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The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation
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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage
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Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials
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In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality
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T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources
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Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly
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Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage
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The checkpoint for agonist selection precedes conventional selection in human thymus
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Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities
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Chimeric antigen receptor transgenic, T cell receptor/CD3 negative monospecific T cells generated from cord blood CD34 positive cells