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The environmental impact of laboratory measurements in high-resource ICUs
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Environmental sustainability and antimicrobials : an underestimated problem with far-reaching consequences
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Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients : the EUROBACT-2 international cohort study
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Selective digestive decontamination-Pro
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Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA) : an international prospective multicenter cohort study
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- Miscellaneous
- open access
Towards adequate and automated antibiotic dosing
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Advancing precision-based antimicrobial dosing in critically ill patients
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Aerosolised antibiotics in critical care
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Source control in the management of sepsis and septic shock
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Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19
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- Journal Article
- A1
- open access
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study
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- Journal Article
- A1
- open access
The AKI care bundle : all bundle components are created equal-are they?
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Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease : a secondary analysis of the STARRT-AKI trial
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- Miscellaneous
- open access
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study (vol 48, pg 690, 2022)
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- Journal Article
- A1
- open access
De-adoption of chlorhexidine oral care and ICU mortality
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- Journal Article
- A1
- open access
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
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- Miscellaneous
- open access
Preventing pressure injuries among patients in the intensive care unit : insights gained
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Critically ill cancer patient’s resuscitation : a Belgian/French societies’ consensus conference
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Surviving sepsis campaign : international guidelines for management of sepsis and septic shock 2021
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Antimicrobial stewardship in ICUs during the COVID-19 pandemic : back to the 90s?
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Antiseptic mouthwash, the nitrate–nitrite–nitric oxide pathway, and hospital mortality : a hypothesis generating review
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Posaconazole for prevention of invasive pulmonary aspergillosis in critically ill influenza patients (POSA-FLU) : a randomised, open-label, proof-of-concept trial
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- Journal Article
- A1
- open access
Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis
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- Journal Article
- A1
- open access
Acute kidney injury in the critically ill : an updated review on pathophysiology and management
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- Journal Article
- A1
- open access
Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI) : a pilot randomized controlled feasibility trial
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The future of antimicrobial dosing in the ICU : an opportunity for data science
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- Journal Article
- A1
- open access
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients : the DecubICUs study
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Less daily oral hygiene is more in the ICU : not sure
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- Journal Article
- A1
- open access
Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition : an expert opinion
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Antimicrobial de-escalation in critically ill patients : a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)
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Conventional amphotericin B must be avoided in Candida infections
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The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs : the VIP2 study
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- Journal Article
- A1
- open access
Lung-kidney interactions in critically ill patients : consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup
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- Journal Article
- A1
- open access
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study
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Antimicrobial therapeutic drug monitoring in critically ill adult patients : a Position Paper#
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- Journal Article
- A1
- open access
Ethical climate and intention to leave among critical care clinicians : an observational study in 68 intensive care units across Europe and the United States
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A microbiologist consultant should attend daily ICU rounds
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‘Less is more’ in modern ICU : blessings and traps of treatment limitation
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Focus on metabolism, acute kidney injury and its influence on systemic organs
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Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care : no simple answers to simple questions - a viewpoint of experts
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Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura (vol 45, pg 1518, 2019)
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- Journal Article
- A1
- open access
Identification and validation of biomarkers of persistent acute kidney injury : the RUBY study
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Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria : understanding nebulization of aminoglycosides and colistin
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- Journal Article
- A1
- open access
International critical care nursing considerations and quality indicators for the 2017 surviving sepsis campaign guidelines
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Catheter-associated bloodstream infection rates : how low can you go?
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Focus on ethics of admission and discharge policies and conflicts of interest
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Changes in critically ill cancer patients’ short-term outcome over the last decades : results of systematic review with meta-analysis on individual data
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Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura
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Focus on ethics and palliative care in the intensive care unit
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ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients
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Persistence of piperacillin concentrations after treatment discontinuation : in cauda venenum?
