Ghent University Academic Bibliography

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Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

Eva Gijbels, Vânia Vilas‐Boas, Pieter Annaert, Tamara Vanhaecke, Lindsey Devisscher (UGent) and Mathieu Vinken

(2020) ARCHIVES OF TOXICOLOGY. 94(4). p.1151-1172
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Mechanisms and in vitro models of drug-induced cholestasis

Eva Gijbels, Vânia Vilas-Boas, Neel Deferm, Lindsey Devisscher (UGent) , Hartmut Jaeschke, Pieter Annaert and Mathieu Vinken

(2019) ARCHIVES OF TOXICOLOGY. 93(5). p.1169-1186
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- Journal Article
- A1
Connexin and pannexin (hemi)channels : emerging targets in the treatment of liver disease

Axelle Cooreman, Raf van Campenhout, Steven Ballet, Pieter Annaert, Bert Van Den Bossche, Isabelle Colle (UGent) , Bruno Cogliati and Mathieu Vinken

(2019) HEPATOLOGY. 69(3). p.1317-1323
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Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound

Huybrecht T'jollyn (UGent) , Jan Snoeys, Jan Van Bocxlaer (UGent) , Lies De Bock, Pieter Annaert, Achiel Van Peer, Karel Allegaert, Geert Mannens, An Vermeulen (UGent) and Koen Boussery (UGent)

(2017) EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 42(3). p.537-543
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Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects : a stable isotope study

Eef Boets, Sara V Gomand, Lise Deroover, Tom Preston, Karen Vermeulen (UGent) , Vicky De Preter, Henrike M Hamer, Guy Van den Mooter, Luc De Vuyst, Christophe M Courtin, et al.

(2017) JOURNAL OF PHYSIOLOGY-LONDON. 595(2). p.541-555
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- Journal Article
- A1
- open access
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data

Huybrecht T'jollyn (UGent) , Jan Snoeys, Pieter Colin (UGent) , Jan Van Bocxlaer (UGent) , Pieter Annaert, Filip Cuyckens, An Vermeulen (UGent) , Achiel Van Peer, Karel Allegaert, Geert Mannens, et al.

(2015) PHARMACEUTICAL RESEARCH. 32(1). p.260-274
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Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation

Huybrecht T'jollyn (UGent) , Jan Snoeys, An Vermeulen (UGent) , Robin Michelet (UGent) , Filip Cuykens, Geert Mannens, Achiel Van Peer, Pieter Annaert, Karel Allegaert, Jan Van Bocxlaer (UGent) , et al.

(2015) AAPS JOURNAL. 17(6). p.1376-1387
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Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Koen Muylaert (UGent) , Martyna Jatczak (UGent) , Benjamin Wuyts (UGent) , Laurens De Coen, Kristof Van Hecke (UGent) , Hans Loones, Janneke Keemink, Daniel Garcia Jimenez (UGent) , Sven Mangelinckx (UGent) , Pieter Annaert, et al.

(2014) SYNLETT. 25(10). p.1443-1447
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- Conference Paper
- C3
Synthesis of a novel scaffold, 4-trifluoromethyl-tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Koen Muylaert (UGent) , Martyna Jatczak (UGent) , Benjamin Wuyts (UGent) , Laurens M De Coen, Hans Loones, Janneke Keemink, Daniel Garcia Jimenez (UGent) , Sven Mangelinckx (UGent) , Kristof Van Hecke (UGent) , Pieter Annaert, et al.

(2014) Portugese Young Chemist Meeting, Abstracts.

Academic Bibliography

Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

Mechanisms and in vitro models of drug-induced cholestasis

Connexin and pannexin (hemi)channels : emerging targets in the treatment of liver disease

Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects : a stable isotope study

Physiology-based IVIVE predictions of tramadol from in vitro metabolism data

Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation

Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Synthesis of a novel scaffold, 4-trifluoromethyl-tetrahydro-6H-pyrido[3,2-b]azepin-6-one

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