Ghent University Academic Bibliography

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Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

Hanne Verschuere (UGent) , Sabah Kasmi (UGent) , Lutz Nuhn (UGent) , Sènan Mickaël D'Almeida, Qiwen Zhu, Zifu Zhong (UGent) , Sandy Adjemian Catani (UGent) , Benoit Louage (UGent) , Jana De Vrieze, Haijun Yu, et al.

(2025) RSC ADVANCES. 15(15). p.11662-11674
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A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Zifu Zhong (UGent) , Marie Deventer (UGent) , Yong Chen (UGent) , Stijn Vanhee (UGent) , Inés Lammens (UGent) , Kim Deswarte (UGent) , Yi Huang (UGent) , Tingting Ye (UGent) , Haixiu Wang (UGent) , Lutz Nuhn, et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(7).
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PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

Alina G. Heck, Carolina Medina-Montano, Zifu Zhong (UGent) , Kim Deswarte (UGent) , Katharina Eigen, Judith Stickdorn, Johannes Kockelmann, Maximilian Scherger, Niek Sanders (UGent) , Stefan Lienenklaus, et al.

(2024) ADVANCED HEALTHCARE MATERIALS. 13(32).
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pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages

Leonard Kaps, Anne Huppertsberg, Niklas Choteschovsky, Adrian Klefenz, Feyza Durak, Babara Schrörs, Mustafa Diken, Emma Eichler, Sebastian Rosigkeit, Sascha Schmitt, et al.

(2022) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 119(12).
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Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles

Jana De Vrieze, Antonio Pires da Silva Baptista (UGent) , Lutz Nuhn, Simon Van Herck (UGent) , Kim Deswarte (UGent) , Haijun Yu, Bart Lambrecht (UGent) and Bruno De Geest (UGent)

(2021) ADVANCED THERAPEUTICS. 4(8).
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Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn (UGent) , Simon Van Herck (UGent) , Lutz Nuhn, Kim Deswarte (UGent) , Zifu Zhong (UGent) , et al.

(2021) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 60(17). p.9467-9473
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Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Anne Huppertsberg, Leonard Kaps, Zifu Zhong (UGent) , Sascha Schmitt, Judith Stickdorn, Kim Deswarte (UGent) , Francis Combes (UGent) , Christian Czysch, Jana De Vrieze, Sabah Kasmi (UGent) , et al.

(2021) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 143(26). p.9872-9883
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Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent

Jana De Vrieze, Simon Van Herck (UGent) , Lutz Nuhn (UGent) and Bruno De Geest (UGent)

(2020) MACROMOLECULAR RAPID COMMUNICATIONS. 41(18).
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Control over imidazoquinoline immune stimulation by pH-degradable poly(norbornene) nanogels

Johannes Kockelmann, Judith Stickdorn, Sabah Kasmi (UGent) , Jana De Vrieze, Michaela Pieszka, David Yuen W. Ng, Sunil A. David, Bruno De Geest (UGent) and Lutz Nuhn

(2020) BIOMACROMOLECULES. 21(6). p.2246-2257
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Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment

Ruben De Coen (UGent) , Lutz Nuhn, Chamani Perera, Maria Arista-Romero, Martijn Risseeuw (UGent) , Alec Freyn, Raffael Nachbagauer, Lorenzo Albertazzi, Serge Van Calenbergh (UGent) , David A. Spiegel, et al.

(2020) BIOMACROMOLECULES. 21(2). p.793-802

Academic Bibliography

Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages

Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles

Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent

Control over imidazoquinoline immune stimulation by pH-degradable poly(norbornene) nanogels

Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment

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