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Intensive care medicine in 2050 : preventing harm
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Determinants of downloads and citations for articles published in Intensive Care Medicine
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- Journal Article
- A1
- open access
Epidemiology of intra-abdominal infection and sepsis in critically ill patients : 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project
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Rationalizing antimicrobial therapy in the ICU : a narrative review
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Personalized antibiotic dosing for the critically ill
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Research priorities in pediatric onco-critical care : an international Delphi consensus study
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Less is more : ten reasons for considering to discontinue unproven interventions
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Angiotensin inhibition in patients with acute kidney injury : Dr. Jekyll or Mr. Hyde?
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Antimicrobial resistance and antibiotic stewardship programs in the ICU : insistence and persistence in the fight against resistance : a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance
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- Journal Article
- A1
- open access
Effects of chlorhexidine gluconate oral care on hospital mortality : a hospital-wide, observational cohort study
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- Journal Article
- A1
- open access
Outcome in patients perceived as receiving excessive care across different ethical climates : a prospective study in 68 intensive care units in Europe and the USA
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Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients : the multinational AID-ICU inception cohort study
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Predicting outcomes in very old ICU patients : time to focus on the past?
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Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit
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Beat around the bush for VA-LRTI
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Pain distress : the negative emotion associated with procedures in ICU patients
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Competing and conflicting interests in the care of critically ill patients
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- Journal Article
- A1
- open access
Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
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Life after death in the ICU : detecting family-centered outcomes remains difficult
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Focus on palliative care in the ICU
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- Journal Article
- A1
- open access
Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017
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Diagnostic work-up and specific causes of acute kidney injury
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The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)
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The status of intensive care medicine research and a future agenda for very old patients in the ICU
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Critical care admission following elective surgery was not associated with survival benefit : prospective analysis of data from 27 countries
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Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury
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Understanding oliguria in the critically ill
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The intensive care medicine agenda on acute kidney injury
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- Journal Article
- A1
- open access
Early enteral nutrition in critically ill patients : ESICM clinical practice guidelines
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The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections
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The Intensive Care Medicine research agenda on critically ill oncology and hematology patients
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Have renal biomarkers failed in acute kidney injury? Yes
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Did KDIGO guidelines on acute kidney injury improve patient outcome?
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Evidence in the eye of the beholder : about probiotics and VAP prevention
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Therapeutic management of peritonitis : a comprehensive guide for intensivists
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Understanding antibiotic stewardship for the critically ill
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Understanding abdominal compartment syndrome
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Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study
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Focus on adequate antimicrobial treatment and de-escalation in the ICU
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Antibiotic stewardship : do not rely on de-escalation alone
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- Journal Article
- A1
- open access
Oral mucosal adverse events with chlorhexidine 2 % mouthwash in ICU
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Focus on immunocompromised patients
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Prone position acute respiratory distress syndrome patients : less prone to ventilator associated pneumonia?
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Does increased ICU strain prompt clinicians to communicate with families about end-of-life issues earlier?
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Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria
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Year in review in Intensive Care Medicine 2014, I: cardiac dysfunction and cardiac arrest, ultrasound, neurocritical care, ICU-acquired weakness, nutrition, acute kidney injury, and miscellaneous
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The ten 'diseases' that are not true diseases
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- Journal Article
- A1
- open access
Fluid challenges in intensive care : the FENICE study A global inception cohort study
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- Journal Article
- A1
- open access
The state of critical care nursing education in Europe: an international survey
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Comparison of different equations to assess glomerular filtration in critically ill patients
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Year in review in Intensive Care Medicine 2014, III: severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics
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Year in review in Intensive Care Medicine 2014, II: ARDS, airway management, ventilation, adjuvants in sepsis, hepatic failure, symptoms assessment and management, palliative care and support for families, prognostication, organ donation, outcome, organisation and research methodology
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Prognosis of neutropenic patients admitted to the intensive care unit
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Task force on management and prevention of Acinetobacter baumannii infections in the ICU
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Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
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Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
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Acute respiratory distress syndrome in patients with malignancies
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Year in review in Intensive Care Medicine 2013, III: sepsis, infections, respiratory diseases, pediatrics
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Year in review in Intensive Care Medicine 2013, II: sedation, invasive and noninvasive ventilation, airways, ARDS, ECMO, family satisfaction, end-of-life care, organ donation, informed consent, safety, hematological issues in critically ill patients
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Year in review in Intensive Care Medicine 2013, I: acute kidney injury, ultrasound, hemodynamics, cardiac arrest, transfusion, neurocritical care, and nutrition
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What's new in the controversy on the renal/tissue toxicity of starch solutions?
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Clinical practice guideline on diagnosis and treatment of hyponatraemia
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Impact of de-escalation on ICU patients' prognosis
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Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients
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What is new in the use of aminoglycosides in critically ill patients?
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What's new in invasive pulmonary aspergillosis in the critically ill?
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What is new in infection prevention in critical care in 2014?
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Long-term outcome and quality of life in ICU patients with acute kidney injury treated with renal replacement therapy: a case control study
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Clinical predictors of neonatal healthcare-associated bloodstream infections: a systematic review and meta-analysis
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Predicting postoperative acute kidney injury in a cardiac surgery population: external validation of existing scoring systems and possible benefit of implementation of the biomarker CHI3L1
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Empiric anti-pseudomonas antibiotic therapy in complicated intra-abdominal infections: a systematic review and meta-analysis
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Risk factors for mortality in elderly patients (>75 years old) with invasive aspergillosis
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Impact of neonatal healthcare-associated bloodstream infections on mortality in a neonatal intensive care unit
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Risk factors for neonatal healthcare-associated bloodstream infections in a neonatal intensive care unit
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- Journal Article
- A1
- open access
Intra-abdominal hypertension and the abdominal compartment syndrome : updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome
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Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia : systematic review and diagnostic test accuracy meta-analysis
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Long-term outcomes and quality of life in critically ill patients with hematological or solid malignancies: a single center study
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Thrombocytopenia in the critically ill: considering pathophysiology rather than looking for a magic threshold
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An urgent plea: give the use of prolonged propofol infusion a second thought
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- Journal Article
- A1
- open access
Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome : a prospective multicentre study
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Reporting and handling missing values in clinical studies in intensive care units
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Aspergillosis in critically ill patients: results from a large multicenter cohort
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Characeteristics and outcome of neonates with a healthcare-associated bloodstream infection in a NICU over a 10-year period (2002-2011)
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- Journal Article
- A1
- open access
Gastrointestinal function in intensive care patients : terminology, definitions and management: recommendations of the ESICM Working Group on Abdominal Problems
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Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT international cohort study
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Comments on Reinhart et al.: consensus statement of the ESICM task force on colloid volume therapy in critically ill patients
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Epidemiology of contrast-associated acute kidney injury in ICU patients: reply to Valette and du Cheyron
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Side effects of hydroxyethyl starch formulations: probably not so equal at all
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TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial
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- Journal Article
- A1
- open access
Measuring the nursing workload per shift in the ICU
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Beliefs, attitudes and practices of oral care : a comparison between European and Iranian intensive care nurses
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Oral health care in intubated patients: exploration of knowledge and practice among 663 ICU nurses
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Influence of patient position on endotracheal tube cuff pressure: results of a pilot study in mechanically ventilated patients
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Does femoral venous pressure measurement correlate well with intrabladder pressure measurement?: a multicenter observational trial
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Epidemiology of contrast-associated acute kidney injury in ICU patients: a retrospective cohort analysis
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The epidemiologicy of acute kidney injury: preliminary results of the multicenter international AKI-EPI study
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International expert statement on training standards for critical care ultrasonography
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Value of respiratory tract surveillance cultures to predict microbial etiology in ventilator-associated pneumonia : a diagnostic test accuracy meta-analysis
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Open lung biopsy in patients with acute respiratory failure and bilateral pulmonary infiltrates
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Outcome of acute kidney injury in severe burns : a systematic review and meta-analysis
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A note on statistical association and causality derived from epidemiological ICU data: reply
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- Conference Paper
- C3
- open access
Clinical relevance of aspergillus positive endotracheal aspirate cultures in critically ill patients : validation of an algorithm to discriminate aspergillus colonization from invasive pulmonary aspergillosis
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- Conference Paper
- C3
- open access
Incidence of ventilator-associated pneumonia in burn patients with inhalation injury and the value of routine endotracheal aspirate surveillance cultures to predict involvement of multidrug resistant microbial etiology
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- Conference Paper
- C3
- open access
Invasive aspergillosis in intensive care units : underlying conditions, clinical presentation, medical imaging, and mortality
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Impact of organ dysfunction on mortality in ICU patients with hematologic malignancies
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Non-invasive ventilation in patients with hematological malignancies: the saga continues, but where is the finale?
