Ghent University Academic Bibliography

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Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences.

K Declerck, Claudina Perez Novo (UGent) , L Grielens, G Van Camp, A Suter and W Vanden Berghe

(2021) BMC COMPLEMENTARY MEDICINE AND THERAPIES. 21(1).
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Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette Roels (UGent) , Morgan Thénoz (UGent) , B Szarzyńska, M Landfors, Stien De Coninck (UGent) , Lisa Demoen (UGent) , Lien Provez (UGent) , Anna Kuchmiy (UGent) , Steven Strubbe (UGent) , Lindy Reunes (UGent) , et al.

(2020) BLOOD CANCER DISCOVERY. 1(3). p.274-289
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- Conference Paper
- C3
Introduction of a heart failure nurse for the support of in-hospital management of mainly elderly patients with acute HF results in a better outcome after 1 year follow-up

Johan De Sutter (UGent) , B Vande Kerckhove, Sofie Pardaens (UGent) , AM Willems, C Weytjens, G Van Camp and Dirk De Bacquer (UGent)

(2013) EUROPEAN HEART JOURNAL. 34(suppl. 1). p.327-327
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Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2

I Schrauwen, Koen Venken (UGent) , K Vanderstraeten, M Thys, JJ Hendrickx, E Fransen, Lut Van Laer (UGent) , PJ Govaerts, M Verstreken, I Schatteman, et al.

(2010) GENES AND IMMUNITY. 11(3). p.246-253
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- Journal Article
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Genetic Studies on Noise-Induced Hearing Loss: A Review

A Konings, Lut Van Laer (UGent) and G Van Camp

(2009) EAR AND HEARING. 30(2). p.151-159
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Characterization of the murine Dfna5 promoter and regulatory regions

K Vrijens, G Van Camp and Lut Van Laer (UGent)

(2009) GENE. 432(1-2). p.82-90
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Influence of exogenic factors on age-related hearing impairment

M Baur, E Fransen, A Tropitzsch, Lut Van Laer (UGent) , PS Mauz, G Van Camp, N Blin and M Pfister

(2009) HNO. 57(10). p.1023-1028
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Audiometric shape and presbycusis

K Demeester, A van Wieringen, JJ Hendrickx, V Topsakal, E Fransen, Lut Van Laer (UGent) , G Van Camp and P Van de Heyning

(2009) INTERNATIONAL JOURNAL OF AUDIOLOGY. 48(4). p.222-232
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Analysis of Gene Polymorphisms Associated with K+ Ion Circulation in the Inner Ear of Patients Susceptible and Resistant to Noise-induced Hearing Loss

M Pawelczyk, Lut Van Laer (UGent) , E Fransen, E Rajkowska, A Konings, PI Carlsson, E Borg, G Van Camp and M Sliwinska-Kowalska

(2009) ANNALS OF HUMAN GENETICS. 73. p.411-421
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Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations

A Konings, Lut Van Laer (UGent) , S Michel, M Pawelczyk, PI Carlsson, ML Bondeson, E Rajkowska, A Dudarewicz, A Vandevelde, E Fransen, et al.

(2009) EUROPEAN JOURNAL OF HUMAN GENETICS. 17(3). p.329-335
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Candidate Gene Association Study for Noise-induced Hearing Loss in Two Independent Noise-exposed Populations

A Konings, Lut Van Laer (UGent) , A Wiktorek-Smagur, E Rajkowska, M Pawelczyk, PI Carlsson, ML Bondeson, A Dudarewicz, A Vandevelde, E Fransen, et al.

(2009) ANNALS OF HUMAN GENETICS. 73. p.215-224
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- Journal Article
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GRM7 variants confer susceptibility to age-related hearing impairment

RA Friedman, Lut Van Laer (UGent) , MJ Huentelman, SS Sheth, E Van Eyken, JJ Corneveaux, WD Tembe, RF Halperin, AQ Thorburn, S Thys, et al.

(2009) HUMAN MOLECULAR GENETICS. 18(4). p.785-796
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Phenotypic variability of patients homozygous for the GJB2 mutation 35delG cannot be explained by the influence of one major modifier gene

Nele Hilgert, Matthew Huentelman, AQ Thorburn, Erik Fransen, Nele Dieltjens, M Meuller-Malesinska, A Pollak, A Skorka, J Waligora, R Ploski, et al.

