Ghent University Academic Bibliography

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Systematic investigation of lipophilicity modulation by aliphatic fluorination motifs

Benjamin Jeffries, Zhong Wang, Hannah R. Felstead, Jean-Yves Le Questel, James S. Scott, Elisabetta Chiarparin, Jerome Graton and Bruno Linclau (UGent)

(2020) JOURNAL OF MEDICINAL CHEMISTRY. 63(3). p.1002-1031
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Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups

Benjamin Jeffries, Zhong Wang, Robert Troup, Anais Goupille, Jean-Yves Le Questel, Charlene Fallan, James S. Scott, Elisabetta Chiarparin, Jerome Graton and Bruno Linclau (UGent)

(2020) BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 16. p.2141-2150
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Synthesis of 2,3,4-trideoxy-2,3,4-trifluoroglucose

Lucas Quiquempoix, Zhong Wang, Jerome Graton, Peter G. Latchem, Mark Light, Jean-Yves Le Questel and Bruno Linclau (UGent)

(2019) JOURNAL OF ORGANIC CHEMISTRY. 84(9). p.5899-5906
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3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-alpha-GalCer analogues : synthesis and biological evaluation on human iNKT cells stimulation

Samuel Golten, Allan Patinec, Katy Akoumany, Jezabel Rocher, Jerome Graton, Denis Jacquemin, Jean-Yves Le Questel, Arnaud Tessier, Jacques Lebreton, Virginie Blot, et al.

(2019) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 178. p.195-213
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Reducing the lipophilicity of perfluoroalkyl groups by CF2-F/CF2-Me or CF3/CH3 exchange

Benjamin Jeffries, Zhong Wang, Jerome Graton, Simon D. Holland, Thomasin Brind, Ryan D. R. Greenwood, Jean-Yves Le Questel, James S. Scott, Elisabetta Chiarparin and Bruno Linclau (UGent)

(2018) JOURNAL OF MEDICINAL CHEMISTRY. 61(23). p.10602-10618
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A study of intramolecular hydrogen bonding in levoglucosan derivatives

Lucas Quiquempoix, Elena Bogdan, Neil J. Wells, Jean-Yves Le Questel, Jerome Graton and Bruno Linclau (UGent)

(2017) MOLECULES. 22(4).
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Influence of alcohol beta-fluorination on hydrogen-bond acidity of conformationally flexible substrates

Jerome Graton, Guillaume Compain, Francois Besseau, Elena Bogdan, Joseph M. Watts, Lewis Mtashobya, Zhong Wang, Alex Weymouth-Wilson, Nicolas Galland, Jean-Yves Le Questel, et al.

(2017) CHEMISTRY-A EUROPEAN JOURNAL. 23(12). p.2811-2819
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alpha-fluoro-o-cresols : the key role of intramolecular hydrogen bonding in conformational preference and hydrogen-bond acidity

Elena Bogdan, Alexis Quarre de Verneuil, Francois Besseau, Guillaume Compain, Bruno Linclau (UGent) , Jean-Yves Le Questel and Jerome Graton

(2016) CHEMPHYSCHEM. 17(17). p.2702-2709
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Influence of fluorination on the conformational properties and hydrogen-bond acidity of benzyl alcohol derivatives

Elena Bogdan, Guillaume Compain, Lewis Mtashobya, Jean-Yves Le Questel, Francois Besseau, Nicolas Galland, Bruno Linclau (UGent) and Jerome Graton

(2015) CHEMISTRY-A EUROPEAN JOURNAL. 21(32). p.11462-11474
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Intramolecular OH⋅⋅⋅fluorine hydrogen bonding in saturated, acyclic fluorohydrins : the γ-fluoropropanol motif

Bruno Linclau (UGent) , Florent Peron, Elena Bogdan, Neil Wells, Zhong Wang, Guillaume Compain, Clement Q. Fontenelle, Nicolas Galland, Jean-Yves Le Questel and Jerome Graton

(2015) CHEMISTRY-A EUROPEAN JOURNAL. 21(49). p.17808-17816

Academic Bibliography

Systematic investigation of lipophilicity modulation by aliphatic fluorination motifs

Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups

Synthesis of 2,3,4-trideoxy-2,3,4-trifluoroglucose

3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-alpha-GalCer analogues : synthesis and biological evaluation on human iNKT cells stimulation

Reducing the lipophilicity of perfluoroalkyl groups by CF2-F/CF2-Me or CF3/CH3 exchange

A study of intramolecular hydrogen bonding in levoglucosan derivatives

Influence of alcohol beta-fluorination on hydrogen-bond acidity of conformationally flexible substrates

alpha-fluoro-o-cresols : the key role of intramolecular hydrogen bonding in conformational preference and hydrogen-bond acidity

Influence of fluorination on the conformational properties and hydrogen-bond acidity of benzyl alcohol derivatives

Intramolecular OH⋅⋅⋅fluorine hydrogen bonding in saturated, acyclic fluorohydrins : the γ-fluoropropanol motif

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