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Use of 3-hydroxy-4-(trifluoromethyl)azetidin-2-ones as building blocks for the preparation of trifluoromethyl-containing aminopropanes, 1,3-oxazinan-2-ones, aziridines, and 1,4-dioxan-2-ones
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Formation of fluorinated amido esters through unexpected C3-C4 bond fission in 4-trifluoromethyl-3-oxo-β-lactams
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- Journal Article
- A1
- open access
Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones
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Cobalt carbonyl-catalyzed carbonylation of functionalized aziridines to versatile β-lactam building blocks
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Use of α,ω-dichloroketimine building blocks for the construction of 1-azabicyclo[3.1.0]hexanes, piperidines, pyridines, pyrroles and tetrahydroindoles
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- Journal Article
- A1
- open access
Carbonylation of aziridines as a powerful tool for the synthesis of functionalized β-lactams
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- Journal Article
- A1
- open access
Reactivity of 3-oxo-β-lactams with respect to primary amines : an experimental and computational approach
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Synthesis of trifluoromethylated azetidines, aminopropanes, 1,3-oxazinanes, and 1,3-oxazinan-2-ones starting from 4-trifluoromethyl-β-lactam building blocks
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- Journal Article
- A1
- open access
Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl)azetidin-2-ones and their transformation into 3,4-oxolane-fused bicyclic β-lactams
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- Journal Article
- A1
- open access
Deployment of small-ring azaheterocycles as building blocks for the synthesis of organofluorine compounds
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Synthesis and applications of 3-methylene-4-(trifluoromethyl)azetidin-2-ones as building blocks for the preparation of mono- and spirocyclic 4-CF3-β-lactams
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- Journal Article
- A1
- open access
Synthesis and antimicrobial/cytotoxic assessment of ferrocenyl oxazinanes, oxazinan-2-ones, and tetrahydropyrimidin-2-ones
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- Journal Article
- A1
- open access
Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines
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Selective synthesis of cis- and trans-2-(methyl/phenyl)-3-(trifluoromethyl)aziridines and their regio- and stereospecific ring opening
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Synthesis of novel thymine-β-lactam hybrids and evaluation of their anti-tumor activity
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Synthesis of 2-hydroxy-1,4-oxazin-3-ones through ring transformation of 3-hydroxy-4-(1,2-dihydroxyethyl)-β-lactams and a study of their reactivity
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Nucleophile-directed selective transformation of cis-1-tosyl-2-toxyloxymethyl-3-(trifluoromethyl)aziridine into aziridines, azetidines, and benzo-fused dithianes, oxathianes, dioxanes, and (thio)morpholines
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Regioselectivity in the ring opening of non-activated aziridines
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Chemical and enzymatic synthesis of 2-(2-carbamoylethyl)- and 2-(2-carboxyethyl)aziridines and their conversion into δ-lactams and γ-lactones
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- Journal Article
- A1
- open access
N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis
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- Journal Article
- A1
- open access
Synthesis and reactivity of spiro-fused β-lactams
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Transformation of trans-4-aryl-3-chloro-1-(2-chloroethyl)azetidin-2-ones into 3-aryl-2-(ethylamino)propan-1-ols via intermediate 1-(1-aryl-2-chloro-3-hydroxypropyl)aziridines and trans-2-aryl-3-(hydroxymethyl)aziridines
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- Journal Article
- A1
- open access
Straightforward synthesis of 1-alkyl-2-(trifluoromethyl)aziridines starting from 1,1,1-trifluoroacetone
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Synthesis of 3,4-fused bicyclic β-lactams and their transformation into methyl cis-3-aminotetrahydrofuran-2-carboxylates
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- Journal Article
- A1
- open access
Rhodium-catalysed hydroformylation of N-(2-propenyl)-β-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)but-1-enyl]acetamides
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- Journal Article
- A1
- open access
Use of functionalized β-lactams as building blocks in heterocyclic chemistry
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- Journal Article
- A1
- open access
Microwave-assisted regioselective ring opening of non-activated aziridines by lithium aluminium hydride
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- Journal Article
- A1
- open access
Conjugate addition of 2-(bromomethyl)- and 2-(2-bromoethyl)piperidine to alkyl acrylates : application towards the synthesis of 2-(methoxycarbonyl)indolizidine
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- Journal Article
- A1
- open access
Synthesis of 2-[(arylmethylene)amino]cyclopropanecarbonitriles via a two-step ring transformation of 2-(cyanomethyl)aziridines
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Diastereoselective Synthesis of Bicyclic gamma-Lactams via Ring Expansion of Monocydic beta-Lactams
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Synthesis of novel 2-alkoxy-3-amino-3-arylpropan-1-ols and 5-alkoxy-4-aryl-1,3-oxazinanes with antimalarial activity