Ghent University Academic Bibliography

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A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases

Yanina Jansen, Vibeke Kruse (UGent) , Jurgen Corthals, Kelly Schats, Pieter-Jan van Dam, Teofila Seremet, Carlo Heirman, Lieve Brochez (UGent) , Mark Kockx, Kris Thielemans, et al.

(2020) CANCER IMMUNOLOGY IMMUNOTHERAPY. 69(12). p.2589-2598
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Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Patrick Tjok Joe, Ioanna Christopoulou (UGent) , Lien Van Hoecke (UGent) , Bert Schepens (UGent) , Tine Ysenbaert (UGent) , Carlo Heirman, Kris Thielemans, Xavier Saelens (UGent) and Joeri Aerts

(2019) JOURNAL OF TRANSLATIONAL MEDICINE. 17.
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Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Willem Staels (UGent) , Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco de Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, et al.

(2018) DIABETOLOGIA. 61(8). p.1804-1810
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Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Kevin Van der Jeught, Stefaan De Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, Federico Perche, Sarah Maenhout, Sanne Bevers, Katrijn Broos, Kim Deswarte (UGent) , et al.

(2018) ACS NANO. 12(10). p.9815-9829
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Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

Katrijn Broos, Kevin Vanderjeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Kris Thielemans and Karine Breckpot

(2016) MOLECULAR THERAPY-NUCLEIC ACIDS. 5.
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The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Yannick Willemen, Johan M. J. Van den Bergh, Sarah Bonte (UGent) , Sebastien Anguille, Carlo Heirman, Barbara MH Stein, Herman Goossens, Tessa Kerre (UGent) , Kris Thielemans, Marc Peeters, et al.

(2016) ONCOTARGET. 7(45). p.73960-73970
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Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Lode Goethals, Sarah Maenhout, Daphné Benteyn, Cleo Goyvaerts, Stephanie Dufour, Kevin Van Der Jeught, Lukasz Bialkowski, et al.

(2016) CANCER IMMUNOLOGY RESEARCH. 4(2). p.146-156
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The ReNAissanCe of mRNA-based cancer therapy

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Heleen Dewitte (UGent) , Ine Lentacker (UGent) , Carlo Heirman, Karine Breckpot and Kris Thielemans

(2015) EXPERT REVIEW OF VACCINES. 14(2). p.235-251
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Targeting the tumor microenvironment to enhance antitumor immune responses

Kevin Van Der Jeught, Lukasz Bialkowski, Lidia Daszkiewicz, Katrijn Broos, Cleo Goyvaerts, Dries Renmans, Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans and Karine Breckpot

(2015) ONCOTARGET. 6(3). p.1359-1381
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The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans, Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 194. p.28-36

Academic Bibliography

A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

The ReNAissanCe of mRNA-based cancer therapy

Targeting the tumor microenvironment to enhance antitumor immune responses

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

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