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Dopamine D2 receptor occupancy as a predictor of catalepsy in rats: a pharmacokinetic-pharmacodynamic modeling approach
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Modelling and simulation of placebo effect: application to drug development in schizophrenia
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Sensitivity of individual items of the Positive and Negative Syndrome Scale (PANSS) and items subgroups to differentiate between placebo and drug treatment in schizophrenia
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Pharmacokinetic-pharmacodynamic modeling of antipsychotic drugs in patients with schizophrenia, part I: the use of PANSS total score and clinical utility
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Pharmacokinetic-pharmacodynamic modelling of antipsychotic drugs in patients with schizophrenia, part II: the use of subscales of the PANSS score
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Population pharmacokinetic-pharmacodynamic modeling of haloperidol in patients with schizophrenia using positive and negative syndrome rating scale
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- Journal Article
- A1
- open access
Pharmacokinetic-pharmacodynamic modeling of the D-2 and 5-HT2A receptor occupancy of risperidone and paliperidone in rats
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Structural models describing placebo treatment effects in schizophrenia and other neuropsychiatric disorders
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- Journal Article
- A1
- open access
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the dopamine D-2 receptor occupancy of olanzapine in rats