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New paradigm in NKT cell antigens : MCS-0208 (2-(hydroxymethyl)phenylthio-phytoceramide) - an aryl-phytoceramide compound with a single hydroxyl group stimulates NKT cells
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Commensal-driven immune zonation of the liver promotes host defence
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MAIT cells come to the rescue in cancer immunotherapy?
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A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides
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A natural killer T-cell subset that protects against airway hyperreactivity
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4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies
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Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha
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Adipose tissue macrophages and their polarization in health and obesity
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Galactosylsphingamides : new α-GalCer analogues to probe the F’-pocket of CD1d
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Double-negative T resident memory cells of the lung react to influenza virus infection via CD11chi dendritic cells
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What rheumatologists need to know about innate lymphocytes
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Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma?
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New immune cells in spondyloarthritis: key players or innocent bystanders?
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Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists
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- Journal Article
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Lipid and carbohydrate modifications of α-galactosylcer-amide differently influence mouse and human type I natural killer T cell activation
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An optimized method for isolating and expanding invariant natural killer T cells from mouse spleen
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An in silico approach for modelling T-helper polarizing iNKT cell agonists
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The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid
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- Journal Article
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Preclinical evaluation of invariant natural killer T cells in the 5T33 multiple myeloma model
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Microbes, the gut and ankylosing spondylitis
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Natural killer T cells: born in the thymus, raised in the gut
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Crystal structures of bovine CD1d reveal altered αGalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids
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Structural basis for the recognition of C20:2-αGalCer by the invariant natural killer T-cell receptor-like antibody L363
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Regulating the regulators: SOCS3 joins the dance
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Mechanisms regulating TNF-driven gut and joint inflammation
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Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis
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Divergent synthetic approach to 6''-modified α-GalCer analogues
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The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000
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Synthesis and in vivo evaluation of 4-Deoxy-4,4-difluoro-KRN7000
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Synthesis and in vitro evaluation of α-GalCer epimers
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Randomized placebo controlled phase I/II trial of α-galactosylceramide for the treatment of chronic hepatitis C
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NKT cells: manipulable managers of joint inflammation