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Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target NaV1.7
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Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri
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Pharmacological characterisation of the highly Nav1.7 selective spider venom peptide Pn3a
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Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami
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Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix
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Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
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The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop
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Seven novel modulators of the analgesic target Nav1.7 uncovered using a high-throughput venom-based discovery approach
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A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a
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The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels