Ghent University Academic Bibliography

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2-((3,5-Dinitrobenzyl)thio)quinazolinones : potent antimycobacterial agents activated by deazaflavin (F420)-dependent nitroreductase (Ddn)

Yanlin Jian, He Eun Forbes, Fabian Hulpia (UGent) , Martijn Risseeuw (UGent) , Guy Caljon, Hélène Munier-Lehmann, Helena I. M. Boshoff and Serge Van Calenbergh (UGent)

(2021) JOURNAL OF MEDICINAL CHEMISTRY. 64(1). p.440-457
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Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors

Lijun Song (UGent) , Romain Merceron (UGent) , Fabian Hulpia (UGent) , Ainhoa Lucia, Begona Gracia, Yanlin Jian, Martijn Risseeuw (UGent) , Toon Verstraelen (UGent) , Paul Cos, Jose A. Ainsa, et al.

(2021) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 225.
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Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents

Yanlin Jian, Fabian Hulpia (UGent) , Martijn Risseeuw (UGent) , He Eun Forbes, Hélène Munier-Lehmann, Guy Caljon, Helena I. M. Boshoff and Serge Van Calenbergh (UGent)

(2020) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 201.
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- Journal Article
- A1
- open access
1-(1-Arylethylpiperidin-4-yl)thymine analogs as antimycobacterial TMPK inhibitors

Yanlin Jian, Fabian Hulpia (UGent) , Martijn Risseeuw (UGent) , He Eun Forbes, Guy Caljon, Hélène Munier-Lehmann, Helena I. M. Boshoff and Serge Van Calenbergh (UGent)

(2020) MOLECULES. 25(12).
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- Journal Article
- A1
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Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents

Yanlin Jian, Romain Merceron (UGent) , Steven De Munck (UGent) , He Eun Forbes, Fabian Hulpia (UGent) , Martijn Risseeuw (UGent) , Kristof Van Hecke (UGent) , Savvas Savvides (UGent) , Hélène Munier-Lehmann, Helena I. M. Boshoff, et al.

(2020) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 206.
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Structure guided lead generation toward nonchiral M. tuberculosis thymidylate kinase inhibitors

Lijun Song (UGent) , Romain Merceron (UGent) , Begoña Gracia, Ainhoa Lucía Quintana, Martijn Risseeuw (UGent) , Fabian Hulpia (UGent) , Paul Cos, José A Aínsa, Hélène Munier-Lehmann, Savvas Savvides (UGent) , et al.

(2018) JOURNAL OF MEDICINAL CHEMISTRY. 61(7). p.2753-2775
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- Conference Paper
- C3
- open access
The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

Lijun Song (UGent) , Martijn Risseeuw (UGent) , Fabian Hulpia (UGent) , Hélène Munier-Lehmann and Serge Van Calenbergh (UGent)

(2016) ChemCYS book of abstracts.
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- Conference Paper
- C3
The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

Lijun Song (UGent) , Martijn Risseeuw (UGent) , Fabian Hulpia (UGent) , Romain Merceron (UGent) , Savvas Savvides (UGent) , Hélène Munier-Lehmann and Serge Van Calenbergh (UGent)

(2016) Nucleosides, Nucleotides and Nucleic Acids, XXII Round table, Abstracts. p.180-180
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Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

Lijun Song (UGent) , Martijn Risseeuw (UGent) , Matheus Froeyen, Izet Karalic (UGent) , Jan Goeman (UGent) , Davie Cappoen, Johan Van der Eycken (UGent) , Paul Cos, Hélène Munier-Lehmann and Serge Van Calenbergh (UGent)

(2016) BIOORGANIC & MEDICINAL CHEMISTRY. 24(21). p.5172-5182
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The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

Lijun Song (UGent) , Martijn Risseeuw (UGent) , Fabian Hulpia (UGent) , Hélène Munier-Lehmann and Serge Van Calenbergh (UGent)

(2015) Frontiers in Medicinal Chemistry, Abstracts. p.254-254

Academic Bibliography

2-((3,5-Dinitrobenzyl)thio)quinazolinones : potent antimycobacterial agents activated by deazaflavin (F420)-dependent nitroreductase (Ddn)

Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors

Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents

1-(1-Arylethylpiperidin-4-yl)thymine analogs as antimycobacterial TMPK inhibitors

Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents

Structure guided lead generation toward nonchiral M. tuberculosis thymidylate kinase inhibitors

The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

The design and synthesis of inhibitors of Mycobacterium tuberculosis thymidylate kinase (MtTMPK)

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