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Quantification of egg ovalbumin hydrolysate-derived anti-hypertensive peptides in an in vitro model combining luminal digestion with intestinal Caco-2 cell transport
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Gastrointestinal simulation model TWIN-SHIME shows differences between human urolithin-metabotypes in gut microbiota composition, pomegranate polyphenol metabolism, and transport along the intestinal tract
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Anti-inflammatory potential of black carrot (Daucus carota L.) polyphenols in a co-culture model of intestinal Caco-2 and endothelial EA.hy926 cells
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- Journal Article
- A1
- open access
Ferulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice
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Egg-derived bioactive peptides with ACE-inhibitory properties : a literature update
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Aronia (Aronia melanocarpa) phenolics bioavailability in a combined in vitro digestion/Caco-2 cell model is structure and colon region dependent
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Quercetin mitigates valinomycin-induced cellular stress via stress-induced metabolism and cell uptake
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Flavonoid–gastrointestinal mucus interaction and its potential role in regulating flavonoid bioavailability and mucosal biophysical properties
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Extraction and bioconversion of kaempferol metabolites from cauliflower outer leaves through fungal fermentation
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Collision cross section prediction of deprotonated phenolics in a travelling-wave ion mobility spectrometer using molecular descriptors and chemometrics
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Flow cytometric method for the detection of flavonoids in cell lines
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Metabolism of quercetin and naringenin by food-grade fungal inoculum, Rhizopus azygosporus Yuan et Jong (ATCC 48108)
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Flavonoids : evidence for inhibitory effects against obesity and their possible mechanisms of action
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Flavonoids stimulate cholecystokinin peptide secretion from the enteroendocrine STC-1 cells
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- Journal Article
- A1
- open access
Resveratrol improves TNF-α-induced endothelial dysfunction in a coculture model of a Caco-2 with an endothelial cell line
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Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure–activity/property relationship-based approach in the study of bioavailability and bioactivity
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Review on the use of cell cultures to study metabolism, transport, and accumulation of flavonoids: from mono-cultures to co-culture systems
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Analysis of interaction of phenolic compounds with the cholecystokinin signaling pathway to explain effects on reducing food intake
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Development of a CCK1R-membrane nanoparticle as a fish-out tool for bioactive peptides
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Two- and three-dimensional quantitative structure–permeability relationship of flavonoids in Caco-2 cells using stepwise multiple linear regression (SMLR), partial least squares regression (PLSR), and pharmacophore (GALAHAD)-based comparative molecular similarity index analysis (COMSIA)
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Use of metabolomics and fluorescence recovery after photobleaching to study the bioavailability and intestinal mucus diffusion of polyphenols from cauliflower waste
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Liquid chromatography–mass spectrometry coupled with multivariate analysis for the characterization and discrimination of extractable and nonextractable polyphenols and glucosinolates from red cabbage and Brussels sprout waste streams
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Combined alkaline hydrolysis and ultrasound-assisted extraction for the release of nonextractable phenolics from cauliflower (Brassica oleracea var. botrytis) waste
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Enzyme-assisted extraction enhancing the phenolic release from cauliflower (Brassica oleracea L. var. botrytis) outer leaves
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Angiotensin-converting enzyme inhibitory effects by plant phenolic compounds
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- Journal Article
- A1
- open access
Improved release and metabolism of flavonoids by steered fermentation processes: a review
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Quantitative structure (inhibitory) activity relationship and molecular docking studies of phenolic acids to angiotensin-converting enzyme
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Analysis of interaction of phenolic compounds with the cholecystokinin signaling pathway to explain effects on reducing food intake
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Ultra(high)-pressure liquid chromatography-electrospray ionization-time-of-flight-ion mobility-high definition mass spectrometry for the rapid identification and structural characterization of flavonoid glycosides from cauliflower waste
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Angiotensin-converting enzyme inhibitory effects by plant phenolic compounds: a study of structure activity relationships
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Protein-derived bioactives affecting CCK-induced satiety: how to detect untargeted compounds and determine their identity
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- Journal Article
- A1
- open access
Time-resolved quantitative analysis of CCK1 receptor-induced intracellular calcium increase
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- Journal Article
- A1
- open access
Screening of soy and milk protein hydrolysates for their ability to activate the CCK1 receptor
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- Journal Article
- A1
- open access
Antihypertensive effect of insect cells: in vitro and in vivo evaluation
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The CCK(-like) receptor in the animal kingdom: functions, evolution and structures
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Angiotensin I-converting enzyme inhibitory activity of gelatin hydrolysates and identification of bioactive peptides
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Screening tool for bioactive peptides with CCK1R activity
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Cell-based bioassay to screen for bioactive peptides with CCK1 receptor activity
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Screening of protein hydrolysates for their potential to activate the CCK1 receptor
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Comparison of two techniques to measure a CCK1-receptor induced intracellular calcium increase
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Ala-Val-Phe and Val-Phe: in vitro ACE inhibitory peptides derived from insect protein with antihypertensive activity in spontaneously hypertensive rats
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Bioactive peptides with CCK1-receptor activity as an aid in the battle against obesity
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Critical evaluation of the use of bioinformatics as a theoretical tool to find high-potential sources of ACE inhibitory peptides
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Antioxidative and ACE inhibitory activities in enzymatic hydrolysates of the cotton leafworm, Spodoptera littoralis
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Production and enrichment of bioactive peptides derived from milk proteins
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Bio-active peptides in food proteins
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Effect of ACE inhibitors and TMOF on growth, development and trypsin activity of larval Spodoptera littoralis
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Angiotensin converting enzyme in Spodoptera littoralis: molecular characterization, expression and activity profile during development
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Purification and identification of an angiotensin I converting enzyme (ACE) inhibitory peptide from the gastrointestinal hydrolysate of the cotton leafworm, Spodoptera littoralis
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Antihypertensive mechanism of the dipeptide Val-Tyr in rat aorta
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Presence of angiotensin converting enzyme isoforms in larval lepidoptera (Spodoptera littoralis)
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In vitro evaluation of antihypertensive mechanism of the dipeptide Val-Tyr in rat aorta organ bath experiments
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ACE inhibitor captopril reduces ecdysteroids and oviposition in moths
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Melk tegen hoge bloeddruk
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ACE inhibitory activity in enzymatic hydrolysates of insect protein
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ACE inhibitory peptides derived from enzymatic hydrolysates of animal muscle protein: A review
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The angiotensin converting enzyme inhibitor captopril reduces oviposition and ecdysteroid levels in Lepidoptera
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ACE inhibitory activity from insects after enzymatic hydrolysis