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RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
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- Journal Article
- A1
- open access
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
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SOX11 as guardian of epigenetic plasticity in neuroblastoma
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SOX11 as guardian of epigenetic plasticity in neuroblastoma
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma
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SOX11 as mediator of the adrenergic cell state in NB
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma
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The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype
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- Journal Article
- A1
- open access
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
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RRM2 is an essential and druggable component of the FOXM1 driven replicative stress DNA damage response in neuroblastoma