Ghent University Academic Bibliography

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Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics

Jana Ramon (UGent) , Yanou Engelen (UGent) , Herlinde De Keersmaecker (UGent) , Ilia Goemaere (UGent) , Deep Punj (UGent) , Julián Mejía Morales (UGent) , Cédric Bonte, Geert Berx (UGent) , Esther Hoste (UGent) , Stephan Stremersch, et al.

(2024) JOURNAL OF CONTROLLED RELEASE. 365. p.1019-1036
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Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery

Bram Bogaert (UGent) , Aliona Debisschop (UGent) , Thomas Ehouarne (UGent) , Hannelore Van Eeckhoutte (UGent) , Joyceline De Volder (UGent) , An Jacobs, Eline Pottie (UGent) , Riet De Rycke (UGent) , Aurélie Crabbé (UGent) , Pieter Mestdagh (UGent) , et al.

(2024) Nano Letters. 24(10). p.2961-2971
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Considerations on the design of lipid-based mRNA vaccines against cancer

Sofie Meulewaeter (UGent) , Yao Zhang, Abishek Wadhwa, Kevin Fox, Ine Lentacker (UGent) , Kenneth W. Harder, Pieter R. Cullis, Stefaan De Smedt (UGent) , Miffy H.Y. Cheng and Rein Verbeke (UGent)

(2024) JOURNAL OF MOLECULAR BIOLOGY. 436(2).
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Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

Sofie Meulewaeter (UGent) , Gust Nuytten (UGent) , Miffy H.Y. Cheng, Stefaan De Smedt (UGent) , Pieter R. Cullis, Thomas De Beer (UGent) , Ine Lentacker (UGent) and Rein Verbeke (UGent)

(2023) JOURNAL OF CONTROLLED RELEASE. 357. p.149-160
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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

Joke Deprez (UGent) , Rein Verbeke (UGent) , Sofie Meulewaeter (UGent) , Ilke Aernout (UGent) , Heleen Dewitte (UGent) , Tine Decruy (UGent) , Julie Coudenys (UGent) , Julie Van Duyse (UGent) , Gert Van Isterdael (UGent) , Dan Peer, et al.

(2023) NATURE NANOTECHNOLOGY. 18. p.1341-1350
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Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

Thomas Ertveldt, Sofie Meulewaeter (UGent) , Yannick De Vlaeminck, Oscar Olarte, Katrijn Broos, Serge Van Calenbergh (UGent) , Stephanie Bourgeois, Joke Deprez (UGent) , Yves Heremans, Cleo Goyvaerts, et al.

(2023) THERANOSTICS. 13(15). p.5483-5500
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Fluorine MR imaging probes dynamic migratory profiles of perfluorocarbon-loaded dendritic cells after streptozotocin-induced inflammation

Shweta Saini, An-Sofie Vanherwegen, Sayuan Liang, Rein Verbeke (UGent) , Hannelie Korf, Ine Lentacker (UGent) , Stefaan De Smedt (UGent) , Conny Gysemans and Uwe Himmelreich

(2022) MOLECULAR IMAGING AND BIOLOGY. 24(2). p.321-332
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Evaluation of liposome-loaded microbubbles as a theranostic tool in a murine collagen-induced arthritis model

Joke Deprez (UGent) , Silke Roovers, Guillaume Lajoinie, Heleen Dewitte (UGent) , Tine Decruy (UGent) , Julie Coudenys (UGent) , Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Michel Versluis, Dirk Elewaut (UGent) , et al.

(2022) SCIENTIA PHARMACEUTICA. 90(1).
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Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

Rupert Mayer (UGent) , Rein Verbeke (UGent) , Caroline Asselman (UGent) , Ilke Aernout (UGent) , Adillah Gul (UGent) , Denzel Eggermont (UGent) , Katie Boucher (UGent) , Fabien Henri Thery (UGent) , Teresa Maia (UGent) , Hans Demol (UGent) , et al.

