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- 2017
- Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound
- 2016
- Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function
- 2015
- Physiology-based IVIVE predictions of tramadol from in vitro metabolism data
- Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation
- 2013
- Non-invasive method to obtain blood curves of 99mTc-mebrofenin
- 99mTc-mebrofenin disposition in chimeric mice with a humanized liver
- In vivo visualization and quantification of (disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice
- 2012
- Molecular imaging as a non-invasive tool to visualize impaired hepatobiliary transporter function in Oatp1a/1b and Mrp2 knock-out mice
- 2011
- In vivo µSPECT visualization of transport-mediated hepatic uptake and efflux of 99mTc-mebrofenin, and inhibition thereof with rifampicin
- 1986
- Direct assay for phosphotransacetylase and acetyl-coenzyme a carboxylase by high-performance liquid chromatography