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Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury
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Mechanisms and in vitro models of drug-induced cholestasis
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Connexin and pannexin (hemi)channels : emerging targets in the treatment of liver disease
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Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound
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Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects : a stable isotope study
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- Journal Article
- A1
- open access
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data
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Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation
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Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido[3,2-b]azepin-6-one
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Synthesis of a novel scaffold, 4-trifluoromethyl-tetrahydro-6H-pyrido[3,2-b]azepin-6-one