(2022) NATURE COMMUNICATIONS. 13(1).
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Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer

Ragna Haegebaert (UGent) , Maxime Kempers, Wim Ceelen (UGent) , Ine Lentacker (UGent) and Katrien Remaut (UGent)

(2022) EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 172. p.16-30
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Physical transfection technologies for macrophages and dendritic cells in immunotherapy

Aranit Harizaj (UGent) , Stefaan De Smedt (UGent) , Ine Lentacker (UGent) and Kevin Braeckmans (UGent)

(2021) EXPERT OPINION ON DRUG DELIVERY. 18(2). p.229-247
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The dawn of mRNA vaccines : the COVID-19 case

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2021) JOURNAL OF CONTROLLED RELEASE. 333. p.511-520
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mRNA in cancer immunotherapy : beyond a source of antigen

Lien Van Hoecke (UGent) , Rein Verbeke (UGent) , Heleen Dewitte (UGent) , Ine Lentacker (UGent) , Karim Vermaelen (UGent) , Karine Breckpot and Sandra Van Lint (UGent)

(2021) MOLECULAR CANCER. 20(1).
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Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

An-Katrien Minnaert (UGent) , Helena Vanluchene (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Stefaan De Smedt (UGent) , Koen Raemdonck (UGent) , Niek Sanders (UGent) and Katrien Remaut (UGent)

(2021) ADVANCED DRUG DELIVERY REVIEWS. 176.
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Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells

Aranit Harizaj (UGent) , Mike Wels (UGent) , Laurens Raes, Stephan Stremersch (UGent) , Glenn Goetgeluk (UGent) , Toon Brans (UGent) , Bart Vandekerckhove (UGent) , Félix Sauvage (UGent) , Stefaan De Smedt (UGent) , Ine Lentacker (UGent) , et al.

(2021) ADVANCED FUNCTIONAL MATERIALS. 31(28).
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Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells

Aranit Harizaj (UGent) , Benedicte Descamps (UGent) , Christophe Mangodt (UGent) , Stephan Stremersch (UGent) , Arianna Stoppa, Lieve Balcaen (UGent) , Toon Brans (UGent) , Hilde De Rooster (UGent) , Nausikaa Devriendt (UGent) , Juan Fraire (UGent) , et al.

(2021) BIOMATERIALS SCIENCE. 9(11). p.4005-4018
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Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger

Aranit Harizaj (UGent) , Filip Van Hauwermeiren (UGent) , Stephan Stremersch (UGent) , Riet De Rycke (UGent) , Herlinde De Keersmaecker (UGent) , Toon Brans (UGent) , Juan Fraire (UGent) , Karolien Grauwen, Stefaan De Smedt (UGent) , Ine Lentacker (UGent) , et al.

(2021) NANOSCALE. 13(13). p.6592-6604
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Opening doors with ultrasound and microbubbles : beating biological barriers to promote drug delivery

Joke Deprez (UGent) , G. Lajoinie, Yanou Engelen (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2021) ADVANCED DRUG DELIVERY REVIEWS. 172. p.9-36
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Ultrasound-responsive cavitation nuclei for therapy and drug delivery

Klazina Kooiman, Silke Roovers, Simone A. G. Langeveld, Robert T. Kleven, Heleen Dewitte (UGent) , Meaghan A. O'Reilly, Jean-Michel Escoffre, Ayache Bouakaz, Martin D. Verweij, Kullervo Hynynen, et al.

(2020) ULTRASOUND IN MEDICINE AND BIOLOGY. 46(6). p.1296-1325
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mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Lien Van Hoecke (UGent) , Rein Verbeke (UGent) , Dorien De Vlieger, Heleen Dewitte (UGent) , Kenny Roose (UGent) , Sharon Van Nevel (UGent) , Olga Krysko (UGent) , Claus Bachert (UGent) , Bert Schepens (UGent) , Ine Lentacker (UGent) , et al.

