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- Journal Article
- A1
- open access
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
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Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
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Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC
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Genome-wide copy number variation scan identifies complement component C4 as novel susceptibility gene for Crohn's disease
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High-density mapping of the MHC identifies a shared role for HLA-DRB1⋆01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
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Risk of malignancies in patients with inflammatory bowel disease treated with thiopurines or anti-TNF alpha antibodies
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Predominant gut microbiota predict pouchitis following colectomy and IPAA in ulcerative colitis
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Practical aspects of genome-wide association interaction analysis
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Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis
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Discovering main genetic interactions with LABNet LAsso-Based Network Inference
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Active PAI-1 as marker for venous thromboembolism : case-control study using a comprehensive panel of PAI-1 and TAFI assays
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Behind the (impedance) baseline in children
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Genome-wide association interaction analysis for Alzheimer's disease
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Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
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Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood
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A comparison of multivariate genome-wide association methods
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- Conference Paper
- C3
- open access
The Belgian Registry of Pediatric Crohn's disease (BELCRO) : growth status after 3 year follow up
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Disease severity after 3 years of treating newly diagnosed pediatric Crohn's disease patients (The Belcro cohort)
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- Journal Article
- A1
- open access
An efficient algorithm to perform multiple testing in epistasis screening
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- Journal Article
- A1
- open access
A robustness study of parametric and non-parametric tests in model-based multifactor dimensionality reduction for epistasis detection
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Profile of pediatric Crohn's disease in Belgium
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Genetic variations in toll-like receptor pathway and lung function decline in Cystic Fibrosis patients
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Familial aggregation in the response to anti-TNF in inflammatory bowel disease patients
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Esophageal impedance baseline is age dependent
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Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress
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Molecular reclassification of Crohn's disease : a cautionary note on population stratification
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Unique gene expression and MR T-2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease
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Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease
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Neutrophil gelatinase B-associated lipocalin-matrix metalloproteinase-9 (NGAL-MMP-9) complex as a surrogate serum marker for mucosal healing in ulcerative colitis
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Haplotype information combined with iterative pruning PCA (ipPCA) to improve population clustering
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A novel integrated framework for rare variant analysis
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Integration analysis of 'OMICS' data using penalized regression methods : an application to bladder cancer
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EU Pancreas : an integrated European platform for pancreas cancer research : from basic science to clinical and public health interventions for a rare disease
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Therapeutic strategy and patient outcome during the first 2 years of pediatric Crohn’s disease
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Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colonization in cystic fibrosis patients
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Safety and cost of infliximab for the treatment of Belgian pediatric patients with Crohn’s disease
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Factors determining therapeutic strategy at diagnosis and evolution of disease severity in a cohort of Belgian pediatric Crohn's disease patients (BELCRO)
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Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma
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Travelling the world of gene-gene interactions
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Genetic variations in toll-like receptor pathway and lung function decline in cystic fibrosis patients
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Prognostic value of serologic and histologic markers on clinical relapse in ulcerative colitis patients with mucosal healing
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Repeated cycles of DSS inducing a chronically relapsing inflammation : a novel model to study fibrosis using in vivo MRI T2 relaxometry
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Clustering of Crohn's disease patients : identification of sub-phenotypes and population stratification
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- Journal Article
- A1
- open access
Does pet ownership in infancy lead to asthma or allergy at school age? : pooled analysis of individual participant data from 11 European birth cohorts
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Effects of haptoglobin polymorphisms and deficiency on susceptibility to inflammatory bowel disease and on severity of murine colitis
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An Ensemble pipeline to enable detection of epistasis in genomic data
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A robustness study to investigate the performance of parametric and non-parametric tests used in model-based multifactor dimensionality reduction epistasis detection
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Lower-order effects adjustment in quantitative traits model-based multifactor dimensionality reduction
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Heterogeneous nuclear RNPs as targets of autoantibodies in systemic rheumatic diseases
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Integration of biological data in the context of GWAI studies
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Sequential T2 relaxometry as a non-invasive assessment of transmural inflammation in a murine model of chronically relapsing colitis
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Effects of domperidone on QTc interval in infants
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Genome-wide epistasis screening for Crohn's disease
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Comparison of different methods for detecting gene-gene interactions in case-control data
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Challenges and opportunities in genome-wide environmental interaction (GWEI) studies
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Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis
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Levels of C-reactive protein are associated with response to infliximab therapy in patients with Crohn's disease
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Outcome of pregnancy in women with inflammatory bowel disease treated with antitumor necrosis factor therapy
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Perspectives on genome-wide multi-stage family-based association studies
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Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a Northern Swedish population
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A report of the First Biennial Meeting on Capita Selecta in Complex Disease Analysis (CSCDA2010), Leuven, Belgium, August 25-27, 2010
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Investigating Hardy-Weinberg equilibrium in case-control or cohort studies or meta-analysis
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Model-based multifactor dimensionality reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data
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Identification of a novel autoantigen in inflammatory bowel disease by protein microarray
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Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease
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The protease genes Cyld and USP40 are associated with Crohn's disease : results from a European consortium
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Rate of malignancies and infections in a large single center cohort of IBD patients treated with thiopurines and anti-TNF-antibodies
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Mucosal gene expression profiling differentiates early from late ileal Crohn's disease
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Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment
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Tolerability of shortened infliximab infusion times in patients with inflammatory bowel diseases : a single-center cohort study
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Model-based multifactor dimensionality reduction for detecting epistasis in case-control data in the presence of noise
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High-throughput method for comparative analysis of denaturing gradient gel electrophoresis profiles from human fecal samples reveals significant increases in two bifidobacterial species after inulin-type prebiotic intake
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mbmdr : an R package for exploring gene-gene interactions associated with binary or quantitative traits
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- Journal Article
- A1
- open access
FAM-MDR : a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals
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Familial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease
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Alternative risk cell definitions based on ranking improve performance of model-based multifactor dimensionality reduction for epistasis detection
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A two-stage approach to test for gene-gene interactions in family data based on within-family and between-family information
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Model-based multifactor dimensionality reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data
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A detailed view on model-based multifactor dimensionality reduction for detecting gene-gene interactions in case-control data in the absence and presence of noise
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Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease
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Molecular reclassification of Crohn's disease by cluster analysis of genetic variants
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Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk
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In utero smoke exposure and impaired response to inhaled corticosteroids in children with asthma
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Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk
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A screening methodology based on Random Forests to improve the detection of gene-gene interactions
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Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma
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A family-based association test to detect gene-gene interactions in the presence of linkage
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Small effect of the androgen receptor gene GGN repeat polymorphism on serum testosterone levels in healthy men
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Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men
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Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis
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Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment
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Genetic risk profiling and prediction of disease course in Crohn's disease patients
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Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease
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Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
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TECK and MADCAM-1 mucosal expression in active IBD : the effect of infliximab therapy
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The impact of infliximab therapy on colonic mucosal expression of barrier genes in patients with inflammatory bowel disease
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Predictive value of C-reactive protein level changes on the long term outcome of infliximab in Crohn's disease
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GENESTAT : an information portal for design and analysis of genetic association studies
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Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease : results from a single-centre cohort
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Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit
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Long-term outcome after infliximab for refractory ulcerative colitis
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TNFA-3086 > A in two international population-based cohorts and risk of asthma
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Microarray study of mucosal antimicrobial peptides in patients with inflammatory bowel disease before and after first infliximab treatment
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Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease
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Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients
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A family-based association test for quantitative traits to detect gene-gene interactions
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Heritability of blood concentrations of sex-steroids in relation to body composition in young adult male siblings
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Stability of gut microbiota over time in Crohn’s disease patients compared to healthy relatives
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Approaches to handling incomplete data in family-based association testing
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New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
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Pet ownership in eight European birth cohorts : results of a GA(2)LEN initiative
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Gene expression profiling to predict the response of infliximab in patients with UC
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Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients
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Mixed IBD families : a distinct entity within IBD
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Faecal bacterial DGGE profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls
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Eotaxin polymorphisms and serum total IgE levels in children with asthma
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T-bet polymorphisms are associated with asthma and airway hyperresponsiveness
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Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?
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Toll-like receptor-1,-2, and-6 polymorphisms influence disease extension in inflammatory bowel diseases
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Permutation based methods for comparing quality of life between observed treatments
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Comparison of linkage and association strategies for quantitative traits using the COGA dataset
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Genomic screening in family-based association testing
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Genomic screening in family based association testing and the multiple testing problem
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Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
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Paternal history of asthma and airway responsiveness in children with asthma
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Genomic screening and replication using the same data set in family-based association testing
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An equivalence test for comparing DNA sequences
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Crohn's disease and month of birth
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The value of patient-reported symptoms as prognostic factors for survival in advanced colorectal cancer
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Predicting survival using health related quality of life scores in glioblastoma cancers : findings from an international phase III randomised controlled trial
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Genome wide scan in a Flemish inflammatory bowel disease population : support for the IBD4 locus, population heterogeneity, and epistasis
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Pancreatic autoantibodies in inflammatory bowel disease
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Health-related quality of life parameters as prognostic factors in a nonmetastatic breast cancer population : an international multicenter study
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Interassay and interobserver variability in the detection of anti-neutrophil cytoplasmic antibodies in patients with ulcerative colitis
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Predicting survival with health-related quality of life scores in locally advanced breast cancer : results from an international randomized controlled trial
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Deficient host-bacteria interactions in inflammatory bowel disease? : the toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
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Introducing the multivariate dale model in population-based genetic association studies
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Transmission of CARD15 (NOD2) variants within families of patients with inflammatory bowel disease
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The value of serologic markers in indeterminate colitis : a prospective follow-up study : reply
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Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease : a prospective cohort study
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Guidelines for the use of epoetin : have quality-of-life benefits been proven?
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Transmission of CARD15 (NOD2) variants in families with Crohns disease
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Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30 : identification and impact on model selection
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Erythropoietin improves quality of life : a response
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Human recombinant erythropoietin and quality of life : a wonder drug or something to wonder about?
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Sensitivity analysis of longitudinal binary quality of life data with drop-out : an example using the EORTC QLQ-C30
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Introduction of the multivariate Dale model in genetic association studies
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An equivalence test for comparing DNA sequences
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Characterizations by automorphism groups of some rank 3 buildings, II : a half strongly-transitive locally finite triangle building is a Bruhat-Tits building
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Characterizations by automorphism groups of some rank 3 buildings, IV : hyperbolic p-adic Moufang buildings of rank 3
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Characterizations by automorphism groups of some rank 3 buildings, III : Moufang-like conditions
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Characterizations by automorphism groups of some rank 3 buildings, I : some properties of half strongly-transitive triangle buildings
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Moufang affine buildings have Moufang spherical buildings at infinity
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Non-spherical tits-buildings of rank 3
(1996)