Ghent University Academic Bibliography

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A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases

Yanina Jansen, Vibeke Kruse (UGent) , Jurgen Corthals, Kelly Schats, Pieter-Jan van Dam, Teofila Seremet, Carlo Heirman, Lieve Brochez (UGent) , Mark Kockx, Kris Thielemans, et al.

(2020) CANCER IMMUNOLOGY IMMUNOTHERAPY. 69(12). p.2589-2598
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- Journal Article
- A1
- open access
Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Patrick Tjok Joe, Ioanna Christopoulou (UGent) , Lien Van Hoecke (UGent) , Bert Schepens (UGent) , Tine Ysenbaert (UGent) , Carlo Heirman, Kris Thielemans, Xavier Saelens (UGent) and Joeri Aerts

(2019) JOURNAL OF TRANSLATIONAL MEDICINE. 17.
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Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Willem Staels (UGent) , Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco de Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, et al.

(2018) DIABETOLOGIA. 61(8). p.1804-1810
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Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Kevin Van der Jeught, Stefaan De Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, Federico Perche, Sarah Maenhout, Sanne Bevers, Katrijn Broos, Kim Deswarte (UGent) , et al.

(2018) ACS NANO. 12(10). p.9815-9829
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Immune cell profiling of melanoma metastases from patients treated with TriMixDC-MEL dendritic cell therapy in combination with ipilimumab

Kelly Schats, Emily A Van Vre, Isolde Debyser, Arno Vandenbroeck, Yanina Jansen, Teofila Seremet, Koen Marien, Erik Fransen, Dorien Schrijvers, Wim Van Criekinge (UGent) , et al.

(2017) JOURNAL OF CLINICAL ONCOLOGY. 35(suppl. 15).
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- Journal Article
- A1
- open access
Current status and perspectives of immune-based therapies for hepatocellular carcinoma

Maridi Aerts, Daphné Benteyn, Hans Van Vlierberghe (UGent) , Kris Thielemans and Hendrik Reynaert

(2016) WORLD JOURNAL OF GASTROENTEROLOGY. 22(1). p.253-261
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- Journal Article
- A2
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Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

Katrijn Broos, Kevin Vanderjeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Kris Thielemans and Karine Breckpot

(2016) MOLECULAR THERAPY-NUCLEIC ACIDS. 5.
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The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Yannick Willemen, Johan M. J. Van den Bergh, Sarah Bonte (UGent) , Sebastien Anguille, Carlo Heirman, Barbara MH Stein, Herman Goossens, Tessa Kerre (UGent) , Kris Thielemans, Marc Peeters, et al.

(2016) ONCOTARGET. 7(45). p.73960-73970
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Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Lode Goethals, Sarah Maenhout, Daphné Benteyn, Cleo Goyvaerts, Stephanie Dufour, Kevin Van Der Jeught, Lukasz Bialkowski, et al.

(2016) CANCER IMMUNOLOGY RESEARCH. 4(2). p.146-156
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Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

Teofila Seremet, Alexander Koch (UGent) , Yanina Jansen, Max Schreuer, Sofie Wilgenhof, Véronique Del Marmol, Danielle Liènard, Kris Thielemans, Kelly Schats, Mark Kockx, et al.

(2016) JOURNAL OF TRANSLATIONAL MEDICINE. 14.

Academic Bibliography

A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Immune cell profiling of melanoma metastases from patients treated with TriMixDC-MEL dendritic cell therapy in combination with ipilimumab

Current status and perspectives of immune-based therapies for hepatocellular carcinoma

Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

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