(2020) MOLECULAR THERAPY-NUCLEIC ACIDS. 20. p.777-787
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Trap levels in persistent phosphors for bio-imaging

Dirk Poelman (UGent) , Olivier De Clercq, Jiaren Du, Aranit Harizaj (UGent) , Ine Lentacker (UGent) and Kevin Braeckmans (UGent)

(2019) Photonic Materials, 8th South African conference, Abstracts. p.29-29
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Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound

Silke Roovers, Joke Deprez (UGent) , D Priwitaningrum, G Lajoinie, N Rivron, Heidi Declercq (UGent) , Olivier De Wever (UGent) , E Stride, S Le Gac, M Versluis, et al.

(2019) JOURNAL OF CONTROLLED RELEASE. 316. p.79-92
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Longitudinal in vivo assessment of host-microbe interactions in a murine model of pulmonary aspergillosis

Shweta Saini, Jennifer Poelmans, Hannelie Korf, James L. Dooley, Sayuan Liang, Bella B. Manshian, Rein Verbeke (UGent) , Stefaan J. Soenen, Greetje Vande Velde, Ine Lentacker (UGent) , et al.

(2019) ISCIENCE. 20. p.184-194
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Biocompatible lipid‐coated persistent luminescent nanoparticles for in vivo imaging of dendritic cell migration

Aranit Harizaj (UGent) , Olivier De Clercq, Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Stefaan De Smedt (UGent) , Dirk Poelman (UGent) , Ine Lentacker (UGent) and Kevin Braeckmans (UGent)

(2019) PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION. 36(11).
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Enhancing nucleic acid delivery with ultrasound and microbubbles

Heleen Dewitte (UGent) , Silke Roovers, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2019) Nanotechnology for nucleic acid delivery : methods and protocols. In Methods in Molecular Biology 1943. p.241-251
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Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Karine Breckpot, Jonas Janssens, Serge Van Calenbergh (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2019) ACS NANO. 13(2). p.1655-1669
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Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model

Shweta Saini, Hannelie Korf, Sayuan Liang, Rein Verbeke (UGent) , Bella Manshian, Koen Raemdonck (UGent) , Ine Lentacker (UGent) , Conny Gysemans, Stefaan De Smedt (UGent) and Uwe Himmelreich

(2019) MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 32(3). p.295-305
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Three decades of messenger RNA vaccine development

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2019) NANO TODAY. 28.
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Sonoprinting of nanoparticle-loaded microbubbles : unraveling the multi-timescale mechanism

Silke Roovers, Guillaume Lajoinie, Ine De Cock, Toon Brans (UGent) , Heleen Dewitte (UGent) , Kevin Braeckmans (UGent) , Michel Versuis, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2019) BIOMATERIALS. 217.
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The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation

Silke Roovers, Tim Segers, Guillaume Lajoinie, Joke Deprez (UGent) , Michel Versluis, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2019) LANGMUIR. 35(31). p.10173-10191
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Tri-modal in vivo imaging of pancreatic islets transplanted subcutaneously in mice

Sayuan Liang, Karim Louchami, Bryan Holvoet, Rein Verbeke (UGent) , Christophe M Deroose, Bella Manshian, Stefaan J Soenen, Ine Lentacker (UGent) and Uwe Himmelreich

(2018) MOLECULAR IMAGING AND BIOLOGY. 20(6). p.940-951
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Optimized messenger RNA immunolipoplexes for cancer immunotherapy : balancing immunogenicity and adjuvancy

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Karine Breckpot, Serge Van Calenbergh (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2018) Cancer Immunotherapy, 4th CRI-CIMT-EATI-AACR international conference, Abstracts.
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Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles

Guillaume Lajoinie, Ying Luan, Erik Gelderblom, Benjamin Dollet, Frits Mastik, Heleen Dewitte (UGent) , Ine Lentacker (UGent) , Nico de Jong and Michel Versluis