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- Conference Paper
- C3
- open access
Preliminary results from the APPROPRICUS study (APPROPRIATENESS of CARE in the ICUs)
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Assessment of increased glomerular filtration rate in ICU patients
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How well do icu nurses know the anatomy and physiology of the respiratory tract?
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Impact of knowledge of rifle status on therapy for aki and aki progression
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Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough
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Comment on "Health-related quality of life as a prognostic factor of survival in critically ill patients"
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Reduction of ventilator-associated pneumonia: enhancing knowledge is important
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What is normal intra-abdominal pressure and how is it affected by positioning, body mass and positive end-expiratory pressure?
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Has information technology finally been adopted in intensive care units?
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EVOLUTION IN COAGULATION PARAMETERS OVER THE FIRST 3 DAYS OF ICU ADMISSION IN SEPTIC SHOCK PATIENTS: IMPACT ON 30 DAY MORTALITY
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EXCESS RISK OF DEATH FROM VENTILATOR ASSOCIATED PNEUMONIA: A REAPPRAISAL USING LONGITUDINAL CAUSAL ANALYSIS
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BACTERIEMIA IN PATIENTS WITH VENTILATOR ASSOCIATED PNEUMONIA: RESULTS FROM EU-VAP STUDY
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ADVERSE EFFECTS OF VOLUME THERAPY WITH HES SOLUTIONS ON KIDNEY FUNCTION: META-ANALYSIS OF PROSPECTIVE, RANDOMIZED CONTROLLED TRIALS
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ADMINISTRATION OF VANCOMYCIN USING A STANDARDIZED PROTOCOL: DO WE ACHIEVE THERAPEUTIC SERUM CONCENTRATION IN THE INITIAL PHASE IN CRITICALLY ILL PATIENTS?
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Total atrioventricular block in burn unit patients: a matter of iodine toxicity
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Intensive care nurses' knowledge and management of tracheal tube cuffs
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Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies
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Transvesical intra-abdominal pressure measurement using minimal instillation volumes: how low can we go?
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In vitro validation of a novel methodfor continuous intra-abdominalpressure monitoring
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Systematic surveillance cultures as a tool to predict involvement of multidrug antibiotic resistant bacteria in ventilator-associated pneumonia
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Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with haematological malignancies: reply to letter by Meyer et al.
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Epoprostenol treatment of acute pulmonary hypertension is associated with a paradoxical decrease in right ventricular contractility
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- Journal Article
- A1
- open access
One single dose of etomidate negatively influences adrenocortical performance for at least 24 h in children with meningococcal sepsis
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The effect of different reference transducer positions on intra-abdominal pressure measurement: a multicenter analysis
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Maximizing rates of empiric appropriate antibiotic therapy with minimized use of broad-spectrum agents: are surveillance cultures the key?
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Temocillin: a valid option for directed therapy in ICU patients?
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Burnout in the ICU: Potential consequences for staff and patient well-being
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Candidemia in the Critical Ill: An economic analysis of daily antimicrobial therapy-related costs
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Results from the International Conference of Experts on Intra-Abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations
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Evidence-based guidelines for the prevention of ventilator-associated pneumonia: results of a knowledge test among intensive care nurses
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Invasive devices: no need? No use!
