Ghent University Academic Bibliography

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Impact of pre-existing anti-replicase immunity on the efficacy of self-amplifying mRNA vaccines

Xiaole Cui (UGent) , Laura Amelinck (UGent) , Oriane Gillon (UGent) , João Paulo Portela Catani, Ya Gao (UGent) , Qing Sun (UGent) , Elisabeth De Sutter (UGent) , Pieter Vervaeke (UGent) , Janne Snoeck (UGent) , Stefan Lienenklaus, et al.

(2025) Nature Communications. 17(1).
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A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Zifu Zhong (UGent) , Marie Deventer (UGent) , Yong Chen (UGent) , Stijn Vanhee (UGent) , Inés Lammens (UGent) , Kim Deswarte (UGent) , Yi Huang (UGent) , Tingting Ye, Haixiu Wang, Lutz Nuhn, et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(7).
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Amplification of protein expression by self-amplifying mRNA delivered in lipid nanoparticles containing a β-aminoester ionizable lipid correlates with reduced innate immune activation

Emily De Lombaerde, Xiaole Cui (UGent) , Yong Chen (UGent) , Zifu Zhong (UGent) , Julie Deckers (UGent) , Giulia Mencarelli, Lisa Opsomer (UGent) , Haixiu Wang, Jamie De Baere (UGent) , Stefan Lienenklaus, et al.

(2024) ACS NANO. 18(41). p.28311-28324
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PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

Alina G. Heck, Carolina Medina-Montano, Zifu Zhong (UGent) , Kim Deswarte (UGent) , Katharina Eigen, Judith Stickdorn, Johannes Kockelmann, Maximilian Scherger, Niek Sanders (UGent) , Stefan Lienenklaus, et al.

(2024) ADVANCED HEALTHCARE MATERIALS. 13(32).
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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Tingting Ye, Zifu Zhong (UGent) , Federica Cappellesso, Kim Deswarte (UGent) , Yong Chen (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Mark Gontsarik (UGent) , Stefan Lienenklaus, Dorien Van Lysebetten, et al.

(2024) BIOMATERIALS. 311.
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Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte Wallaeys (UGent) , Natalia Garcia Gonzalez (UGent) , Steven Timmermans (UGent) , Jolien Vandewalle (UGent) , Tineke Vanderhaeghen (UGent) , Somara De Beul (UGent) , Hester Dufoor (UGent) , Melanie Eggermont (UGent) , Elise Moens (UGent) , Victor Bosteels, et al.

(2024) CELL HOST & MICROBE. 32(10). p.1725-1743
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Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Alexander Lamoot, Sonia Jangra, Gabriel Laghlali, Prajakta Warang, Gagandeep Singh, Lauren A. Chang, Seok‐Chan Park, Gagandeep Singh, Kim Deswarte (UGent) , Zifu Zhong (UGent) , et al.

(2024) SMALL. 20(10).
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Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue

Zifu Zhong (UGent) , Yong Chen (UGent) , Kim Deswarte (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Xiaole Cui (UGent) , Simon Van Herck (UGent) , Tingting Ye, Mark Gontsarik (UGent) , Stefan Lienenklaus, et al.

(2023) ADVANCED HEALTHCARE MATERIALS. 12(32).
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Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu Zhong (UGent) , Séan Mc Cafferty, Lisa Opsomer (UGent) , Haixiu Wang, Hanne Huysmans, Joyca De Temmerman, Stefan Lienenklaus, João Portela Catani (UGent) , Francis Combes (UGent) and Niek Sanders (UGent)

(2021) MOLECULAR THERAPY. 29(4). p.1370-1381
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Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte (UGent) , Kaloian Koynov, Bianka Golba, Tingting Ye, Zifu Zhong (UGent) , Sabah Kasmi (UGent) , Alexander Lamoot, Yong Chen (UGent) , et al.

(2021) ACS APPLIED MATERIALS & INTERFACES. 13(5). p.6011-6022

Academic Bibliography

Impact of pre-existing anti-replicase immunity on the efficacy of self-amplifying mRNA vaccines

A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Amplification of protein expression by self-amplifying mRNA delivered in lipid nanoparticles containing a β-aminoester ionizable lipid correlates with reduced innate immune activation

PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Lipid-polyglutamate nanoparticle vaccine platform

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