Ghent University Academic Bibliography

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Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children

Giorgia Bucciol, Isabelle Meyts, Laurent Abel, Salah Al-Muhsen, Alessandro Aiuti, Fahd Al-Mulla, Evangelos Andreakos, Novelli Antonio, Andrés A. Arias, Sophie Trouillet-Assant, et al.

(2023) JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 151(4). p.832-840
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Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

Danyel Lee, Jérémie Le Pen, Ahmad Yatim, Beihua Dong, Yann Aquino, Masato Ogishi, Rémi Pescarmona, Estelle Talouarn, Darawan Rinchai, Peng Zhang, et al.

(2023) SCIENCE. 379(6632).
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Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, et al.

(2023) GENOME MEDICINE. 15(1).
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TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi Hoste (UGent) , Lisa Roels (UGent) , Leslie Naesens (UGent) , Victor Bosteels (UGent) , Stijn Vanhee (UGent) , Sam Dupont (UGent) , Cedric Bosteels (UGent) , Robin Browaeys (UGent) , Niels Vandamme (UGent) , Kevin Verstaen (UGent) , et al.

(2022) JOURNAL OF EXPERIMENTAL MEDICINE. 219(2).
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Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

Qian Zhang, Daniela Matuozzo, Jérémie Le Pen, Danyel Lee, Leen Moens, Takaki Asano, Jonathan Bohlen, Zhiyong Liu, Marcela Moncada-Velez, Yasemin Kendir-Demirkol, et al.

(2022) JOURNAL OF EXPERIMENTAL MEDICINE. 219(8).
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A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

Evangelos Andreakos, Laurent Abel, Donald C. Vinh, Elżbieta Kaja, Beth A. Drolet, Qian Zhang, Cliona O’Farrelly, Giuseppe Novelli, Carlos Rodríguez-Gallego, Filomeen Haerynck (UGent) , et al.

(2022) NATURE IMMUNOLOGY. 23(2). p.159-164
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Human genetic and immunological determinants of critical COVID-19 pneumonia

Qian Zhang, Paul Bastard, Adem Karbuz, Adrian Gervais, Ahmad Abou Tayoun, Alessandro Aiuti, Alexandre Belot, Alexandre Bolze, Alexandre Gaudet, Anastasiia Bondarenko, et al.

(2022) NATURE. 603(7902). p.587-598
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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry, Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, Marina Garcia-Prat, et al.

(2022) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 119(21).
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X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi, Daniela Matuozzo, Marcela Moncada-Velez, Majistor Raj Luxman Maglorius Renkilaraj, Peng Zhang, Laurent Meertens, Alexandre Bolze, Marie Materna, et al.

(2021) SCIENCE IMMUNOLOGY. 6(62).
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SARS-CoV-2–related MIS-C : a key to the viral and genetic causes of Kawasaki disease?

Vanessa Sancho-Shimizu, Petter Brodin, Aurélie Cobat, Catherine M. Biggs, Julie Toubiana, Carrie L. Lucas, Sarah E. Henrickson, Alexandre Belot, Elie Haddad, Kathie Beland, et al.

(2021) JOURNAL OF EXPERIMENTAL MEDICINE. 218(6).
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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Jérémy Manry, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, Marina Garcia-Prat, et al.

(2021) SCIENCE IMMUNOLOGY. 6(62).
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Yu Zhang, Karim Dorgham, Quentin Philippot, Jeremie Rosain, Vivien Beziat, et al.

(2020) SCIENCE. 370(6515).
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu, Jérémie Le Pen, Marcela Moncada-Velez, Jie Chen, Masato Ogishi, Ira K. D. Sabli, Stephanie Hodeib, Cecilia Korol, et al.

(2020) SCIENCE. 370(6515). p.422-+
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Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections

Benson Ogunjimi (UGent) , Shen-Ying Zhang, Katrine B Sørensen, Kristian A Skipper, Madalina Carter-Timofte, Gaspard Kerner, Stefanie Luecke, Thaneas Prabakaran, Yujia Cai, Josephina Meester, et al.

(2017) JOURNAL OF CLINICAL INVESTIGATION. 127(9). p.3543-3556

Academic Bibliography

Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children

Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

Human genetic and immunological determinants of critical COVID-19 pneumonia

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

SARS-CoV-2–related MIS-C : a key to the viral and genetic causes of Kawasaki disease?

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections

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