(2009) EUROPEAN JOURNAL OF HUMAN GENETICS. 17(4). p.517-524
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- Journal Article
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Human hereditary hearing impairment: mouse models can help to solve the puzzle

K Vrijens, Lut Van Laer (UGent) and G Van Camp

(2008) HUMAN GENETICS. 124(4). p.325-348
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Strong Linkage Disequilibrium for the Frequent GJB2 35delG Mutation in the Greek Population

H Kokotas, Lut Van Laer (UGent) , M Grigoriadou, V Iliadou, J Economides, S Pomoni, A Pampanos, N Eleftheriades, E Ferekidou, S Korres, et al.

(2008) AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 146A(22). p.2879-2884
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- Journal Article
- A1
Genome-wide SNP-based linkage scan identifies a locus on 8q24 for an age-related hearing impairment trait

JR Huyghe, Lut Van Laer (UGent) , JJ Hendrickx, E Fransen, K Demeester, V Topsakal, S Kunst, M Manninen, M Jensen, A Bonaconsa, et al.

(2008) AMERICAN JOURNAL OF HUMAN GENETICS. 83(3). p.401-407
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- A1
- open access
The grainyhead like 2 gene (GRHL2), alias TFCP2L3, is associated with age-related hearing impairment

Lut Van Laer (UGent) , E VAN EYKEN, E FRANSEN, Jeroen HUYGHE, V TOPSAKAL, JJ HENDRICKX, S HANNULA, E MAKI-TORKKO, M JENSEN, K DEMEESTER, et al.

(2008) HUMAN MOLECULAR GENETICS. 17(2). p.159-169
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The complexity of age-related hearing impairment: Contributing environmental and genetic factors

E Van Eyken, G Van Camp and Lut Van Laer (UGent)

(2007) AUDIOLOGY AND NEURO-OTOLOGY. 12(6). p.345-358
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New, easy and rapid high-throughput detection method for the common GJB2 (CX26), 35delG mutation

E Van Eyken, G Van Camp, JJ Hendrickx, K Demeester, A Vandevelde, J Ben Azza, PV De Heyning and Lut Van Laer (UGent)

(2007) GENETIC TESTING. 11(3). p.231-234
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- Journal Article
- A1
Prevalence of tinnitus and audiometric shape

K Demeester, A van Wieringen, JJ Hendrickx, V Topsakal, E Fransen, Lut Van Laer (UGent) , D De Ridder, G Van Camp and P Van de Heyning

(2007) B-ENT. p.37-49
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A novel DFNA5 mutation does not cause hearing loss in an Iranian family

Lut Van Laer (UGent) , NC Meyer, M Malekpour, Y Riazalhosseini, M Moghannibashi, K Kahrizi, A Vandevelde, F Alasti, H Najmabadi, G Van Camp, et al.

(2007) JOURNAL OF HUMAN GENETICS. 52(6). p.549-552
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Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations

A Konings, Lut Van Laer (UGent) , M Pawelczyk, PI Carlsson, ML Bondeson, E Rajkowska, A Dudarewicz, A Vandevelde, E Fransen, J Huyghe, et al.

(2007) HUMAN MOLECULAR GENETICS. 16(15). p.1872-1883
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The coding polymorphism T263I in TGF-beta 1 is associated with otosclerosis in two independent populations

M THYS, I SCHRAUWEN, K VANDERSTRAETEN, K JANSSENS, N DIELTJENS, K VAN DEN BOGAERT, E FRANSEN, W CHEN, M EALY, M CLAUSTRES, et al.

(2007) HUMAN MOLECULAR GENETICS. 16(17). p.2021-2030
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Contribution of the N-acetyltransferase 2 polymorphism NAT2*6A to age-related hearing impairment

E VAN EYKEN, G VAN CAMP, E FRANSEN, V TOPSAKAL, JJ HENDRICKX, K DEMEESTER, PV DE HEYNING, EM KI-TORKKO, S HANNULA, M SORRI, et al.

