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We need to talk about Kekule : the 150th anniversary of the benzene structure
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WY 1048, a 17-methyl 19-nor D-ring analog of vitamin D3, in combination with risedronate restores bone mass in a mouse model of postmenopausal osteoporosis
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- Journal Article
- A1
- open access
Possibility of [1,5] sigmatropic shifts in bicyclo[4.2.0]octa-2,4-dienes
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- Journal Article
- A1
- open access
1,25-Dihydroxyvitamin D-3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients
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A proteomic approach on the effects of TX527, a 1α,25-dihydroxyvitamin D₃ analog, in human T lymphocytes
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Cell cycle arrest and apoptosis induced by 1α,25(OH)₂D₃ and TX527 in Kaposi sarcoma is VDR dependent
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- Conference Paper
- C3
- open access
Convenient and versatile route to 2-alkyl-19-nor-analogues of calcitriol
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Synthesis of 2-ethyl-19-nor analogs of 1α,25-dihydroxyvitamin D₃
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The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease
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A convenient and versatile route to 2-alkyl-19-nor-analogs of calcitriol
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Applications of (4+3) cycloaddition reactions of furfuryl cations
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Analogs of calcitriol
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CD-ring modified vitamin D-3 analogs and their superagonistic action
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Cyclopentanones XIV : the synthesis of a prostanoid synthon starting from 3-alkyl-1,2,4-cyclopentanetriones
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Cyclopentanones XVII : prostaglandin synthesis involving the lithium-liquid ammonia reduction of 3-alkyl-4-hydroxy-2-(1′-octynyl)-2-cyclopentenones
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Development of Analogues of 1 alpha,25-Dihydroxyvitamin D-3 with Biased Side-Chain Orientation: C20 Methylated Des-C,D-homo Analogues
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- Journal Article
- A1
- open access
Synthesis of 1 alpha,25-Dihydroxyvitamin D Analogues Featuring a S-2-symmetric CD-ring Core
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Synthesis of 22-oxaspiro[4.5]decane CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D3
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Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D-3 or a 17-methyl-D-ring analog
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Antiproliferative and Calcemic Actions of Trans-Decalin CD-Ring Analogs of 1,25-Dihydroxyvitamin D-3
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Nonenzymic polycyclisation of analogues of oxidosqualene with a preformed C-ring
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Synthesis of a tripodal scaffold for solid phase synthesis of artificial receptors
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Superagonistic Fluorinated Vitamin D3 analogs Stabilize Helix 12 of the Vitamin D receptor
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Microarray analysis of MCF-7 breast cancer cells treated with 1,25-(OH)(2)D-3 or the analog WY1112
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Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione
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Mechanism and potential of the growth-inhibitory actions of vitamin D and analogs
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The development of CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D
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Fast and easy detection of aromatic amines on solid support
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Asymmetric synthesis of the epimeric (3S)-3-((E)-Hex-1-eny1)-2-methylcyclohexanones
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- Journal Article
- A1
- open access
Removal of C-ring from the CD-ring skeleton of 1 alpha,25-dihydroxyvitamin D-3 does not alter its target tissue metabolism significantly
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Solid-supported synthesis of highly functionalized tripodal peptides with flexible but preorganized geometry: towards potential serine protease mimics
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Application of the B-alkyl Suzuki-Miyaura cross-coupling reaction to the stereoselective synthesis of analogues of (3S)-oxidosqualene
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Vitamin D analogs and coactivators
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Application of the solid-phase Julia-Lythgoe olefination in vitamin D side-chain construction
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Asymmetric synthesis of (7aS)-7a-methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and useful derivatives thereof
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Synthesis of spiro[4.5] decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D-3
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Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction
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Fine-tuning furan toxicity: fast and quantitative DNA interchain crosslink formation upon selective oxidation of a furan containing oligonucleotide
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Synthesis of 2-methyl and ethyl-substituted 19-nor-1 alpha,25-dihydroxyvitamin D-3 analogues via the cyclovitamin strategy
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Mechanisms for the selective action of Vitamin D analogs
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Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs
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1,25-Dihydroxyvitamin D-3 and analogues protect primary human keratinocytes against UVB-induced DNA damage
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Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs
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Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : cis-perhydrindane CE-ring analogues
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Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : spiro[5.5]undecane CF-ring analogues
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Two 14-epi analogues of 1,25-dihydroxyvitamin D-3 protect human keratinocytes against the effects of UVB
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Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs
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- Journal Article
- A1
- open access
Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity
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- Journal Article
- A1
- open access
Synthesis and binding affinity studies of muscarinic receptor antagonists related to dehydrohimbacine
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Carbon-carbon bond formation on solid support : application of the classical Julia-Lythgoe olefination