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Pharmacokinetics of gamma‐hydroxybutyric acid in 6‐week‐old swine (Sus scrofa domesticus) after intravenous and oral administration
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- Journal Article
- A1
- open access
General purpose models for intravenous anesthetics, the next generation for target-controlled infusion and total intravenous anesthesia?
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- Journal Article
- A1
- open access
Novel antimicrobial agents for gram-negative pathogens
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- Journal Article
- A1
- open access
Evidence-based dosing of convalescent plasma for COVID-19 in future trials
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Dexmedetomidine clearance decreases with increasing drug exposure : implications for current dosing regimens and target-controlled infusion models assuming linear pharmacokinetics
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- Journal Article
- A1
- open access
Non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients with atrial fibrillation and (morbid) obesity or low body weight : a systematic review and meta-analysis
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- Journal Article
- A1
- open access
What's new in intravenous anaesthesia? New hypnotics, new models and new applications
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- Journal Article
- A1
- open access
Why we may need higher doses of beta-lactam antibiotics : introducing the 'maximum tolerable dose'
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- Journal Article
- A1
- open access
Antibiotic cycling affects resistance evolution independently of collateral sensitivity
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Clinical validation of pharmacokinetic/pharmacodynamic models for propofol infusion : response to Br J Anaesth 2021 : 126 : e172-4
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Resisting neural inertia : an exercise in floccinaucinihilipilification?
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- Journal Article
- A1
- open access
Prospective clinical validation of the Eleveld propofol pharmacokinetic-pharmacodynamic model in general anaesthesia
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- Journal Article
- A1
- open access
Enrofloxacin dose optimization for the treatment of colibacillosis in broiler chickens using a drinking behaviour pharmacokinetic model
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The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients : data from the Multinational Sampling Antibiotics in Renal Replacement Therapy study
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- Journal Article
- A1
- open access
Nebulized colistin in ventilator-associated pneumonia and tracheobronchitis : historical background, pharmacokinetics and perspectives
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Population pharmacokinetics of lisinopril in hypertensive children with mild to moderate renal impairment
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- Journal Article
- A1
- open access
Outpatient parenteral antifungal therapy (OPAT) for invasive fungal infections with intermittent dosing of liposomal amphotericin B
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Antimicrobial therapeutic drug monitoring in critically ill adult patients : a Position Paper#
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Target-controlled-infusion models for remifentanil dosing consistent with approved recommendations
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Moderate-to-deep sedation using target-controlled infusions of propofol and remifentanil : adverse events and risk factors : a retrospective cohort study of 2937 procedures
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PKPD modeling and dosing considerations in advanced ovarian cancer patients treated with cisplatin-based intraoperative intraperitoneal chemotherapy
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Intranasal dexmedetomidine in elderly subjects with or without beta blockade : a randomised double-blind single-ascending-dose cohort study.
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Target-controlled infusion of cefepime in critically Ill patients
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Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem : a comparison of eight pharmacokinetic models
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- Journal Article
- A1
- open access
Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia
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- Journal Article
- A1
- open access
Phenobarbital, midazolam pharmacokinetics, effectiveness, and drug-drug interaction in asphyxiated neonates undergoing therapeutic hypothermia
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How to score sedation and adjust the administration rate of sedatives in horses : a literature review and introduction of the Ghent Sedation Algorithm
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- Journal Article
- A1
- open access
A comparison of propofol-to-BIS post-operative intensive care sedation by means of target controlled infusion, Bayesian-based and predictive control methods : an observational, open-label pilot study
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Alfaxalone total intravenous anaesthesia in dogs : pharmacokinetics, cardiovascular data and recovery characteristics
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Pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs (Cavia porcellus)
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Population pharmacokinetics and simulations of imipenem in critically ill patients undergoing continuous renal replacement therapy
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Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion
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Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects
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Drug selection for ambulatory procedural sedation
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- Journal Article
- A1
- open access
Target-controlled continuous infusion for antibiotic dosing : proof-of-principle in an in-silico vancomycin trial in intensive care unit patients
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Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients
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A physiologically based pharmacokinetic perspective on the clinical utility of albumin-based dose adjustments in critically ill patients
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PBPK in preterm and term neonates : a review
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A novel scale linking potency and dosage to estimate anticholinergic exposure in older adults : the Muscarinic Acetylcholinergic Receptor ANTagonist Exposure Scale
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Influence of Bayesian optimization on the performance of propofol target-controlled infusion
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Pharmacokinetic interactions between simeprevir and ledipasvir in treatment naive hepatitis C virus genotype 1-Infected patients without cirrhosis treated with a simeprevir-sofosbuvir-ledipasvir regimen
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Dexmedetomidine pharmacokineticpharmacodynamic modelling in healthy volunteers, 1 : influence of arousal on bispectral index and sedation
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Prophylactic atropine administration attenuates the negative haemodynamic effects of induction of anaesthesia with propofol and high-dose remifentanil : a randomised controlled trial
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- Journal Article
- A1
- open access
Comparative population pharmacokinetics and absolute oral bioavailability of COX-2 selective inhibitors celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus)
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The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections
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Acute and life-threatening remifentanil overdose resulting from the misuse of a syringe pump
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Probability to tolerate laryngoscopy and noxious stimulation response index as general indicators of the anaesthetic potency of sevoflurane, propofol, and remifentanil
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Comparisons of electroencephalographically derived measures of hypnosis and antinociception in response to standardized stimuli during target-controlled propofol-remifentanil anesthesia
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The safety of target-controlled infusions
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Rupatadine : global safety evaluation in allergic rhinitis and urticaria