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Paradoxical onset of arrhythmic waves from depolarized areas in cardiac tissue due to curvature-dependent instability
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Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system
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Response by Feola et al. to letter regarding article, 'Localized optogenetic targeting of rotors in atrial cardiomyocyte monolayers'
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Localized optogenetic targeting of rotors in atrial cardiomyocyte monolayers
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- Journal Article
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Islands of spatially discordant APD alternans underlie arrhythmogenesis by promoting electrotonic dyssynchrony in models of fibrotic rat ventricular myocardium
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A mathematical model of neonatal rat atrial monolayers with constitutively active acetylcholine-mediated K+ current
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- Journal Article
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Constitutively active acetylcholine-dependent potassium current increases atrial defibrillation threshold by favoring post-shock re-initiation
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Decreased repolarization reserve increases defibrillation threshold by favoring early afterdepolarizations in an in silico model of human ventricular tissue
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Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes
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Prolongation of minimal action potential duration in sustained fibrillation decreases complexity by transient destabilization