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STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity
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CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage
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The Z-nucleic acid sensor ZBP1 in health and disease
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Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
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Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
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Autoantibodies against type I IFNs in patients with critical influenza pneumonia
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Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
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Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria
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TGF-beta regulates the stem-like state of PD-1(+) TCF-1(+) virus-specific CD8 T cells during chronic infection
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TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
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Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A
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SARS-CoV-2–related MIS-C : a key to the viral and genetic causes of Kawasaki disease?
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ILC3s control splenic cDC homeostasis via lymphotoxin signaling
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Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice
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The human fetal thymus generates invariant effector γδ T cells
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Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
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Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
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Imaging resident and recruited macrophage contribution to Wallerian degeneration
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The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF
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Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
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Transcriptional and functional profiling defines human small intestinal macrophage subsets
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GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever
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PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
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Macrophages of distinct origins contribute to tumor development in the lung
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- Miscellaneous
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FcRn is mother's milk to allergen tolerance
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A new lead to NLRP3 inhibition
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Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
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Mycolactone subverts immunity by selectively blocking the Sec61 translocon
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The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
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Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection
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NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNF AIP3/A20
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NLRP2 controls age-associated maternal fertility
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Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
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Transcriptional repressor ZEB2 promotes terminal differentiation of CD8⁺ effector and memory T cell populations during infection
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Immunity induced by a broad class of inorganic crystalline materials is directly controlled by their chemistry
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Monocytes find a new place to dwell in the niche of heartbreak hotel
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Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
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Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength
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Notch pathway activation targets AML-initiating cell homeostasis and differentiation
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Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
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Macrophages induce differentiation of plasma cells through CXCL10/IP-10
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Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells
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Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
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ETV6 mutations in early immature human T cell leukemias
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Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
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Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
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Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
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Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation
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Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice