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A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state
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- Journal Article
- A1
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Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication
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Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE
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Selected IL-1 activity on CD8+ T cells allows for safe enhancement of cellular immune responses
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- Journal Article
- A1
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Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant
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- Journal Article
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- open access
Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies
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Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice
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Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments
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A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment
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High efficiency targeting of IFN-α activity: possible applications in fighting tumours and infections