(2018) COMMUNICATIONS PHYSICS. 1.
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Co-delivery of nucleoside-modified mRNA and immunomodulators for cancer immunotherapy: restoring the immunogenicity of immunosilent mRNA

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Laura Wayteck (UGent) , Karine Breckpot, Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2017) mRNA Health, 5th International conference, Abstracts.
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mRNA-based nanoparticles for therapeutic cancer vaccination

Rein Verbeke (UGent) , Laura Wayteck (UGent) , Karine Breckpot, Christian Vanhove (UGent) , Benedicte Descamps (UGent) , Stefaan De Smedt (UGent) , Heleen Dewitte (UGent) and Ine Lentacker (UGent)

(2017) mRNA therapeutics : advances and perspectives, Le Studium international conference, Abstracts.
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Dynamic fluorescence microscopy of cellular uptake of intercalating model drugs by ultrasound-activated microbubbles

BHA Lammertink, R Deckers, M Derieppe, Ine De Cock (UGent) , Ine Lentacker (UGent) , G Storm, CTW Moonen and C Bos

(2017) MOLECULAR IMAGING AND BIOLOGY. 19(5). p.683-693
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Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy : restoring the immunogenicity of immunosilent mRNA

Rein Verbeke (UGent) , Ine Lentacker (UGent) , Laura Wayteck (UGent) , Karine Breckpot, Mieke Van Bockstal (UGent) , Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Stefaan De Smedt (UGent) and Heleen Dewitte (UGent)

(2017) JOURNAL OF CONTROLLED RELEASE. 266. p.287-300
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In vitro methods to study bubble-cell interactions : fundamentals and therapeutic applications

Guillaume Lajoinie, Ine De Cock (UGent) , Constantin C Coussios, Ine Lentacker (UGent) , Séverine Le Gac, Eleanor Stride and Michel Versluis

(2016) BIOMICROFLUIDICS. 10(1).
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Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

Katrijn Broos, Kevin Vanderjeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Kris Thielemans and Karine Breckpot

(2016) MOLECULAR THERAPY-NUCLEIC ACIDS. 5.
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Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles

Ine De Cock (UGent) , Guillaume Lajoinie, Michel Versluis, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2016) BIOMATERIALS. 83. p.294-307
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Immunogenic mRNA nanoparticles for dendritic cell-based cancer vaccination

Rein Verbeke (UGent) , Heleen Dewitte (UGent) , Ine Lentacker (UGent) and Stefaan De Smedt (UGent)

(2015) Cancer Vaccine Conference Amsterdam, Abstracts.
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Evaluation of mRNA lipoplexes for single-step antigen loading and maturation of dendritic cells in cancer immunotherapy

Rein Verbeke (UGent) , Heleen Dewitte (UGent) , Ine Lentacker (UGent) and Stefaan De Smedt (UGent)

(2015) mRNA Health, 3rd International conference, Abstracts.
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Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells

Ranhua Xiong (UGent) , Koen Raemdonck (UGent) , Karen Peynshaert (UGent) , Ine Lentacker (UGent) , Ine De Cock (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Andre Skirtach (UGent) and Kevin Braeckmans (UGent)

(2015) Proceedings of SPIE. In Proceedings of SPIE 9338.
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Theranostic mRNA-loaded microbubbles in the lymphatics of dogs: implications for drug delivery

Heleen Dewitte (UGent) , Katrien Vanderperren (UGent) , Hendrik Haers (UGent) , Emmelie Stock (UGent) , Luc Duchateau (UGent) , Myriam Hesta (UGent) , Jimmy Saunders (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2015) THERANOSTICS. 5(1). p.97-109
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Microbubbles as magic bullets in cancer immunotherapy

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Katrien Vanderperren (UGent) , Hendrik Haers (UGent) , Emmelie Stock (UGent) , Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2015) Ultrasound Contrast Imaging, 20th European symposium, Program and abstractbook. p.34-36
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The ReNAissanCe of mRNA-based cancer therapy