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Relative adrenal insufficiency in patients with severe acute pancreatitis
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The effect of neuromuscular blockers in patients with intra-abdominal hypertension
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Oral care practices in critical care unit
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Oral care practices in intensive care units: a survey of 59 European ICUs
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- Journal Article
- A1
- open access
Infusions of rocuronium and cisatracurium exert different effects on rat diaphragm function
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- Journal Article
- A1
- open access
Semicontinuous intra-abdominal pressure measurement using an intragastric Compliance catheter
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Outcome in bacteremia associated with nosocomial pneumonia and the impact of pathogen prediction by tracheal surveillance cultures
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Outcome in severely ill patients with hematological malignancies who received intravenous chemotherapy in the intensive care unit
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Saline volume in transvesical intra-abdominal pressure measurement: enough is enough
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Abdominal compartment syndrome: it's time to pay attention!
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Results from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. I. Definitions
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The use of drugs with a life-shortening effect in end-of-life care in neonates and infants
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Outcome and changes over time in survival following severe burns from 1985 to 2004
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Fluid vs. air for semicontinuous intra-abdominal pressure measurements using a compliance catheter
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Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome
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The assumed problem of air bubbles in the tubing during intra-abdominal pressure measurement
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High infection rates in patients with severe acute necrotizing pancreatitis
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Impact of the duration of hyperthermia on cerebral haemodynamics
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Impact of bloodstream infection on the outcome of patients with acute renal failure
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The use of the activated clotting time for monitoring heparin therapy in critically ill patients
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A role for muscle relaxation in patients with abdominal compartment syndrome?
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The impact of timing of surgical intervention on survival in patients with severe acute pancreatitis
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Evaluation of the MARS (R) liver support system in patients with severe liver dysfunction
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Incidence, risk factors and mortality of VAP in the ICU
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Invasive aspergillosis in ICU patients: Analysis for risk factors and mortality
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The use of the activated clotting time for monitoring heparin therapy in critically ill patients (vol 29, pg 325, 2003)
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Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study
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Accuracy and repeatability of pediatric cardiac output measurement using Doppler: 20-year review of the literature
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Factors influencing cardiac troponin I in septic patients with myocardial dysfunction
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Detection of brain injury in patients with septic shock
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Outcome in critically ill hematologic cancer patients : impact of bacterial infection
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Sepsis and acute renal failure: incidence, outcome, and prognostic factors.
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Efficacy and side effects of a single dose of trometamol or bicarbonate as a buffer in patients with mild acidosis
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Attributable mortality of invasive aspergillosis (IA) in critically ill patients
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Antithrombin III in patients with severe sepsis: a pharmacokinetic stury.
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Markers of tissue hypoperfusion in pediatric septic shock.
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Can inflammatory cytokines be removed efficiently by continuous renal replacement therapies?
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Use of continuous bispectral EEG monitoring to assess depth of sedation in ICU patients.
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Pressure measurement evaluation and accuracy validation: the Gabarith test.
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Effects of nebulized salbutamol in ARDS.
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Cerebral perfusion pressure and intracranial pressure in relation to neuropsychological outcome.
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Candida infection in surgical patients.
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Left ventricular systolic and diastolic function in septic shock.
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Gitaloxin poisoning in a child
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Diagnosis of intravascular device related sepsis by a continuous monitoring blood culture system.
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Further prospective evidence of a circadian variation in the frequency of call for sudden cardiac death.
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FAT-EMBOLISM IN A PATIENT WITH RHABDOMYOLYSIS - A RARE CAUSE OF ARDS.
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Early prediction of non-survival for patients suffering cardiac arrest : a word of caution
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Critical review of complications of 137 central venous indwelling catheters in 120 children
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Use of high-frequency ventilation (HFV) in persistance of pulmonary hypertension in the newborn (PPHN)