(2007) JOURNAL OF MEDICAL GENETICS. 44(9).
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The contribution of GJB2 (Connexin 26) 35delG to age-related hearing impairment and noise-induced hearing loss

E VAN EYKEN, Lut Van Laer (UGent) , E FRANSEN, V TOPSAKAL, JJ HENDRICKX, K DEMEESTER, P VAN DE HEYNING, E MAKI-TORKKO, S HANNULA, M SORRI, et al.

(2007) OTOLOGY & NEUROTOLOGY. 28(7). p.970-975
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KCNQ4: A gene for age-related hearing impairment?

E Van Eyken, Lut Van Laer (UGent) , E Fransen, V Topsakal, N Lemkens, W Laureys, N Nelissen, A Vandevelde, T Wienker, P Van De Heyning, et al.

(2006) HUMAN MUTATION. 27(10). p.1007-1016
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The contribution of genes involved in potassium-recyclingin the inner ear to noise-induced hearing loss

Lut Van Laer (UGent) , PI Carlsson, N Ottschytsch, ML Bondeson, A Konings, A Vandevelde, N Dieltjens, E Fransen, D Snyders, E Borg, et al.

(2006) HUMAN MUTATION. 27(8). p.786-795
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- A2
DFNA2/KCNQ4 and its manifestations.

Els De Leenheer (UGent) , RJ ENSINK, HP KUNST, HA MARRES, Z TALEBIZADEH, F DECLAU, SD SMITH, S USAMI, PH VAN DE HEYNING, G VAN CAMP, et al.

(2006) ADVANCES IN OTO-RHINO-LARYNGOLOGY. 61. p.41-46
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Ozzy, a Jag1 vestibular mouse mutant, displays characteristics of Alagille syndrome

K Vrijens, S Thys, MT De Jeu, AA Postnov, M Pfister, L Cox, A Zwijsen, V Van Hoof, M Mueller, NM De Clerck, et al.

(2006) NEUROBIOLOGY OF DISEASE. 24(1). p.28-40
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Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy

S Delmaghani, FJ del Castillo, V Michel, M Leibovici, A Aghaie, U Ron, Lut Van Laer (UGent) , N Ben-Tal, G Van Camp, D Weil, et al.

(2006) NATURE GENETICS. 38(7). p.770-778
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GJB2 (Connexin 26) mutations are not a major cause of hearing loss in the Indonesian population

RL Snoeckx, B Djelantik, Lut Van Laer (UGent) , P Van de Heyning and G Van Camp

(2005) AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 135A(2). p.126-129
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The influence of genetic variation in oxidative stress genes on human noise susceptibility

PI Carlsson, Lut Van Laer (UGent) , E Borg, ML Bondeson, M Thys, E Fransen and G Van Camp

(2005) HEARING RESEARCH. 202(1-2). p.87-96
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Global and regional parameters of dyssynchrony in ischemic and nonischemic cardiomyopathy

Nico Van de Veire, Johan De Sutter (UGent) , G VAN CAMP, Pascal Van Der Voort (UGent) , P LANCELLOTTI, B COSYNS, P UNGER and Thierry Gillebert (UGent)

(2005) AMERICAN JOURNAL OF CARDIOLOGY. 95(3). p.421-423
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- Conference Paper
- C3
Evaluation of intraventricular dyssynchrony in heart failure patients: A direct comparison between pulsed wave and color tissue Doppler imaging

Johan De Sutter (UGent) , Nico Van de Veire, G VAN CAMP, P LANCELLOTTI, P VANDERVOORT, L MUYLDERMANS, T DE BACKER and P UNGER

(2005) JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 45(3).
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Prevalence of mechanical dyssynchrony in patients with heart failure and preserved left ventricular function (a report from the Belgian Multicenter registry on dyssynchrony)

Johan De Sutter (UGent) , Nico Van de Veire, L MUYLDERMANS, T DE BACKER, E HOFFER, M VAERENBERG, B PAELINCK, P DECOODT, L GABRIEL, Thierry Gillebert (UGent) , et al.

(2005) AMERICAN JOURNAL OF CARDIOLOGY. 96(11). p.1543-1548
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Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

Lut Van Laer (UGent) , M Pfister, S Thys, K Vrijens, M Mueller, L Umans, L Serneels, L Van Nassauw, F Kooy, RJH Smith, et al.

(2005) NEUROBIOLOGY OF DISEASE. 19(3). p.386-399
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DFNA5: hearing impairment exon instead of hearing impairment gene?

Lut Van Laer (UGent) , K Vrijens, S Thys, VFI Van Tendeloo, RJH Smith, DR Van Bockstaele, JP Timmermans and G Van Camp

(2004) JOURNAL OF MEDICAL GENETICS. 41(6). p.401-406
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A novel Z-score-based method to analyze candidate genes for Age-Related Hearing Impairment

E Fransen, Lut Van Laer (UGent) , N Lemkens, G Caethoven, K Flothmann, P Govaerts, P Van de Heyning and G Van Camp

(2004) EAR AND HEARING. 25(2). p.133-141
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Nonsyndromic hearing loss

Lut Van Laer (UGent) , K Cryns, RJH Smith and G Van Camp

(2003) EAR AND HEARING. 24(4). p.275-288
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Age-related hearing impairment (ARHI): environmental risk factors and genetic prospects

E Fransen, N Lemkens, Lut Van Laer (UGent) and G Van Camp

(2003) EXPERIMENTAL GERONTOLOGY. 38(4). p.353-359
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A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment

J Gregan, Lut Van Laer (UGent) , LD Lieto, G Van Camp and SE Kearsey

(2003) BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1638(2). p.179-186
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GJB2 deafness gene shows a specific spectrum of mutations in Japan, including a frequent founder mutation

A Ohtsuka, I Yuge, S Kimura, A Namba, S Abe, Lut Van Laer (UGent) , G Van Camp and S Usami

(2003) HUMAN GENETICS. 112(4). p.329-333
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The WFS1 gene, responsible for low frequency sensorineural hearing loss and Wolfram syndrome, is expressed in a variety of inner ear cells

K Cryns, S Thys, Lut Van Laer (UGent) , Y Oka, M Pfister, L Van Nassauw, RJH Smith, JP Timmermans and G Van Camp

(2003) HISTOCHEMISTRY AND CELL BIOLOGY. 119(3). p.247-256
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Longitudinal and cross-sectional phenotype analysis in a new, large dutch DFNA2/KCNQ4 family.

EMR DE LEENHEER, P HUYGEN, Paul Coucke (UGent) , R ADMIRAAL, G VAN CAMP and C CREMERS

(2002) ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 111(3) 267-274 Part 1).
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Further delineation of the DFNA5 phenotype: Results of speech recognition tests

Els De Leenheer (UGent) , DA VAN ZUIJLEN, Lut Van Laer (UGent) , G VAN CAMP, P HUYGEN, EH HUIZING and C CREMERS

(2002) ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 111(7). p.639-641
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Is DFNA5 a susceptibility gene for age-related hearing impairment?

Lut Van Laer (UGent) , AL DeStefano, RH Myers, K Flothmann, S Thys, E Fransen, GA Gates, G Van Camp and CT Baldwin

(2002) EUROPEAN JOURNAL OF HUMAN GENETICS. 10(12). p.883-886
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- A2
DFNA10/EYA4 - the clinical picture.

Els De Leenheer (UGent) , PL HUYGEN, S WAYNE, M VERSTREKEN, F DECLAU, G VAN CAMP, PH VAN DE HEYNING, RJ SMITH and CW CREMERS

(2002) ADVANCES IN OTO-RHINO-LARYNGOLOGY. 61. p.73-78
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A mutational hot spot in the KCNQ4 gene responsible for autosomal dominant hearing impairment.

G VAN CAMP, Paul Coucke (UGent) , J AKITA, E FRANSEN, S ABE, EMR DE LEENHEER, P HUYGEN, C CREMERS and SI USAMI

(2002) HUMAN MUTATION. 20(1). p.15-19
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Genes in the ear: what have we learned over the last years?

Lut Van Laer (UGent) and G Van Camp

(2001) SCANDINAVIAN AUDIOLOGY. 30. p.44-53
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Speech recognition scores related to age and degree of hearing impairment in DFNA2/KCNQ4 and DFNA9/COCH.

S BOM, EMR DE LEENHEER, FX LEMAIRE, MH KEMPERMAN, W VERHAGEN, H MARRES, H KUNST, R ENSINK, AJ BOSMAN, G VAN CAMP, et al.

(2001) ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY. 127(9). p.1045-1048

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences.

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Introduction of a heart failure nurse for the support of in-hospital management of mainly elderly patients with acute HF results in a better outcome after 1 year follow-up

Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2

Genetic Studies on Noise-Induced Hearing Loss: A Review

Characterization of the murine Dfna5 promoter and regulatory regions

Influence of exogenic factors on age-related hearing impairment

Audiometric shape and presbycusis

Analysis of Gene Polymorphisms Associated with K+ Ion Circulation in the Inner Ear of Patients Susceptible and Resistant to Noise-induced Hearing Loss

Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations

Candidate Gene Association Study for Noise-induced Hearing Loss in Two Independent Noise-exposed Populations

GRM7 variants confer susceptibility to age-related hearing impairment

Phenotypic variability of patients homozygous for the GJB2 mutation 35delG cannot be explained by the influence of one major modifier gene

Human hereditary hearing impairment: mouse models can help to solve the puzzle

Strong Linkage Disequilibrium for the Frequent GJB2 35delG Mutation in the Greek Population

Genome-wide SNP-based linkage scan identifies a locus on 8q24 for an age-related hearing impairment trait

The grainyhead like 2 gene (GRHL2), alias TFCP2L3, is associated with age-related hearing impairment

The complexity of age-related hearing impairment: Contributing environmental and genetic factors

New, easy and rapid high-throughput detection method for the common GJB2 (CX26), 35delG mutation

Prevalence of tinnitus and audiometric shape

A novel DFNA5 mutation does not cause hearing loss in an Iranian family

Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations

The coding polymorphism T263I in TGF-beta 1 is associated with otosclerosis in two independent populations

Contribution of the N-acetyltransferase 2 polymorphism NAT2*6A to age-related hearing impairment

The contribution of GJB2 (Connexin 26) 35delG to age-related hearing impairment and noise-induced hearing loss

KCNQ4: A gene for age-related hearing impairment?

The contribution of genes involved in potassium-recyclingin the inner ear to noise-induced hearing loss

DFNA2/KCNQ4 and its manifestations.

Ozzy, a Jag1 vestibular mouse mutant, displays characteristics of Alagille syndrome

Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy

GJB2 (Connexin 26) mutations are not a major cause of hearing loss in the Indonesian population

The influence of genetic variation in oxidative stress genes on human noise susceptibility

Global and regional parameters of dyssynchrony in ischemic and nonischemic cardiomyopathy

Evaluation of intraventricular dyssynchrony in heart failure patients: A direct comparison between pulsed wave and color tissue Doppler imaging

Prevalence of mechanical dyssynchrony in patients with heart failure and preserved left ventricular function (a report from the Belgian Multicenter registry on dyssynchrony)

Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

DFNA5: hearing impairment exon instead of hearing impairment gene?

A novel Z-score-based method to analyze candidate genes for Age-Related Hearing Impairment

Nonsyndromic hearing loss

Age-related hearing impairment (ARHI): environmental risk factors and genetic prospects

A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment

GJB2 deafness gene shows a specific spectrum of mutations in Japan, including a frequent founder mutation

The WFS1 gene, responsible for low frequency sensorineural hearing loss and Wolfram syndrome, is expressed in a variety of inner ear cells

Longitudinal and cross-sectional phenotype analysis in a new, large dutch DFNA2/KCNQ4 family.

Further delineation of the DFNA5 phenotype: Results of speech recognition tests

Is DFNA5 a susceptibility gene for age-related hearing impairment?

DFNA10/EYA4 - the clinical picture.

A mutational hot spot in the KCNQ4 gene responsible for autosomal dominant hearing impairment.

Genes in the ear: what have we learned over the last years?

Speech recognition scores related to age and degree of hearing impairment in DFNA2/KCNQ4 and DFNA9/COCH.