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Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment.
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VSIG4-expressing macrophages contribute to antiparasitic and antimetastatic responses in the peritoneal cavity
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A single-cell transcriptomic map of the murine and human multiple myeloma immune microenvironment across disease stages
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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity
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Hapten/myristoyl functionalized poly(propyleneimine) dendrimers as potent cell surface recruiters of antibodies for mediating innate immune killing
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Macrophages are metabolically heterogeneous within the tumor microenvironment
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Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation
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IL1 beta promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D
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Therapeutic depletion of CCR8(+) tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
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Myeloid cell heterogeneity in cancer: not a single cell alike