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A critical Blimp-1-dependent IL-10 regulatory pathway in T cells protects from a lethal pro-inflammatory cytokine storm during acute experimental Trypanosoma brucei Infection
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- Journal Article
- A1
- open access
Trypanosoma brucei co-opts NK cells to kill splenic B2 B cells
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Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments
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Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis
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Unravelling the events leading to inflammation-induced trypanosomiasis-associated acute anemia
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Two unique IL-10 producing B cell subsets contribute to the host cytokine balance during Trypanosoma brucei infections
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- Journal Article
- A2
- open access
Acute disruption of bone marrow B lymphopoiesis and apoptosis of transitional and marginal zone B cells in the spleen following a blood-stage Plasmodium chabaudi infection in mice
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T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis
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The central role of macrophages in trypanosomiasis-associated anemia : rationale for therapeutical approaches
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Parasite-induced B-cell apoptosis results in loss of specific protective anti-trypanosome antibody responses, and abolishment of vaccine induced protective memory responses.