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Heleen Dewitte (UGent) , Ine Lentacker (UGent) , Carlo Heirman, Karine Breckpot and Kris Thielemans

(2015) EXPERT REVIEW OF VACCINES. 14(2). p.235-251
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Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis

Ine De Cock (UGent) , Elisa Zagato (UGent) , Kevin Braeckmans (UGent) , Ying Luan, Nico de Jong, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2015) JOURNAL OF CONTROLLED RELEASE. 197. p.20-28
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Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro

Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Karine Breckpot, Roosmarijn Vandenbroucke (UGent) , Claude Libert (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 195. p.138-146
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The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Katrien Vanderperren (UGent) , Kris Thielemans, Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) Controlled Drug Delivery, 13th European symposium, Abstracts. p.94-95
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The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Katrien Vanderperren (UGent) , Kris Thielemans, Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) Le Tours de microbubbels, Posters.
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The bubble breakthrough in cancer immunotherapy

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Katrien Vanderperren (UGent) , Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) Knowledge for Growth, Abstracts.
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Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment

Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Karine Breckpot, Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2014) NANO TODAY. 9(6). p.743-758
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The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans, Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 194. p.28-36
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Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells

Ranhua Xiong (UGent) , Koen Raemdonck (UGent) , Karen Peynshaert (UGent) , Ine Lentacker (UGent) , Ine De Cock (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Andre Skirtach (UGent) and Kevin Braeckmans (UGent)

(2014) ACS NANO. 8(6). p.6288-6296
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Understanding ultrasound induced sonoporation: definitions and underlying mechanisms

Ine Lentacker (UGent) , Ine De Cock, R Deckers, Stefaan De Smedt (UGent) and CTW Moonen

(2014) ADVANCED DRUG DELIVERY REVIEWS. 72. p.49-64
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Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery

Bart Geers (UGent) , Olivier De Wever (UGent) , Jo Demeester (UGent) , Marc Bracke (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2013) SMALL. 9(23). p.4027-4035
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Enhancing nucleic acid delivery with ultrasound and microbubbles

Steven Cool, Bart Geers (UGent) , Ine Lentacker (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2013) Nanotechnology for nucleic acid delivery : methods and protocols. In Methods in Molecular Biology 948. p.195-204
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Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and 19F-MRI tracking of dendritic cells

Heleen Dewitte (UGent) , Bart Geers (UGent) , Sayuan Liang, Uwe Himmelreich, Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2013) JOURNAL OF CONTROLLED RELEASE. 169(1-2). p.141-149
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Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB opening

Angelika Alonso, Eileen Reinz, Barbara Leuchs, Juergen Kleinschmidt, Marc Fatar, Bart Geers (UGent) , Ine Lentacker (UGent) , Michael G. Hennerici, Stefaan De Smedt (UGent) and Stephen Meairs

(2013) MOLECULAR THERAPY-NUCLEIC ACIDS. 2.
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The mechanisms behind sonoporation through the eyes of an AAV-vector

Bart Geers (UGent) , Ine Lentacker (UGent) , Angelika Alonso, Niek Sanders (UGent) , Jo Demeester (UGent) , Stephen Meairs and Stefaan De Smedt (UGent)

(2012) PUBLICATIONS QUARTERLY / AMERICAN CHEMICAL SOCIETY.
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Crucial factors and emerging concepts in ultrasound-triggered drug delivery

Bart Geers (UGent) , Heleen Dewitte (UGent) , Stefaan De Smedt (UGent) and Ine Lentacker (UGent)

(2012) JOURNAL OF CONTROLLED RELEASE. 164(3). p.248-255
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mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells

Marie-Luce De Temmerman (UGent) , Heleen Dewitte (UGent) , Roosmarijn Vandenbroucke (UGent) , Bart Lucas (UGent) , Claude Libert (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Ine Lentacker (UGent) and Joanna Rejman (UGent)

