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Systematic comparison of experimental and human obstructive cholestasis reveals conservation of canonical pathway activation and biomarkers relevant for cholestatic liver disease
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- Journal Article
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Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis
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Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma
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- Journal Article
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In vivo and in vitro models of hepatocellular carcinoma : current strategies for translational modeling
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Dataset on transcriptomic profiling of cholestatic liver injury induced by food additives and a cosmetic ingredient
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- Journal Article
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Rodent models of cholestatic liver disease : a practical guide for translational research
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- Journal Article
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Astrocytic Connexin43 channels as candidate targets in epilepsy treatment
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- Journal Article
- A2
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Dataset on transcriptomic profiling of cholestatic liver injury in an in vitro and in vivo animal model
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Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury
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Mechanisms and in vitro models of drug-induced cholestasis
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Connexin and pannexin (hemi)channels : emerging targets in the treatment of liver disease
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- Journal Article
- A1
- open access
TAT-Gap19 and carbenoxolone alleviate liver fibrosis in mice
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- Journal Article
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Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents
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Connexin hemichannel inhibition reduces acetaminophen-induced liver injury in mice
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- Journal Article
- A1
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Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice
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Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?
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Pannexin1 as mediator of inflammation and cell death
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- Journal Article
- A1
- open access
Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory
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- Journal Article
- A1
- open access
Connexins and their channels in inflammation
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Experimental models of liver fibrosis
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Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research
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- Journal Article
- A1
- open access
Development and characterization of a new human hepatic cell line
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Structure, regulation and function of gap junctions in liver
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- Journal Article
- A1
- open access
Connexin and pannexin (hemi)channels in the liver
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The dual face of connexin-based astroglial Ca2+ communication: a key player in brain physiology and a prime target in pathology
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- Journal Article
- A1
- open access
Strategies for immortalization of primary hepatocytes
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Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury
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IP₃, a small molecule with a powerful message
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Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures
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Proteomic analysis of global protein expression changes in the endothelin-1 rat model for cerebral ischemia : rescue effect of mild hypothermia
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- Journal Article
- A1
- open access
Regulation of connexin- and pannexin-based channels by post-translational modifications
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Paracrine signaling through plasma membrane hemichannels
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Connexin43 signaling contributes to spontaneous apoptosis in cultures of primary hepatocytes
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Transfer of IP3 through gap junctions is critical, but not sufficient, for the spread of apoptosis
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Non-channel functions of connexins in cell growth and cell death
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Modulation of connexin signaling by bacterial pathogens and their toxins
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Characterization of spontaneous cell death in monolayer cultures of primary hepatocytes
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Connexins: sensors and regulators of cell cycling
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Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum
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Calcium and connexin-based intercellular communication, a deadly catch?
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Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood brain barrier permeability
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Critical selection of reliable reference genes for gene expression study in the HepaRG cell line
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DNA methyltransferase 3a expression decreases during apoptosis in primary cultures of hepatocytes
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Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death
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Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model.
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Connexin-related signaling in cell death: to live or let die?
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Epigenetic regulation of gap junctional intercellular communication: more than a way to keep cells quiet?
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Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells
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Biochemical characterisation of an in vitro model of hepatocellular apoptotic cell death.
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Calcium regulation of connexin-43 hemichannel-mediated ATP release in glial cells
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Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity
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Cell death communication via connexin channels investigated in a C6 glioma cell model