benefit most from immediate initiation of antiretroviral therapy? : a post-hoc subgroup analysis of the START trial

Fight fire with fire : gene therapy strategies to cure HIV

Deep sequencing of HIV-1 RNA and DNA in newly diagnosed patients with baseline drug resistance showed no indications for hidden resistance and is biased by strong interference of hypermutation

HIV triggers a cGAS-dependent, Vpu- and Vpr-regulated type I interferon response in CD4+ T cells

Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection

Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay

SAMHD1's protein expression profile in humans

Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and mucosal reservoirs

Keeping your armour intact : how HIV-1 evades detection by the innate immune system : HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS

Lactobacillus-dominated cervicovaginal microbiota associated with reduced HIV/STI prevalence and genital HIV viral load in African women

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation

Antiretrovirals for HIV prevention: when should they be recommended?

SAMHD1-dependent retroviral control and escape in mice

HIV-1 tropism determination using a phenotypic Env recombinant viral assay highlights overestimation of CXCR4-usage by genotypic prediction algorithms for CRRF01_AE and CRF02_AG

Limited cross-border infections in patients newly diagnosed with HIV in Europe

Many stimuli pull the necrotic trigger, an overview

HIV vaccines: can CD4⁺ T cells be of help?

HIV type 1 mother-to-child transmission facilitated by distinctive glycosylation sites in the gp120 envelope glycoprotein

Ultra-deep sequencing of HIV-1 reverse transcriptase before start of an NNRTI-based regimen in treatment-naive patients

Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice

Cervical HIV-1 RNA shedding after cryotherapy among HIV-positive women with cervical intraepithelial neoplasia stage 2 or 3

Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment

European guidelines on the clinical management of HIV-1 tropism testing

Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis

Production of monoclonal antibodies with a controlled N-glycosylation pattern in seeds of Arabidopsis thaliana

Intravaginal Practices, Vaginal Infections and HIV Acquisition: Systematic Review and Meta-Analysis

Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections

High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates

Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients

Hyperactivated NF-κB and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells

Identification and genotyping of bacteria from paired vaginal and rectal samples from pregnant women indicates similarity between vaginal and rectal microflora

Pediatric HIV infection : the state of antiretroviral therapy

HIV care and treatment for children in resource-limited settings

The Tandem PDZ Protein Syntenin Interacts with the Aminoacyl tRNA Synthetase Complex in a Lysyl-tRNA Synthetase-Dependent Manner

Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml

Cellular co-factors of HIV-1 integration

Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Concurrence of high levels of interferons α and β in cord and maternal blood and simultaneous presence of interferon in trophoblast in an African population

The complete consensus V3 loop peptide of the envelope protein gp120 of HIV-1 shows pronounced helical character in solution