(2011) BIOMATERIALS. 32(34). p.9128-9135
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Self-assembled liposome-loaded microbubbles: the missing link for safe and efficient ultrasound triggered drug-delivery

Bart Geers (UGent) , Ine Lentacker (UGent) , Niek Sanders (UGent) , Jo Demeester (UGent) , Stephen Meairs and Stefaan De Smedt (UGent)

(2011) JOURNAL OF CONTROLLED RELEASE. 152(2). p.249-256
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- Journal Article
- A1
Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles

Bart Geers (UGent) , Ine Lentacker (UGent) , Angelika Alonso, Niek Sanders (UGent) , Jo Demeester (UGent) , Stephen Meairs and Stefaan De Smedt (UGent)

(2011) MOLECULAR PHARMACEUTICS. 8(6). p.2244-2251
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- Journal Article
- A1
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved

Ine Lentacker (UGent) , Bart Geers (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2010) MOLECULAR THERAPY. 18(1). p.101-108
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- Journal Article
- A1
Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes

Ine Lentacker (UGent) , Nan Wang (UGent) , Roosmarijn Vandenbroucke (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2009) MOLECULAR PHARMACEUTICS. 6(2). p.457-467
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Drug loaded microbubble design for ultrasound triggered delivery

Ine Lentacker (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2009) SOFT MATTER. 5(11). p.2161-2170
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- PhD Thesis
- open access
Design and evaluation of drug loaded microbubbles for ultrasound guided cancer therapy

Ine Lentacker (UGent)

(2009)
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- Journal Article
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New strategies for nucleic acid delivery to conquer cellular and nuclear membranes

Ine Lentacker (UGent) , Roosmarijn Vandenbroucke (UGent) , Bart Lucas (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2008) Journal of Controlled Release. 132(3). p.279-288
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- Journal Article
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Can ultrasound solve the transport barrier of the neural retina?

Liesbeth Peeters (UGent) , Ine Lentacker (UGent) , Roosmarijn Vandenbroucke (UGent) , Bart Lucas (UGent) , Jo Demeester (UGent) , Niek Sanders (UGent) and Stefaan De Smedt (UGent)

(2008) PHARMACEUTICAL RESEARCH. 25(11). p.2657-2665
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- A1
- open access
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles

Roosmarijn Vandenbroucke (UGent) , Ine Lentacker (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2008) JOURNAL OF CONTROLLED RELEASE. 126(3). p.265-273
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- Conference Paper
- C1
Loading of PEGylated siRNA lipoplexes on microbubbles restores their siRNA delivery capacity in the presence of ultrasound

Roosmarijn Vandenbroucke (UGent) , Ine Lentacker (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2008) HUMAN GENE THERAPY. 18(10). p.1046-1046
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- Conference Paper
- C3
Circumventing the endocytotic uptake of highly PEGylated lipoplexes by using lipoplex loaded microbubbles and ultrasound can drastically increase their transfection efficiency

Ine Lentacker (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2008) Human Gene Therapy. 19(10). p.1095-1095
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Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer

Niek Sanders (UGent) , Liesbeth Peeters, Ine Lentacker (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2007) JOURNAL OF CONTROLLED RELEASE. 122(3). p.226-235
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Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound

Ine Lentacker (UGent) , Stefaan De Smedt (UGent) , Jo Demeester (UGent) , Veerle Van Marck (UGent) , Marc Bracke (UGent) and Niek Sanders (UGent)

(2007) ADVANCED FUNCTIONAL MATERIALS. 17(12). p.1910-1916
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Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA

Ine Lentacker (UGent) , Bruno De Geest (UGent) , Roosmarijn Vandenbroucke (UGent) , Liesbeth Peeters, Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Niek Sanders (UGent)

(2006) LANGMUIR. 22(17). p.7273-7278
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- Conference Paper
- C3
- open access
Microbubbles which bind and protect DNA against nucleases

Ine Lentacker (UGent) , Stefaan De Smedt (UGent) , Jo Demeester (UGent) and Niek Sanders (UGent)

(2006) Journal of controlled release. 116(2). p.e73-e75

Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics

Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery

Considerations on the design of lipid-based mRNA vaccines against cancer

Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

Fluorine MR imaging probes dynamic migratory profiles of perfluorocarbon-loaded dendritic cells after streptozotocin-induced inflammation

Evaluation of liposome-loaded microbubbles as a theranostic tool in a murine collagen-induced arthritis model

Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer

Physical transfection technologies for macrophages and dendritic cells in immunotherapy

The dawn of mRNA vaccines : the COVID-19 case

mRNA in cancer immunotherapy : beyond a source of antigen

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells

Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger

Opening doors with ultrasound and microbubbles : beating biological barriers to promote drug delivery

Ultrasound-responsive cavitation nuclei for therapy and drug delivery

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Trap levels in persistent phosphors for bio-imaging

Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound

Longitudinal in vivo assessment of host-microbe interactions in a murine model of pulmonary aspergillosis

Biocompatible lipid‐coated persistent luminescent nanoparticles for in vivo imaging of dendritic cell migration

Enhancing nucleic acid delivery with ultrasound and microbubbles

Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells

Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model

Three decades of messenger RNA vaccine development

Sonoprinting of nanoparticle-loaded microbubbles : unraveling the multi-timescale mechanism

The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation

Tri-modal in vivo imaging of pancreatic islets transplanted subcutaneously in mice

Optimized messenger RNA immunolipoplexes for cancer immunotherapy : balancing immunogenicity and adjuvancy

Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles

Co-delivery of nucleoside-modified mRNA and immunomodulators for cancer immunotherapy: restoring the immunogenicity of immunosilent mRNA

mRNA-based nanoparticles for therapeutic cancer vaccination

Dynamic fluorescence microscopy of cellular uptake of intercalating model drugs by ultrasound-activated microbubbles

Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy : restoring the immunogenicity of immunosilent mRNA

In vitro methods to study bubble-cell interactions : fundamentals and therapeutic applications

Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles

Immunogenic mRNA nanoparticles for dendritic cell-based cancer vaccination

Evaluation of mRNA lipoplexes for single-step antigen loading and maturation of dendritic cells in cancer immunotherapy

Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells

Theranostic mRNA-loaded microbubbles in the lymphatics of dogs: implications for drug delivery

Microbubbles as magic bullets in cancer immunotherapy

The ReNAissanCe of mRNA-based cancer therapy

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis

Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro

The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination

The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination

The bubble breakthrough in cancer immunotherapy

Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells

Understanding ultrasound induced sonoporation: definitions and underlying mechanisms

Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery

Enhancing nucleic acid delivery with ultrasound and microbubbles

Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and 19F-MRI tracking of dendritic cells

Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB opening

The mechanisms behind sonoporation through the eyes of an AAV-vector

Crucial factors and emerging concepts in ultrasound-triggered drug delivery

mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells

Self-assembled liposome-loaded microbubbles: the missing link for safe and efficient ultrasound triggered drug-delivery

Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles

Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved

Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes

Drug loaded microbubble design for ultrasound triggered delivery

Design and evaluation of drug loaded microbubbles for ultrasound guided cancer therapy

New strategies for nucleic acid delivery to conquer cellular and nuclear membranes

Can ultrasound solve the transport barrier of the neural retina?

Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles

Loading of PEGylated siRNA lipoplexes on microbubbles restores their siRNA delivery capacity in the presence of ultrasound

Circumventing the endocytotic uptake of highly PEGylated lipoplexes by using lipoplex loaded microbubbles and ultrasound can drastically increase their transfection efficiency

Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer

Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound

Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA

Microbubbles which bind and protect DNA against nucleases