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- Journal Article
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- open access
Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos
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Molecular therapies and vaccines face the challenges of emerging infectious diseases
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- Journal Article
- A1
- open access
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity
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- Miscellaneous
- open access
Low-dose single-shot COVID-19 mRNA vaccines lie ahead
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In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation
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Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs
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Corticosteroids and mRNA vaccines : a word of caution
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Early signs of clinical activity in Aml patients receiving NKG2D CAR T cell therapy in the absence of pre-conditioning chemotherapy : an alternative strategy to CAR T cell therapy
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- Journal Article
- A1
- open access
Modulation of protein-protein interactions for the development of novel therapeutics
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Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8
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Coadministration of a plasmid encoding HIV-1 Gag enhances the efficacy of cancer DNA vaccines
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Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses
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- Journal Article
- A1
- open access
Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional cis-regulatory motifs that enable efficient cardiac gene therapy
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- Journal Article
- A1
- open access
Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates
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Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model
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Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
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Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses
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- Journal Article
- A1
- open access
The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls
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Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved
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Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemia
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Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells
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The internalization route resulting in successful gene expression depends on polyethylenimine both cell line and polyplex type
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Angiogenesis enhances factor IX delivery and persistence from retrievable human bioengineered muscle implants
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In vivo depletion of CD4⁺CD25⁺ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells
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Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: implications for cancer immunotherapy protocols