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Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.
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The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.
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Inhibition of Tumor Necrosis Factor-induced necrotic cell death by the zinc finger protein A20.
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- Journal Article
- A1
- open access
The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.
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Tumour necrosis factor: intracellular mechanism of action