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Sterile triggers drive joint inflammation in TNF‐ and IL-1β‐dependent mouse arthritis models
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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function
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OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
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Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice
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Innovative mouse models for the tumor suppressor activity of protocadherin-10 isoforms
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Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
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Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
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A20 controls RANK-dependent osteoclast formation and bone physiology
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Myb drives B-cell neoplasms and myeloid malignancies in vivo
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Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding
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OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
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Fibrotic enzymes modulate wound-induced skin tumorigenesis
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Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity
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Response to correspondence on 'Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles : a multi-center evaluation'
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Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice
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A new transgenic mouse line for imaging mitochondrial calcium signals
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MALT1 targeting suppresses CARD14‐induced psoriatic dermatitis in mice
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Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium
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Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
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Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
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Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles : a multi-center evaluation
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MALT1 proteolytic activity suppresses autoimmunity in a T cell intrinsic manner
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A new mouse model to study the role of ectopic Nanos3 expression in cancer
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Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells
(2018) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 115(14). p.3680-3685 -
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A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
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DMRT5 together with DMRT3 directly controls hippocampus development and neocortical area map formation
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Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4
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Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange
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Elevated ΔNp63α levels facilitate epidermal and biliary oncogenic transformation
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NOD-like receptor Nlrp2 is dispensable for immune signaling, but critical for efficient early embryonic development in aged oocytes
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Characterization of new transgenic mouse models for two Charcot-Marie-tooth-causing HspB1 mutations using the Rosa26 locus
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Fast generation of conditional ROSA26-based mouse models that recapitulate genomic events in human T-ALL
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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(50). p.14384-14389 -
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Overexpression of glucocorticoid-induced leucine zipper (GILZ) increases susceptibility to imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1
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p120 Catenin-mediated stabilization of E-cadherin is essential for primitive endoderm specification
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NLRP2 controls age-associated maternal fertility
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An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model
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Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
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Heme-deficient NO-unresponsive sGC knock-in mice: novel aspects of NO sGC signaling in cardiovascular (patho)physiology
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RNF4 is required for DNA double-strand break repair in vivo
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The ROSA26-iPSC mouse : a conditional, inducible, and exchangeable resource for studying cellular (de)differentiation
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Mice overexpressing β-1,4-galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis
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Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells
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Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice
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Caspase-14 protects against epidermal UVB photo-damage and water loss.
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Caspase-14 protects against epidermal UVB photodamage and water loss
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Caspase-14 protects against epidermal UVB photo-damage and water loss
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The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production
(2006) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 103(7). p.2292-2297 -
Role of caspase-14 in terminal differentiation of keratinocytes
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Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders