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- Journal Article
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Sequence-defined antibody-recruiting macromolecules
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- Journal Article
- A1
- open access
Visible light conjugation with triazolinediones as a route to degradable poly(ethylene glycol)-lipids for mRNA lipid nanoparticle formulation
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- Journal Article
- A1
- open access
LXR signaling controls homeostatic dendritic cell maturation
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- Journal Article
- A1
- open access
A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment
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Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity
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- Journal Article
- A1
- open access
Towards a rational design of antibody‐recruiting molecules through a computational microscopy view of their interactions with the target antibody
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Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions
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- Journal Article
- A1
- open access
Hapten/myristoyl functionalized poly(propyleneimine) dendrimers as potent cell surface recruiters of antibodies for mediating innate immune killing
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Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue
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- Journal Article
- A1
- open access
Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids
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- Journal Article
- A1
- open access
pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages
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An intelligent nanovehicle armed with multifunctional navigation for precise delivery of toll‐like receptor 7/8 agonist and immunogenic cell death amplifiers to eliminate solid tumors and trigger durable antitumor immunity
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In situ tumor vaccination with calcium‐linked degradable coacervate nanocomplex co‐delivering photosensitizer and TLR7/8 agonist to trigger effective anti‐tumor immune responses
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Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables
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Delivery routes matter : safety and efficacy of intratumoral immunotherapy
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Lipid-polyglutamate nanoparticle vaccine platform
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Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**
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- Journal Article
- A1
- open access
Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators
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- Journal Article
- A1
- open access
Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles
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Biomaterials applications of cyclic polymers
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- Journal Article
- A1
- open access
Covalent cell surface conjugation of nanoparticles by a combination of metabolic labeling and click chemistry
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Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment
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- Journal Article
- A1
- open access
Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent
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- Journal Article
- A1
- open access
Multivalent antibody-recruiting macromolecules : linking increased binding affinity with enhanced innate immune killing
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- Miscellaneous
- open access
Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine
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Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles
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- Journal Article
- A1
- open access
Zebrafish embryos allow prediction of nanoparticle circulation times in mice and facilitate quantification of nanoparticle-cell interactions
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- Journal Article
- A1
- open access
Control over imidazoquinoline immune stimulation by pH-degradable poly(norbornene) nanogels
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- Journal Article
- A1
- open access
Current status of COVID-19 (pre)clinical vaccine development
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- Journal Article
- A1
- open access
Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy
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- Journal Article
- A1
- open access
Feasibility of mechanical extrusion to coat nanoparticles with extracellular vesicle membranes
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- Journal Article
- A1
- open access
Recombinant DnaK orally administered protects axenic European sea bass against vibriosis
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Prilling of API/fatty acid suspensions : screening of additives for drug release modification
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- Journal Article
- A1
- open access
ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids
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Tumor engineered model for low-grade serous ovarian carcinoma (LGSOC) : mimicking the tumor environment on a cellular and biophysical level
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Poly(2-ethyl-2-oxazoline) conjugates with salicylic acid via degradable modular ester linkages
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Poly(2-methyl-2-oxazoline) conjugates with doxorubicin : from synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties
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- Journal Article
- A1
- open access
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction
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- Journal Article
- A1
- open access
Efficient innate immune killing of cancer cells triggered by cell-surface anchoring of multivalent antibody-recruiting polymers
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Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo
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Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells
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Unexpected reactivity switch in the statistical copolymerization of 2-oxazolines and 2-oxazines enabling the one-step synthesis of amphiphilic gradient copolymers
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Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists
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- Journal Article
- A1
- open access
The future of layer-by-layer assembly : a tribute to ACS Nano associate editor Helmuth Möhwald
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Tumor engineered model for peritoneal metastasis with controllable stiffness
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Tumor engineered scaffolds recapitulate a human peritoneal tumor environment at the cellular and biophysical level
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A synthetic, transiently thermoresponsive homopolymer with UCST behaviour within a physiologically relevant window
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Prilling of API/fatty acid suspensions : processability and characterisation
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Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach
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Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses
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Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates
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The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses
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Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
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Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist
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Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties
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FRET monitoring of intracellular ketal hydrolysis in synthetic nanoparticles
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Transiently thermoresponsive acetal polymers for safe and effective administration of Amphotericin B as a vaccine adjuvant
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Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through strain promoted azide alkyne cycloaddition ligation
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Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity
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Recombinant ferritin-H induces immunosuppression in European sea bass larvae (Dicentrarchus labrax) rather than immunostimulation and protection against a Vibrio anguillarum infection
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Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue
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A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry : from chemical characterization to in vivo biodistribution
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Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models
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- Journal Article
- A1
- open access
pH-Sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated ester scaffolds : synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish
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The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)
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- Journal Article
- A1
- open access
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
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- Conference Paper
- C3
- open access
Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
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- Conference Paper
- C3
- open access
Heterocellular 3D scaffolds as biomimetic of peritoneal metastases
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Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
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Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
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Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs
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Tyrosine-triazolinedione bioconjugation as site-selective protein modification starting from RAFT-derived polymers
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Developments and future clinical outlook of taxane nanomedicines
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Amphiphilic ferrocene-containing PEG block copolymers as micellar nanocarriers and smart surfactants
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Transiently thermoresponsive polymers and their applications in biomedicine
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Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis
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- Journal Article
- A1
- open access
Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization
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- Journal Article
- A1
- open access
Uptake of long protein-polyelectrolyte nanotubes by dendritic cells
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Cancer cell lysate entrapment in CaCO3 engineered with polymeric TLR-agonists : immune-modulating microparticles in view of personalized antitumor vaccination
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Preparation and characterization of alginate microparticles containing a model protein for oral administration in gnotobiotic European sea bass (Dicentrarchus labrax) larvae
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Arginine-rich peptide-based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide
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- Journal Article
- A1
- open access
Polyelectrolyte-enrobed cancer cells in view of personalized immune-therapy
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Micellar paclitaxel-initiated RAFT polymer conjugates with acid-sensitive behavior
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- Journal Article
- A1
- open access
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12
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Immobilization of 2-deoxy-D-ribose-5-phosphate aldolase in polymeric thin films via the Langmuir-Schaefer technique
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Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery
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Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination
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Salt-driven deposition of thermoresponsive polymer-coated metal nanoparticles on solid substrates
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Poly(N-isopropylacrylamide) coated gold nanoparticles as colourimetric temperature and salt sensors
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- Conference Paper
- C3
- open access
NewTumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
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Engineering polymer hydrogel nanoparticles for lymph node-targeted delivery
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Transiently responsive block copolymer micelles based on N-(2-hydroxypropyl)methacrylamide engineered with hydrolyzable ethylcarbonate side chains
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Super resolution imaging of nanoparticles cellular uptake and trafficking
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- Journal Article
- A1
- open access
Hydrophilic thermoplastic polyurethanes for the manufacturing of highly dosed oral sustained release matrices via hot melt extrusion and injection molding
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- Journal Article
- A1
- open access
A generic polymer-protein ligation strategy for vaccine delivery
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- Journal Article
- A1
- open access
pH-Degradable mannosylated nanogels for dendritic cell targeting
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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation
(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(29). p.8098-8103 -
Well-defined polymer-paclitaxel prodrugs by a grafting-from-drug approach
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Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification
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Squaric ester amides as hydrolysis-resistant functional groups for protein-conjugation of RAFT-derived polymers
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Recombinant ferritin-H induces immunosupression in European sea bass larvae (Dicentrarchus labrax) rather than immunostmulation and protection against Vibrio anguillarum
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- Journal Article
- A1
- open access
pH-independent immediate release polymethacrylate formulations : an observational study
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- Journal Article
- A1
- open access
Duality of β-glucan microparticles: antigen carrier and immunostimulants
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- Conference Paper
- C3
- open access
Administration of bacterial heat shock protein 70 to induce a protective innate immune response in European sea bass larvae (Dicentrarchus labrax) against Vibrio anguillarum
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- Conference Paper
- C3
- open access
Recombinant ferritin-H induces immunosuppression in European sea bass larvae (Dicentrarchus labrax) rather than immunostimulation and protection against Vibrio anguillarum
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Linear polyethylenimine as (multi) functional initiator for organocatalytic L-lactide polymerization
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Acid-labile thermoresponsive copolymers that combine fast pH-triggered hydrolysis and high stability under neutral conditions
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Tailoring cellular uptake of gold nanoparticles via the hydrophilic-to-hydrophobic ratio of their (co)polymer coating
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Thermoresponsive polymer coated gold nanoparticles: from MADIX/RAFT copolymerization of N-vinylpyrrolidone and N-vinylcaprolactam to salt and temperature induced nanoparticle aggregation
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Solvent-free mechanochemical synthesis of a bicyclononyne tosylate: a fast route towards bioorthogonal clickable poly(2-oxazoline)s
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- Journal Article
- A1
- open access
Degradable ketal-based block copolymer nanoparticles for anticancer drug delivery : a systematic evaluation
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Rational design of a hexapeptide hydrogelator for controlled-release drug delivery
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Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
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Colorimetric logic gates based on poly(2-alkyl-2-oxazoline)coated gold nanoparticles
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One-pot preparation of inert well-defined polymers by RAFT polymerization and in situ end group transformation
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Transiently responsive protein–polymer conjugates via a 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators
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Polymer-protein conjugation via a 'grafting to' approach: a comparative study of the performance of protein-reactive RAFT chain transfer agents
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β-glucan microparticles targeted to epithelial APN as oral antigen delivery system
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Sequence-selective DNA recognition and enhanced cellular up-take by peptide–steroid conjugates
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- Conference Paper
- C3
- open access
β-glucan microparticles targeted to APN as mucosal antigen delivery system in oral vaccination of piglets against ETEC infections
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Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake
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The road to an immune-priming strategy: a case of gnotobiotic European sea bass (Dicentrarchus labrax) larvae
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- Conference Paper
- C1
- open access
Capsules changing in brittleness due to leaching of plasticizing agents
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Spray-dried polyelectrolyte microparticles in oral antigen delivery : stability, biocompatibility and cellular uptake
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Hydrogen bonded multilayer films based on poly(2-oxazoline)s and tannic acid
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Nanoporous polyelectrolyte vaccine microcarriers: a formulation platform for enhancing humoral and cellular immune responses
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Bio-hybrid tumor cell-templated capsules: a generic formulation strategy for tumor associated antigens in view of immune therapy
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Fast and accurate partial hydrolysis of poly(2-ethyl-2-oxazoline) into tailored linear polyethylenimine copolymers
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Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers
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Dual pH- and temperature-responsive RAFT-based block co-polymer micelles and polymer-protein conjugates with transient solubility
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Just spray it: LbL assembly enters a new age
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Straightforward RAFT procedure for the synthesis of heterotelechelic poly(acrylamide)s
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Micro-particle encapsulated carcinoma-associated fibroblast (CAF) deceive and redirect disseminated cancer cells
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Beta-glucan particles as novel antigen delivery systems: towards oral vaccination
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One-step spray-dried polyelectrolyte microparticles enhance the antigen cross-presentation capacity of porcine dendritic cells
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- Journal Article
- A1
- open access
Solvent-free drug crystal engineering for drug nano- and micro suspensions
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Beta-glucan particles as novel antigen delivery systems : towards oral vaccination
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- Conference Paper
- C3
- open access
Yeast particles targeted to APN as antigen delivery system to porcine immune cells
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- Conference Paper
- C3
- open access
Polyelectrolyte microparticles as biomimetic mucosal delivery vehicles facilitate antigen presentation by dendritic cells
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Gelucire 44/14 based immediate release formulations for poorly water-soluble drugs
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β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination
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Complexity from simplicity : unique polymer capsules, rods, monoliths, and liquid marbles prepared via HIPE in microfluidics
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Mechanical strength and intracellular uptake of CaCO₃- templated LbL capsules composed of biodegradable polyelectrolytes: the influence of the number of layers
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CAF-encapsulated mico-particels capture free cancer cells from the peritoneal fluid
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Microparticles delivery system in gnotobiotic European sea bass larvae (Dicentrarchus labrax, L. 1758)
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Improved anti-inflammatory effects in rabbit eye model using biodegradable poly beta-amino ester nanoparticles of triamcinolone acetonide
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Systematic processing of beta-tricalcium phosphate for efficient protein loading and in vitro analysis of antigen uptake
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Tunable self-assembled nanogels composed of well-defined thermoresponsive hyaluronic acid-polymer conjugates
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Hydrogen bonded polymeric multilayer films assembled below and above the cloud point temperature
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Magnetically engineered microcapsules as intracellular anchors for remote control over cellular mobility
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Structural modifications of polymethacrylates: impact on thermal behavior and release characteristics of glassy solid solutions
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- Journal Article
- A1
- open access
Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms
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- Journal Article
- A1
- open access
Formulation of poorly water-soluble drugs via coacervation : a pilot study using febantel
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Salt plays a pivotal role in the temperature-responsive aggregation and layer-by-layer assembly of polymer-decorated gold nanoparticles
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Polysaccharide-based responsive nanogels for controlled drug delivery
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Dual temperature- and pH-responsive polymers for protein conjugation and vaccine design
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Polymeric multilayer capsules for drug delivery
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Engineered (hep/pARG)2 polyelectrolyte capsules for sustained release of bioactive TGF-β1
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Engineered 3D microporous gelatin scaffolds to study cell migration
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Poly(2-ethyl-2-oxazoline) as matrix excipient for drug formulation by hot melt extrusion and injection molding
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Partial hydrolysis of poly(2-ethyl-2-oxazoline) and potential implications for biomedical applications?
