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Inhibition of the protein arginine methyltransferase PRMT5 in high-risk multiple myeloma as a novel treatment approach
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Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
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- Journal Article
- A2
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The plant anaphase promoting-complex/cyclosome
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Microscopic visualization of cell-cell adhesion complexes at micro and nanoscale
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CRISPR/Cas gene editing in the human germline
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Fertilization failure after human ICSI and the clinical potential of PLCZ1
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Emerging in vitro platforms and omics technologies for studying the endometrium and early embryo-maternal interface in humans
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Fetal germ cell development in humans, a link with infertility
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CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out
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Partial EMT takes the lead in cancer metastasis
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DNA methylation regulates transcription factor-specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon
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The lack of a representative tendinopathy model hampers fundamental mesenchymal stem cell research
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Long-read sequencing to unravel complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss
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A reflux-and-growth mechanism explains oscillatory patterning of lateral root branching sites
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Testosterone therapy and its monitoring in adolescent boys with hypogonadism : results of an international survey from the I-DSD Registry
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Ion mobility coupled to a time-of-flight mass analyzer combined with fragment intensity predictions improves identification of classical bioactive peptides and small open reading frame-encoded peptides
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Rare modifier variants alter the severity of cardiovascular disease in pseudoxanthoma elasticum : identification of novel candidate modifier genes and disease pathways through mixture of effects analysis
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Ligand-receptor interactions elucidate sex-specific pathways in the trajectory from primordial germ cells to gonia during human development
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Deep learning is widely applicable to phenotyping embryonic development and disease
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Alobar holoprosencephaly in mining‐related areas of the Eastern region of the Democratic Republic of the Congo : a case series
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Insect midgut cell cultures to study and optimize cellular uptake of dsRNA for RNAi-mediated pest control
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Clinical findings and follow-up of 46,XY and 45,X/46,XY testicular dysgenesis
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Combinatorial control of plant specialized metabolism : mechanisms, functions, and consequences
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α-Actinin-4 promotes the progression of prostate cancer through the Akt/GSK-3β/β-catenin signaling pathway
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PHF6 expression levels impact human hematopoietic stem cell differentiation
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TRAIL receptors serve as stress-associated molecular patterns to promote ER-stress-induced inflammation
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Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice
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Steroid synthesis and metabolism in the equine placenta during placentitis
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The dynamic nature and regulation of the root clock
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- Journal Article
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b3galt6 Knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region
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N-cadherin stabilises neural identity by dampening anti-neural signals
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Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells
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Update on mammalian sperm capacitation : how much does the horse differ from other species?
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Specific distribution of glycan motifs at the surface of midgut cells in the cotton leafworm
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Connexin hemichannels and cell death as measures of bovine COC vitrification success
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Tackling plant phosphate starvation by the roots
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Functional analysis of Arabidopsis and maize transgenic lines overexpressing the ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7
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Transcriptional networks orchestrating programmed cell death during plant development
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The zebrafish as an emerging model to study DNA damage in aging, cancer and other diseases
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Unraveling a local inhibitory mechanism safeguarding regular lateral root spacing
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Involving Individuals with disorders of sex development and their parents in exploring new models of shared learning : proceedings from a dsdnet cost action workshop
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Histological assessment of gonads in DSD : relevance for clinical management
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The circadian clock sets the time of DNA replication licensing to regulate growth in Arabidopsis
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Regulation of intercellular TARGET OF MONOPTEROS 7 protein transport in the Arabidopsis root
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- Journal Article
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Importance of validating antibodies and small compound inhibitors using genetic knockout studies : T cell receptor-induced CYLD phosphorylation by IKKε/TBK1 as a case study
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Reactive oxygen species in plant development
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Fox proteins are modular competency factors for facial cartilage and tooth specification
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Zebrafish sp7 mutants show tooth cycling independent of attachment, eruption and poor differentiation of teeth
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Update on the pathophysiology and risk factors for the development of malignant testicular germ cell tumors in complete androgen insensitivity syndrome
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- Journal Article
- A1
- open access
PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence
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- Journal Article
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Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote
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TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models
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PHR1 balances between nutrition and immunity in plants
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- Journal Article
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Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis
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Live-cell analysis of DNA methylation during sexual reproduction in Arabidopsis reveals context and sex-specific dynamics controlled by noncanonical RdDM
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A vertebrate-specific and essential role for osterix in osteogenesis revealed by gene knockout in the teleost medaka
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Toxicity, membrane binding and uptake of the Sclerotinia sclerotiorum agglutinin (SSA) in different insect cell lines
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In search of lost small peptides
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- Journal Article
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Ectopic application of the repressive histone modification H3K9me2 establishes post-zygotic reproductive isolation in Arabidopsis thaliana
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- Journal Article
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THADA regulates the organismal balance between energy storage and heat production
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- Journal Article
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Revisiting in vivo staining with alizarin red S - a valuable approach to analyse zebrafish skeletal mineralization during development and regeneration
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Functions and regulation of programmed cell death in plant development
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- Journal Article
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RBOH-mediated ROS production facilitates lateral root emergence in Arabidopsis
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Slow cycling cells in the continuous dental lamina of Scyliorhinus canicula : new evidence for stem cells in sharks
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- Journal Article
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Early development of the root-knot nematode Meloidogyne incognita
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RNAi in insects: use of insect cell cultures to better understand and increase efficacy
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IAPs, regulators of innate immunity and inflammation
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Plant embryogenesis requires AUX/LAX-mediated auxin influx
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Mineral homeostasis and regulation of mineralization processes in the skeletons of sharks, rays and relatives (Elasmobranchii)
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- Journal Article
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Development of the stria vascularis and potassium regulation in the human fetal cochlea : insights into hereditary sensorineural hearing loss
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- Journal Article
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Development of the follicular basement membrane during human gametogenesis and early folliculogenesis
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An alkaline follicular fluid fraction induces capacitation and limited release of oviduct epithelium-bound stallion sperm
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- Journal Article
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- open access
The cyclophilin A DIAGEOTROPICA gene affects auxin transport in both root and shoot to control lateral root formation
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A bHLH-based feedback loop restricts vascular cell proliferation in plants
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Investigating CNS synaptogenesis at single-synapse resolution by combining reverse genetics with correlative light and electron microscopy
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- Journal Article
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Cell type-specific transcriptome analysis in the early Arabidopsis thaliana embryo
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- Journal Article
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Comparative developmental osteology of the seahorse skeleton reveals heterochrony amongst Hippocampus sp. and progressive caudal fin loss
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Germline quality control: eEF2K stands guard to eliminate defective oocytes
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Necroptosis, in vivo detection in experimental disease models
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- Journal Article
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Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development
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Toxic effects of Hoechst staining and UV irradiation on preimplantation development of parthenogenetically activated mouse oocytes
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Traffic control in the root: keeping root branching in check
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Caspase-7 participates in differentiation of cells forming dental hard tissues
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Variable loss of functional activities of androgen receptor mutants in patients with androgen insensitivity syndrome
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A bHLH complex controls embryonic vascular tissue establishment and indeterminate growth in Arabidopsis
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- Journal Article
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The Wnt signaling mediator tcf1 is required for expression of foxd3 during Xenopus gastrulation
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Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors
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To branch or not to branch: the role of pre-patterning in lateral root formation
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Higher plant transformation: principles and molecular tools
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From the tumor-inducing principle to plant biotechnology and its importance for society
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Thirty years of transgenic research in plants
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Transgenic plants: from first successes to future applications
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Role of plant expression systems in antibody production for passive immunization
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Plant transgenesis
Maria Van Lijsebettens (UGent) and Geert Angenon(2013) 57 (6-8). -
Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process
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GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses
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A transgenic mouse marking live replicating cells reveals in vivo transcriptional program of proliferation
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Plant developmental biologists meet on stairways in Matera
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Genetic framework of cyclin-dependent kinase function in Arabidopsis
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An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue
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Conditional ablation of osteoblasts in medaka
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Vestiges, rudiments and fusion events: the zebrafish caudal fin endoskeleton in an evo-devo perspective
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Rankl-induced osteoclastogenesis leads to loss of mineralization in a medaka osteoporosis model
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Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation
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Evolution of self-organisation in Dictyostelia by adaptation of a non-selective phosphodiesterase and a matrix component for regulated cAMP degradation
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Distinct patterns of notochord mineralization in zebrafish coincide with the localization of Osteocalcin isoform 1 during early vertebral centra formation
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Inflammasomes and their roles in health and disease
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Hormonal interactions in the regulation of plant development
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The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells
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Developmental and cancer research on the mammary gland nowadays: preface
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Signaling networks in cancer: an interview with Christian Gespach
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From the laboratory to the patient and back: an interview with Marc Mareel
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Exosome signaling in mammary gland development and cancer
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- Journal Article
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- open access
Brassinosteroids control meristem size by promoting cell cycle progression in Arabidopsis roots
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Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers
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Gonadal development and tumor formation at the crossroads of male and female sex determination
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Partial deletion of the NR5A1 (SF1) gene, detected by synthetic probe MLPA, in a patient with XY gonadal disorder of sex development
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Boule-like genes regulate male and female gametogenesis in the flatworm Macrostomum lignano
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Inositol trisphosphate-induced Ca2+ signaling modulates auxin transport and PIN polarity
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Multi-probe in situ hybridization to whole mount Arabidopsis seedlings
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Cytokinin modulates endocytic trafficking of PIN1 auxin efflux carrier to control plant organogenesis
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Role of PIN-mediated auxin efflux in apical hook development of Arabidopsis thaliana
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The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development in Arabidopsis thaliana seedlings
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A conditional mutation in Arabidopsis thaliana separase induces chromosome non-disjunction, aberrant morphogenesis and cyclin B1;1 stability
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Oscillatory Ca2+ dynamics and cell cycle resumption at fertilization in mammals: a modelling approach
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Nitrate contra auxin: nutrient sensing by roots
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Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression
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The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo
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Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants
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Plasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling
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Direct control of Hoxd1 and Irx3 expression by Wnt/β-catenin signaling during anteroposterior patterning of the neural axis in Xenopus
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Inferring the ancestral function of the posterior Hox gene within the bilateria: controlling the maintenance of reproductive structures, the musculature and the nervous system in the acoel flatworm Isodiametra pulchra
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Tumor risk in disorders of sex development
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- Journal Article
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- open access
Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignano
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- Journal Article
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- open access
The caudal regeneration blastema is an accumulation of rapidly proliferating stem cells in the flatworm Macrostomum lignano
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- Journal Article
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Characterization of the stem cell system of the acoel Isodiametra pulchra
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Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms
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Requirement of Wnt/beta-catenin signaling in pronephric kidney development
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Impaired neural crest migration contributes to midgestation lethality of beta-actin knock-out mouse
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BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration
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Auxin transport routes in plant development
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- Journal Article
- A1
- open access
Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants
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- Journal Article
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Quantification of Fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine preimplantation embryos
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An evolutionary view on tooth development and replacement in wild Atlantic salmon (Salmo salar L.)
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Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects
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Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development
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The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability
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Flatworm stem cells and the germ line: developmental and evolutionary implications of Macvasa expression in Macrostomum lignano
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Polar targeting and endocytic recycling in auxin-dependent plant development
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The adolescent brain: insights from functional neuroimaging
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CTG repeat instability in a human embryonic stem cell line carrying the myotonic dystrophy type 1 mutation
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The embryonic cell lineage of the nematode Rhabditophanes sp.
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Effect of 17 beta-estradiol on the in vitro differentiation of murine embryonic stem cells into the osteogenic lineage
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Cell-free expression and functionality analysis of the tobacco lectin
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Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling
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Auxin-dependent regulation of lateral root positioning in the basal meristem of Arabidopsis
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- Journal Article
- A1
- open access
Novel subdomains of the mouse olfactory bulb defined by molecular heterogeneity in the nascent external plexiform and glomerular layers
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The zebrafish laf/alk8 mutant as an in vivo model for molecular dissection of replacement tooth formation
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Plant defense systems mediated by protein-carbohydrate recognition.
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In vitro evaluation of antihypertensive mechanism of the dipeptide Val-Tyr in rat aorta organ bath experiments
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Identification and expression analysis of genes associated with bovine blastocyst formation
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- Journal Article
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Cell elongation is key to in silico replication of in vitro vasculogenesis and subsequent remodeling
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- Journal Article
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Formation of a successional dental lamina in the zebrafish (Danio rerio): support for a local control of replacement tooth initiation
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Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation
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Functional redundancy of PIN proteins is accompanied by auxindependent cross-regulation of PIN expression
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Historical perspectives on plant developmental biology
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Selection of reference genes for quantitative real-time PCR in bovine preimplantation embryos
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Canonical Wnt signaling is required for pronephric kidney tubule development.
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Kaiso/p120-catenin and TCF/Beta-Catenin complexes coordinately regulate canonical wnt gene targets.
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Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis
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- Journal Article
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Constant and continuous growth reduction as a possible cause of ageing
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Cre recombinase specificity defined by the tau locus
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The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413
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Germinal tumor invasion and the role of the testicular stroma
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N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling
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Molecular cell biology and cancer metastasis - An interview with Garth Nicolson
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Telomere biology in mammalian germ cells and during development
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- open access
Evolution of neural precursor selection: functional divergence of proneural proteins
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The identification of the phylotyic stage in nematode embryos
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Contrasting activities of the aggregative and late PDSA promoters in Dictyostelium development
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Impaired intervertebral disc formation in the absence of Jun
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Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling
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The p120 catenin regulates morphogenetic movements in early xenopus embryos by modifying the activity of the rho-family small Gtpases.
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Embryonic cell lineage of the marine nematode Pellioditis marina
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Hepatic progenitor cells in human liver diseases
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Differentiation and growth of kype skeletal tissues in anadromous male Atlantic Salmon (Salmo salar)
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Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin.
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Developmental potential of cloned mouse embryos reconstructed by a conventional technique of nuclear injection.
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unc-53 controls longitudinal migration in C-elegans.
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Mouse mammary gland involution is associated with cytochrome c release and caspase activation.