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A generic reverse osmosis model for full-scale operation
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- Conference Paper
- C3
- open access
Validation of a generic steady state model for full-scale Reverse Osmosis
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- Conference Paper
- C1
- open access
Validation of a generic steady state model for full-scale reverse osmosis
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The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses
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Dynamic validation of online applied and surrogate-based models for tertiary ozonation on pilot-scale
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Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation
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Potential of near-infrared chemical imaging as process analytical technology tool for continuous freeze-drying
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Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying
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Model calibration and validation of a full-scale reverse osmosis process
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Towards advanced aeration modelling : from blower to bubbles to bulk
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Surrogate-based correlation models in view of real-time control of ozonation of secondary treated municipal wastewater-model development and dynamic validation
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- Conference Paper
- C3
- open access
Extension of a mechanistic model for drying of single pharmaceutical granules to semi-continuous fluid bed drying
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- Journal Article
- A1
- open access
Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze-drying
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In-depth experimental analysis of pharmaceutical twin-screw wet granulation in view of detailed process understanding
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- Journal Article
- A1
- open access
Modelling the primary drying step for the determination of the optimal dynamic heating pad temperature in a continuous pharmaceutical freeze-drying process for unit doses
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- Journal Article
- A1
- open access
Mechanistic modelling of infrared mediated energy transfer during the primary drying step of a continuous freeze-drying process
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Modelling and sensitivity analysis of urinary platinum excretion in anticancer chemotherapy for the recovery of platinum
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A dynamic design space for primary drying during batch freeze-drying
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Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
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The use of rheology combined with differential scanning calorimetry to elucidate the granulation mechanism of an immiscible formulation during continuous twin-screw melt granulation
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The use of rheology to elucidate the granulation mechanisms of a miscible and immiscible system during continuous twin-screw melt granulation
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- Conference Paper
- C3
- open access
Model-based process analysis in continuous manufacturing of pharmaceuticals : calibration of a fluid bed dryer model
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Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying
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Towards advanced aeration modelling: from blower to bubbles to bulk
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- Conference Paper
- C3
- open access
Model-based optimization of the primary drying step during freeze-drying
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Gaining process knowledge by using mechanistic models for fluidized bed drying in a continuous manufacturing environment
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Towards improved accuracy in modelling aeration efficiency by accounting for bubble size distribution dynamics
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Model-based optimization of the primary drying step during freeze-drying
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Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process
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Global sensitivity analysis applied to drying models for one or a population of granules
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Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass-energy balances
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Process monitoring and modeling of a continuous pharmaceutical from powder to tablet process line using a mass and energy balance
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Monitoring and modelling of a continuous from-powder-to-tablet process line
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Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
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- Conference Paper
- C3
- open access
Two-dimensional PBM for simultaneous modelling of drying and breakage of pharmaceutical granules
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Applying reconstruction methods on the solution of a moment-based pharmaceutical drying process Population Balance Model
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A two-dimensional PBM for continuous drying of a population of granules including drying and breakage
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- Conference Paper
- C3
- open access
Mechanistic modelling for process understanding of fluidized bed drying process part of a full continuous pharmaceutical manufacturing line
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Reduction of a single granule drying model: an essential step in preparation of a population balance model with a continuous growth term
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Development of a population balance model of a pharmaceutical drying process and testing of solution methods
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A GLUE uncertainty analysis of a drying model of pharmaceutical granules
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- Conference Paper
- C1
- open access
Global sensitivity analysis on a PBM-model describing the drying behaviour of wet pharmaceutical granules
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- Conference Paper
- C1
- open access
Scenario analysis on a PBM describing the drying behaviour of wet pharmaceutical granules
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The use of mass and energy balances for process monitoring of a full continuous pharmaceutical from powder to tablet manufacturing
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- Conference Paper
- C3
- open access
Using a PBM to describe the drying behaviour of wet pharmaceutical granules : scenario analysis and GSA
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- Conference Paper
- C3
- open access
Process monitoring of a full continuous pharmaceutical tabletting line : mass and energy balance analysis
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- Conference Paper
- C3
- open access
Process monitoring for the continuous tabletting line ConsiGma using in-line measurements
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Mechanistic modelling of the drying behaviour of single pharmaceutical granules
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- Conference Paper
- C3
- open access
Application of model uncertainty analysis on the modelling of the drying behaviour of single pharmaceutical granules
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- Conference Paper
- C3
- open access
Application of model uncertainty analysis on the modelling of the drying behaviour of single pharmaceutical granules