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Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection
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Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function
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- Conference Paper
- C3
- open access
Biomimetic polyelectrolyte microparticles facilitate antigen presentation by porcine dendritic cells
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- Journal Article
- A1
- open access
Redox-responsive degradable PEG cryogels as potential cell scaffolds in tissue engineering
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Targeting aminopeptidase N, a newly identified receptor for F4ac fimbriae, enhances the intestinal mucosal immune response
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- Conference Paper
- C3
- open access
Single step spray-dried polyelectrolyte microparticles enhance the antigen cross-presentation capacity of porcine dendritic cells
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Crossing the barrier: targeting epithelial receptors for enhanced oral vaccine delivery
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Patchiness of embedded particles and film stiffness control through concentration of gold nanoparticles
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Interaction between polymeric multilayer capsules and immune cells
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Redox-responsive degradation of poly(ethylene glycol) (PEG) based cryogels
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Hydrophobic shell loading of biopolyelectrolyte capsules
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- Journal Article
- A1
- open access
Polymeric multilayer capsules delivering biotherapeutics
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Anisotropic multicompartment micro- and nano-capsules produced via embedding into biocompatible PLL/HA films
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Release properties of pressurized microgel templated capsules
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Single-step formation of degradable intracellular biomolecule microreactors
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Designing polymeric particles for antigen delivery
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Designing oral vaccines targeting intestinal dendritic cells
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Evaluation of beta-glucan particles as mucosal delivery systems in the Peyer's patch regions of the murine small intestine
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Mucosal irritation potential of polyelectrolyte multilayer capsules
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Evaluation of β-glucan particles as mucosal delivery system in the Peyer's patch regions of the murine small intestine
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Use of endospore-forming bacteria as an active oxygen scavenger in plastic packaging materials
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Layer-by-layer incorporation of growth factors in decellularized aortic heart valve leaflets
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Designing hyaluronic acid-based layer-by-layer capsules as a carrier for intracellular drug delivery
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Polymeric microcapsules with light responsive properties for encapsulation and release
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Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery
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Self-exploding capsules
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Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death
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- Journal Article
- A1
- open access
A single step process for the synthesis of antigen laden thermosensitive microparticles
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Facile two-step synthesis of porous antigen-loaded degradable polyelectrolyte microspheres
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Polymeric multilayer capsules in drug delivery
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Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens
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On-demand click functionalization of polyurethane films and foams
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'Giant' Hollow Multilayer Capsules by Microfluidic Templating
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The pros and cons of polyelectrolyte capsules in drug delivery
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Pulsed in vitro release and in vivo behavior of exploding microcapsules
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'Clicked' polymeric microcapsules and beads: Azide-alkyne versus thiol-ene and thiol-yne approach (Abstract of Lecture)
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Polyelectrolyte microcapsules for biomedical applications
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Direction specific release from giant microgel-templated polyelectrolyte microcontainers
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Intracellular processing of proteins mediated by biodegradable polyelectrolyte capsules
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Thiol-ene and thil-yne 'click' chemistry for preparation of functional beads (Abstract of Lecture)
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Exploration of novel functionalization concepts for surfaces, beads and microcapsules
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Nanorods as wavelength-selective absorption centers in the visible and near-infrared regions of the electromagnetic spectrum
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Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters)
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Biodegradable microgels by click chemistry
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Degradable microgels and hollow capsules by 'click' chemistry
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Prolonged gene silencing in hepatoma cells and primary hepatocytes after siRNA delivery with biodegradable poly(beta-amino esters)
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Biodegradable microcapsules designed via "click" chemistry
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Self exploding microcapsules
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Biodegradable microcapsules designed via 'click' chemistry
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Degradable multilayer films and hollow capsules via a 'Click' strategy
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Self-Exploding Beads Releasing Microcarriers
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Microcapsules Ejecting Nanosized Species into the Environment
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Process design applied to optimise a directly compressible powder produced via a continuous manufacturing process
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Stimuli-responsive polyelectrolyte microcapsules for biomedical applications
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Evaluation of encoded layer-by-layer coated microparticles as protease sensors
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Layer-by-layer coated digitally encoded microcarriers for quantification of proteins in serum and plasma
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Biodegradable microgels by click chemistry
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Stimuli-responsive multilayered hybrid nanoparticle/polyelectrolyte capsules
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Ultrasound-triggered release from multilayered capsules
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Nucleic acid delivery: Where material sciences and bio-sciences meet
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Ultrasound stimulated release and catalysis using polyelectrolyte multilayer capsules
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Release mechanisms for polyelectrolyte capsules
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Self-rupturing and hollow microcapsules prepared from bio-polyelectrolyte-coated microgels
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In vivo cellular uptake, degradation, and biocompatibility of polyelectrolyte microcapsules
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Multifunctional layer-by-layer coating of digitally encoded microparticles
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- Journal Article
- A1
- open access
Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA
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Pulsed drug delivery
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Layer-by-layer coating of degradable microgels for pulsed drug delivery
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Intracellularly degradable polyelectrolyte microcapsules
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Self-exploding lipid-coated microgels
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Glucose-responsive polyelectrolyte capsules
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- PhD Thesis
- open access
Polyelectrolyte microcapsules for pharmaceutical applications
(2006) -
Synthesis of monodisperse biodegradable microgels in microfluidic devices
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Self-rupturing microcapsules
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Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching