Ghent University Academic Bibliography

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Current status and future expectations of nanobodies in oncology trials

Tessa De Pauw, Lynn De Mey, Jens Debacker (UGent) , Geert Raes, Jo Van Ginderachter (UGent) , Timo De Groof and Nick Devoogdt

(2023) EXPERT OPINION ON INVESTIGATIONAL DRUGS. 32(8). p.705-721
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Safety assessment of fluorescently labeled anti-EGFR Nanobodies in healthy dogs

Nayra Cristina Herreira do Valle (UGent) , Simone Janssen (UGent) , Marcus C. M. Stroet, Sofie Pollenus, Sonja Van den Block, Nick Devoogdt, Jens Debacker (UGent) , Sophie Hernot and Hilde De Rooster (UGent)

(2023) FRONTIERS IN PHARMACOLOGY. 14.
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- C3
Safety assessment of fluorescence-labeled anti-EGFR nanobody in healthy dogs

Nayra Cristina Herreira do Valle (UGent) , Simone Janssen (UGent) , Marcus Stroet, Sofie Pollenus, Sonja Van den Block, Nick Devoogdt, Jens Debacker (UGent) , Sophie Hernot and Hilde De Rooster (UGent)

(2023) EMIM 2023, European Molecular Imaging Meeting, Abstracts.
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Novel uPAR-targeting fluorescent single-domain antibodies as tools for in vivo optical cancer imaging

Lukasz Mateusiak, Sam Floru, Janne Wouters, Noemi B. Declerck, Eveline de Jonge-Muller, Simone Janssen (UGent) , Katty Zeven, Janik Puttemans, Nick Devoogdt and Sier C.F.M

(2023) Single-Domain Antibodies Conference 2023, Abstracts.
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In vivo optical imaging using a novel fluorescently-labeled single-domain antibody targeting a universal tumor marker

Lukasz Mateusiak, Sam Floru, Janne Wouters, Timo De Groof, Noemi Declerck, Simone Janssen (UGent) , Pieterjan Debie, Katty Zeven, Janik Puttemans, Karine Breckpot, et al.

(2023) Molecular-Guided Surgery : Molecules, Devices, and Applications IX. In Proceedings of SPIE 12361.
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In vivo optical imaging of glioma using a novel uPAR-targeting fluorescent single-domain antibody

Lukasz Mateusiak, Sam Floru, Timo De Groof, Noemi Declerck, Janne Wouters, Simone Janssen (UGent) , Pieterjan Debie, Katty Zeven, Cécile Vincke (UGent) , Janik Puttemans, et al.

(2023) EMIM 2023, European Molecular Imaging Meeting, Abstracts.
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Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

Thomas Ertveldt, Sofie Meulewaeter (UGent) , Yannick De Vlaeminck, Oscar Olarte, Katrijn Broos, Serge Van Calenbergh (UGent) , Stephanie Bourgeois, Joke Deprez (UGent) , Yves Heremans, Cleo Goyvaerts, et al.

(2023) THERANOSTICS. 13(15). p.5483-5500
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A comparison of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT with [18F]FDG-PET/CT in breast carcinoma patients

Odrade Gondry, Catarina Xavier, Johannes Heemskerk, Laurens Albert J Raes, Jens Debacker (UGent) , Frank De Geeter, Christel Fontaine, Marian Vanhoeij, SANDRINE ASPESLAGH (UGent) , Sofie Joris, et al.

(2023) EMIM 2023, European Molecular Imaging Meeting, Abstracts.
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CS1-specific single-domain antibodies labeled with actinium-225 prolong survival and increase CD8+T cells and PD-L1 expression in multiple myeloma

Kim De Veirman, Janik Puttemans, Ahmet Krasniqi, Thomas Ertveldt, Heleen Hanssens, Ema Romao, Dirk Hose, Cleo Goyvaert, Philip Vlummens (UGent) , Serge Muyldermans, et al.

(2021) ONCOIMMUNOLOGY. 10(1).
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Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade

Robin Maximilian Awad, Quentin Lecocq, Katty Zeven, Thomas Ertveldt, Lien De Beck, Hannelore Ceuppens, Katrijn Broos, Yannick De Vlaeminck, Cleo Goyvaerts, Magali Verdonck, et al.

(2021) MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 22. p.172-182
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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models

Bert Schepens (UGent) , Loes van Schie (UGent) , Wim Nerinckx (UGent) , Kenny Roose (UGent) , Wander Van Breedam (UGent) , Daria Fijalkowska (UGent) , Simon Devos (UGent) , Wannes Weyts (UGent) , Sieglinde De Cae (UGent) , Sandrine Vanmarcke (UGent) , et al.

(2021) SCIENCE TRANSLATIONAL MEDICINE. 13(621).
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Improved detection of molecular markers of atherosclerotic plaques using sub-millimeter PET imaging

Jessica Bridoux, Sara Neyt (UGent) , Pieterjan Debie, Benedicte Descamps (UGent) , Nick Devoogdt, Frederik Cleeren, Guy Bormans, Alexis Broisat, Vicky Caveliers, Catarina Xavier, et al.

(2020) MOLECULES. 25(8).
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Anti-human PD-L1 Nanobody for immuno-PET imaging : validation of a conjugation strategy for clinical translation

Jessica Bridoux, Katrijn Broos, Quentin Lecocq, Pieterjan Debie, Charlotte Martin, Steven Ballet, Geert Raes, Sara Neyt (UGent) , Christian Vanhove (UGent) , Karine Breckpot, et al.

(2020) BIOMOLECULES. 10(10).
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Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

Evangelia Bolli, Matthias D'Huyvetter, Aleksandar Murgaski, Danielle Berus, Geert Stange, Emile J Clappaert, Sana Arnouk, Ana Rita Pombo Antunes, Ahmet Krasniqi, Tony Lahoutte, et al.

(2019) JOURNAL OF CONTROLLED RELEASE. 314. p.1-11
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Theranostic radiolabeled anti-CD20 sdAb for targeted radionuclide therapy of non-Hodgkin lymphoma

Ahmet Krasniqi, Matthias D'Huyvetter, Catarina Xavier, Kevin Van der Jeught, Serge Muyldermans, José Van Der Heyden (UGent) , Tony Lahoutte, Jan Tavernier (UGent) and Nick Devoogdt

(2017) MOLECULAR CANCER THERAPEUTICS. 16(12). p.2828-2839
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AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

Adriaan Verhelle (UGent) , Nair Nisha, Inge Everaert (UGent) , Wouter Van Overbeke (UGent) , Lynn Supply (UGent) , Olivier Zwaenepoel (UGent) , Cindy Peleman, Jo Van Dorpe (UGent) , Tony Lahoutte, Nick Devoogdt, et al.

(2017) HUMAN MOLECULAR GENETICS. 26(7). p.1353-1364
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Rational design of Nanobody80 loop peptidomimetics : towards biased β2 adrenergic receptor ligands

Charlotte Martin, Samuel Moors, Mia Danielsen, Cecilia Betti, Cecilia Fabris, Daniel Sejer Pedersen, Els Pardon, Marion Peyressatre, Krisztina Fehér (UGent) , José Martins (UGent) , et al.

(2017) CHEMISTRY-A EUROPEAN JOURNAL. 23(40). p.9632-9640
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Non-invasive imaging of amyloid deposits in a mouse model of AGel using 99mTc-modified nanobodies and SPECT/CT

Adriaan Verhelle (UGent) , Wouter Van Overbeke (UGent) , Cindy Peleman, Rebecca De Smet (UGent) , Olivier Zwaenepoel (UGent) , Tony Lahoutte, Jo Van Dorpe (UGent) , Nick Devoogdt and Jan Gettemans (UGent)

(2016) MOLECULAR IMAGING AND BIOLOGY. 18(6). p.887-897
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Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Charlotte Scott (UGent) , Fang Zheng, Patrick De Baetselier, Liesbet Martens (UGent) , Yvan Saeys (UGent) , Sofie De Prijck (UGent) , Saskia Lippens (UGent) , Chloé Abels, Steve Schoonooghe, Geert Raes, et al.

(2016) NATURE COMMUNICATIONS. 7.
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Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

Gezim Bala, Anneleen Blykers, Catarina Xavier, Benedicte Descamps (UGent) , Alexis Broisat, Catherine Ghezzi, Daniel Fagret, Guy Van Camp, Vicky Caveliers, Christian Vanhove (UGent) , et al.

(2016) EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. 17(9). p.1001-1008
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Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

Gezim Bala, Anneleen Blykers, Catarina Xavier, Benedicte Descamps (UGent) , Alexis Broisat, Catherine Ghezzi, Daniel Fagret, Guy Van Camp, Vicky Caveliers, Christian Vanhove (UGent) , et al.

(2016) ACTA CARDIOLOGICA. 71(1). p.82-83
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Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8

Delphine Demeestere (UGent) , Eline Dejonckheere (UGent) , Sophie Steeland (UGent) , Paco Hulpiau (UGent) , Jurgen Haustraete (UGent) , Nick Devoogdt, Rielana Wichert, Christoph Becker-Pauly, Elien Van Wonterghem (UGent) , Sylviane Dewaele (UGent) , et al.

(2016) MOLECULAR THERAPY. 24(5). p.890-902
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Sortase a-mediated site-specific labeling of camelid single-domain antibody-fragments : a versatile strategy for multiple molecular imaging modalities

Sam Massa, Niravkumar Vikani, Cecilia Betti, Steven Ballet, Saskia Vanderhaegen, Jan Steyaert, Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Anton Bunschoten, Fijs van Leeuwen, et al.

(2016) CONTRAST MEDIA & MOLECULAR IMAGING. 11(5). p.328-339
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Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma

Marleen Keyaerts, Catarina Xavier, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Chloé Ackaert, Marian Vanhoeij, Francois Duhoux, Thierry Gevaert, Philippe Simon, et al.

(2016) JOURNAL OF NUCLEAR MEDICINE. 57(1). p.27-33
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Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1

Sophie Steeland (UGent) , Leen Puimège (UGent) , Roosmarijn Vandenbroucke (UGent) , Filip Van Hauwermeiren (UGent) , Jurgen Haustraete (UGent) , Nick Devoogdt, Paco Hulpiau (UGent) , Geert Leroux-Roels (UGent) , Debby Laukens (UGent) , Philip Meuleman (UGent) , et al.

(2015) JOURNAL OF BIOLOGICAL CHEMISTRY. 290(7). p.4022-4037
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18F-anti-VCAM-1 nanobody for PET/CT imaging of inflamed atherosclerotic plaque

Gezim Bala, Anneleen Blykers, Catarina Xavier, Benedicte Descamps (UGent) , Nick Devoogdt, Christian Vanhove (UGent) , Tony Lahoutte, Guy van Camp, Steven Droogmans, Bernard Cosyns, et al.

(2014) European Molecular Imaging Meeting, Abstracts.
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Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy

Lea Olive Tchouate Gainkam, Marleen Keyaerts, Vicky Caveliers, Nick Devoogdt, Christian Vanhove (UGent) , Leo Van Grunsven, Serge Muylderman and Tony Lahoutte

(2011) MOLECULAR IMAGING AND BIOLOGY. 13(5). p.940-948
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Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice

Lea Olive Tchouate Gainkam, Vicky Caveliers, Nick Devoogdt, Christian Vanhove (UGent) , Catarina Xavier, Otto Boerman, Serge Muylderman, Axel Bossuy and Tony Lahoutte

(2011) CONTRAST MEDIA & MOLECULAR IMAGING. 6(2). p.85-92

Academic Bibliography

Current status and future expectations of nanobodies in oncology trials

Safety assessment of fluorescently labeled anti-EGFR Nanobodies in healthy dogs

Safety assessment of fluorescence-labeled anti-EGFR nanobody in healthy dogs

Novel uPAR-targeting fluorescent single-domain antibodies as tools for in vivo optical cancer imaging

In vivo optical imaging using a novel fluorescently-labeled single-domain antibody targeting a universal tumor marker

In vivo optical imaging of glioma using a novel uPAR-targeting fluorescent single-domain antibody

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

A comparison of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT with [18F]FDG-PET/CT in breast carcinoma patients

CS1-specific single-domain antibodies labeled with actinium-225 prolong survival and increase CD8+T cells and PD-L1 expression in multiple myeloma

Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade

An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models

Improved detection of molecular markers of atherosclerotic plaques using sub-millimeter PET imaging

Anti-human PD-L1 Nanobody for immuno-PET imaging : validation of a conjugation strategy for clinical translation

Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

Theranostic radiolabeled anti-CD20 sdAb for targeted radionuclide therapy of non-Hodgkin lymphoma

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

Rational design of Nanobody80 loop peptidomimetics : towards biased β2 adrenergic receptor ligands

Non-invasive imaging of amyloid deposits in a mouse model of AGel using 99mTc-modified nanobodies and SPECT/CT

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8

Sortase a-mediated site-specific labeling of camelid single-domain antibody-fragments : a versatile strategy for multiple molecular imaging modalities

Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1

18F-anti-VCAM-1 nanobody for PET/CT imaging of inflamed atherosclerotic plaque

Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy

Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice

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