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Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment.
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VSIG4-expressing macrophages contribute to antiparasitic and antimetastatic responses in the peritoneal cavity
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Depleting IL1R2+ tumor-infiltrating regulatory T cells with an ADCC-prone nanobody construct boosts the efficacy of anti-PD-1 immunotherapy
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Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells
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Myeloid tumor necrosis factor and heme oxygenase-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion
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- A1
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Macrophages are metabolically heterogeneous within the tumor microenvironment
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IL1 beta promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D
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Therapeutic depletion of CCR8(+) tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
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STAT6 mediates footpad immunopathology in the absence of IL-12p40 following infection of susceptible BALB/c mice with Leishmania major
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M-CSF and GM-CSF receptor signaling differentially regulate monocyte maturation and macrophage polarization in the tumor microenvironment