Ghent University Academic Bibliography

Journal Article
A1
open access

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Bram Bogaert (UGent) , Felix Sauvage, Roberta Guagliardo, Cristina Muntean (UGent) , [missing] Van Phuc Nguyen, Eline Pottie (UGent) , Mike Wels (UGent) , An-Katrien Minnaert (UGent) , Riet De Rycke (UGent) , Qiangbing Yang, et al.

(2022) JOURNAL OF CONTROLLED RELEASE. 350. p.256-270

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Journal Article
A1
open access

Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Anne Huppertsberg, Leonard Kaps, Zifu Zhong (UGent) , Sascha Schmitt, Judith Stickdorn, Kim Deswarte (UGent) , Francis Combes (UGent) , Christian Czysch, Jana De Vrieze, Sabah Kasmi (UGent) , et al.

(2021) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 143(26). p.9872-9883

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Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte (UGent) , Kaloian Koynov, Bianka Golba (UGent) , Tingting Ye (UGent) , Zifu Zhong (UGent) , Sabah Kasmi (UGent) , Alexander Lamoot (UGent) , Yong Chen (UGent) , et al.

(2021) ACS APPLIED MATERIALS & INTERFACES. 13(5). p.6011-6022

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Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn (UGent) , Simon Van Herck (UGent) , Lutz Nuhn, Kim Deswarte (UGent) , Zifu Zhong (UGent) , et al.

(2021) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 60(17). p.9467-9473

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Journal Article
A1
open access

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

An-Katrien Minnaert (UGent) , Helena Vanluchene (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Stefaan De Smedt (UGent) , Koen Raemdonck (UGent) , Niek Sanders (UGent) and Katrien Remaut (UGent)

(2021) ADVANCED DRUG DELIVERY REVIEWS. 176.

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Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles

Bi Wang, Simon Van Herck (UGent) , Yong Chen (UGent) , Xiangyang Bai, Zifu Zhong (UGent) , Kim Deswarte (UGent) , Bart Lambrecht (UGent) , Niek Sanders (UGent) , Stefan Lienenklaus, Hans W. Scheeren, et al.

(2020) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 142(28). p.12133-12139

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Journal Article
A1
open access

The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Lien Van Hoecke (UGent) , Kenny Roose (UGent) , Marlies Ballegeer (UGent) , Zifu Zhong (UGent) , Niek Sanders (UGent) , Stefaan De Koker (UGent) , Xavier Saelens (UGent) and Sandra Van Lint (UGent)

(2020) MOLECULAR THERAPY-NUCLEIC ACIDS. 22. p.373-381

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Journal Article
A1
open access

Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy

Hui Li, Simon Van Herck (UGent) , Yongjun Liu, Yanyun Hao, Xiaochu Ding, Lutz Nuhn, Zifu Zhong (UGent) , Francis Combes (UGent) , Niek Sanders (UGent) , Stefan Lienenklaus, et al.

(2020) ACS BIOMATERIALS SCIENCE & ENGINEERING. 6(9). p.4993-5000

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Miscellaneous
open access

Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine

Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn (UGent) , Simon Van Herck (UGent) , Lutz Nuhn (UGent) , Kim Deswarte (UGent) , Zifu Zhong (UGent) , et al.

(2020) bioRxiv.

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Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

Jana De Vrieze, Benoit Louage (UGent) , Kim Deswarte (UGent) , Zifu Zhong (UGent) , Ruben De Coen (UGent) , Simon Van Herck (UGent) , Lutz Nuhn, Camilla Kaas Frich, Alexander N Zelikin, Stefan Lienenklaus, et al.

(2019) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 58(43). p.15390-15395

Academic Bibliography

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Lipid-polyglutamate nanoparticle vaccine platform

Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles

The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy

Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

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