Ghent University Academic Bibliography

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Your filters: cql: author exact F98B2FB6-F0ED-11E1-A9DE-61C894A0A6B4

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Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

Wim Ceelen (UGent) , Helena Braet (UGent) , Gabrielle Van Ramshorst, Wouter Willaert (UGent) and Katrien Remaut (UGent)

(2020) EXPERT OPINION ON DRUG DELIVERY. 17(4). p.511-522
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Materials and technologies to combat counterfeiting of pharmaceuticals : current and future problem tackling

Heyang Zhang (UGent) , Dawei Hua (UGent) , Chaobo Huang, Sangram Keshari Samal, Ranhua Xiong (UGent) , Félix Sauvage (UGent) , Kevin Braeckmans (UGent) , Katrien Remaut (UGent) and Stefaan De Smedt (UGent)

(2020) ADVANCED MATERIALS. 32(11).
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Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

Thijs Van de Vyver (UGent) , Bram Bogaert (UGent) , Lynn De Backer (UGent) , Freya Joris (UGent) , Roberta Guagliardo (UGent) , Jelter Van Hoeck (UGent) , Pieterjan Merckx (UGent) , Serge Van Calenbergh (UGent) , Srinivas Ramishetti, Dan Peer, et al.

(2020) ACS NANO. 14(4). p.4774-4791
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- Conference Paper
- C3
Electrostatic precipitation is a valuable adjunct to pressurized intraperitoneal aerosol chemotherapy : an in vitro study

Leen Van de Sande (UGent) , Melanie Coetsier, Azarie Victor, Sarah Cosyns (UGent) , Wouter Willaert (UGent) , Molood Shariati (UGent) , Helena Braet (UGent) , Katrien Remaut (UGent) and Wim Ceelen (UGent)

(2020) EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 46. p.e165-e165
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Local release of siRNA using polyplex-loaded thermosensitive hydrogels

Lies A. L. Fliervoet, Heyang Zhang (UGent) , Emma van Groesen, Kyra Fortuin, Naut J. C. B. Duin, Katrien Remaut (UGent) , Raymond M. Schiffelers, Wim E. Hennink and Tina Vermonden

(2020) NANOSCALE. 12(18). p.10347-10360
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Electrostatic intraperitoneal aerosol delivery of nanoparticles : proof of concept and preclinical validation

Leen Van de Sande (UGent) , Mohammad Rahimi Gorji (UGent) , Silvia Giordano, Enrico Davoli, Cristina Matteo, Sonke Detlefsen, Katharina D'Herde (UGent) , Helena Braet (UGent) , Molood Shariati (UGent) , Katrien Remaut (UGent) , et al.

(2020) ADVANCED HEALTHCARE MATERIALS. 9(16).
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Intraperitoneal aerosolized drug delivery : technology, recent developments, and future outlook

Mohammad Rahimi Gorji (UGent) , Leen Van de Sande (UGent) , Charlotte Debbaut (UGent) , G Ghorbaniasl, Helena Braet (UGent) , Sarah Cosyns (UGent) , Katrien Remaut (UGent) , Wouter Willaert (UGent) and Wim Ceelen (UGent)

(2020) ADVANCED DRUG DELIVERY REVIEWS. 160. p.105-114
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Influence of pathogenic stimuli on Müller cell transfection by lipoplexes

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , Frederik Philips (UGent) , Fauve Vergauwe, Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2020) EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 150. p.87-95
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- A2
Fluorescence-based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts

Heyang Zhang (UGent) , Koen Rombouts (UGent) , Laurens Raes (UGent) , Ranhua Xiong (UGent) , Stefaan De Smedt (UGent) , Kevin Braeckmans (UGent) and Katrien Remaut (UGent)

(2020) ADVANCED BIOSYSTEMS. 4(5).
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Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine : cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate peritoneal metastasis of advanced human ovarian cancer

Molood Shariati (UGent) , Giovanna Lollo, Kevin Matha, Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Leen Van de Sande (UGent) , Wouter Willaert (UGent) , Lieve Balcaen (UGent) , Frank Vanhaecke (UGent) , Jean-Pierre Benoit, et al.

(2020) ACS APPLIED MATERIALS & INTERFACES. 12(26). p.29024-29036
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High pressure nebulization (PIPAC) versus injection for the intraperitoneal administration of mRNA complexes

Molood Shariati (UGent) , Heyang Zhang (UGent) , Leen Van de Sande (UGent) , Benedicte Descamps (UGent) , Christian Vanhove (UGent) , Wouter Willaert (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) PHARMACEUTICAL RESEARCH. 36(9).
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Photoablation of human vitreous opacities by light-induced vapor nanobubbles

Félix Sauvage (UGent) , Juan Fraire (UGent) , Katrien Remaut (UGent) , J Sebag, Karen Peynshaert (UGent) , Michael Harrington, Frans J Van de Velde, Ranhua Xiong (UGent) , Marie-Jose Tassignon, Toon Brans (UGent) , et al.

(2019) ACS NANO. 13(7). p.8401-8416
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Non-viral delivery of chemically modified mRNA to the retina : subretinal versus intravitreal administration

Joke Devoldere (UGent) , Karen Peynshaert (UGent) , Heleen Dewitte (UGent) , Christian Vanhove (UGent) , Lies De Groef, Lieve Moons, Sinem Yilmaz Özcan, Deniz Dalkara, Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) JOURNAL OF CONTROLLED RELEASE. 307. p.315-330
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Aerosolization of nanotherapeutics as a newly emerging treatment regimen for peritoneal carcinomatosis

Molood Shariati (UGent) , Wouter Willaert (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) CANCERS. 11(7).
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The obstacle course to the inner retina : hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane

Joke Devoldere (UGent) , Mike Wels (UGent) , Karen Peynshaert (UGent) , Heleen Dewitte (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 141. p.161-171
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Establishment of a rat ovarian peritoneal metastasis model to study pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Leen Van de Sande (UGent) , Wouter Willaert (UGent) , Sarah Cosyns (UGent) , Kaat De Clercq (UGent) , Molood Shariati (UGent) , Katrien Remaut (UGent) and Wim Ceelen (UGent)

(2019) BMC CANCER. 19.
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Morphology and composition of the inner limiting membrane : species-specific variations and relevance toward drug delivery research

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , An-Katrien Minnaert (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) CURRENT EYE RESEARCH. 44(5). p.465-475
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Müller cells as a target for retinal therapy

Joke Devoldere (UGent) , Karen Peynshaert (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2019) DRUG DISCOVERY TODAY. 24(8). p.1483-1498
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Fluorescence correlation spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes

Heyang Zhang (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2018) ACTA BIOMATERIALIA. 75. p.358-370
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Search for the source of the retinal relaxing factor

Laura Vanden Daele (UGent) , Charlotte Boydens (UGent) , Joke Devoldere (UGent) , Katrien Remaut (UGent) and Johan Van de Voorde (UGent)

(2018) CURRENT EYE RESEARCH. 43(11). p.1383-1388
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Towards the development of a RNAi-based topical treatment for psoriasis : proof-of-concept in a 3D psoriasis skin model

Eline Desmet, Mireille Van Gele (UGent) , Lynda Grine (UGent) , Katrien Remaut (UGent) and Jo Lambert (UGent)

(2018) EXPERIMENTAL DERMATOLOGY. 27(5). p.463-469
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Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles

Lotte Vermeulen (UGent) , Toon Brans (UGent) , Sangram Keshari Samal (UGent) , Peter Dubruel (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2018) ACS NANO. 12(3). p.2332-2345
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Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy

Lotte Vermeulen (UGent) , Toon Brans (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2018) NANO TODAY. 21. p.74-90
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The proton sponge hypothesis : fable or fact?

Lotte Vermeulen (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2018) EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 129. p.184-190
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Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles

Lotte Vermeulen (UGent) , Juan Fraire (UGent) , Laurens Raes (UGent) , Ellen De Meester (UGent) , Sarah De Keulenaer (UGent) , Filip Van Nieuwerburgh (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2018) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 19(8).
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Technical implementations of light sheet microscopy

Elisa Zagato (UGent) , Toon Brans (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) , Kristiaan Neyts (UGent) and Kevin Braeckmans (UGent)

(2018) MICROSCOPY RESEARCH AND TECHNIQUE. 81(9). p.941-958
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Quantifying the average number of nucleic acid therapeutics per nanocarrier by single particle tracking microscopy

Elisa Zagato (UGent) , Lotte Vermeulen (UGent) , Heleen Dewitte (UGent) , Griet Van Imschoot (UGent) , Roosmarijn Vandenbroucke (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Kristiaan Neyts (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2018) MOLECULAR PHARMACEUTICS. 15(3). p.1142-1149
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In vitro and ex vivo models to study drug delivery barriers in the posterior segment of the eye

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2018) ADVANCED DRUG DELIVERY REVIEWS. 126. p.44-57
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Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo Lou, Ans De Beuckelaer (UGent) , George Dakwar (UGent) , Katrien Remaut (UGent) , Johan Grooten (UGent) , Kevin Braeckmans (UGent) , Bruno De Geest (UGent) , Enrico Mastrobattista, Stefaan De Koker (UGent) and Wim E. Hennink

(2018) JOURNAL OF CONTROLLED RELEASE. 284. p.73-83
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Microfabricated devices for single objective single plane illumination microscopy (SoSPIM)

Elisa Zagato (UGent) , Toon Brans (UGent) , Steven Verstuyft (UGent) , Dries Van Thourhout (UGent) , Jeroen Missinne (UGent) , Geert Van Steenberge (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) , Kristiaan Neyts (UGent) , et al.

(2017) OPTICS EXPRESS. 25(3). p.1732-1745
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Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid

George Dakwar (UGent) , Kevin Braeckmans (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2017) DRUG DELIVERY AND TRANSLATIONAL RESEARCH. 7(2). p.241-251
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Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis : mission possible?

George Dakwar (UGent) , Molood Shariati (UGent) , Wouter Willaert (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2017) ADVANCED DRUG DELIVERY REVIEWS. 108. p.13-24
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Coating of quantum dots strongly defines their effect on lysosomal health and autophagy

Karen Peynshaert (UGent) , Stefaan J Soenen, Bella B Manshian, Shareen H Doak, Kevin Braeckmans (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2017) ACTA BIOMATERIALIA. 48. p.195-205
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PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy

Antoine Frère, Alexandra Baroni, Elodie Hendrick, Anne-Sophie Delvigne, François Orange, Olivier Peulen, George Dakwar (UGent) , Jérôme Diricq, Philippe Dubois, Brigitte Evrard, et al.

(2017) ACS APPLIED MATERIALS & INTERFACES. 9(3). p.2181-2195
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Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy

Thomas Martens (UGent) , Karen Peynshaert (UGent) , Thaís Leite Nascimento, Elias Fattal, Marcus Karlstetter, Thomas Langmann, Serge Picaud, Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) , et al.

(2017) EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 103. p.27-35
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High-pressure nebulization as application route for the peritoneal administration of siRNA complexes

An-Katrien Minnaert (UGent) , George Dakwar (UGent) , Juan M Benito, José M García Fernández, Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2017) MACROMOLECULAR BIOSCIENCE. 17(10).
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Toward smart design of retinal drug carriers : a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface

Karen Peynshaert (UGent) , Joke Devoldere (UGent) , Valérie Forster, Serge Picaud, Christian Vanhove (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2017) DRUG DELIVERY. 24(1). p.1384-1394
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Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies

Koen Rombouts (UGent) , Kevin Braeckmans (UGent) and Katrien Remaut (UGent)

(2016) BIOCONJUGATE CHEMISTRY. 27(2). p.280-297
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Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA

Tania Furst, George Dakwar (UGent) , Elisa Zagato (UGent) , Anna Lechanteur, Katrien Remaut (UGent) , Brigitte Evrard, Kevin Braeckmans (UGent) and Geraldine Piel

(2016) JOURNAL OF CONTROLLED RELEASE. 236. p.68-78
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Approximate Bayesian computation for estimating number concentrations of monodisperse nanoparticles in suspension by optical microscopy

Magnus Röding, Elisa Zagato (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2016) PHYSICAL REVIEW E. 93(6).
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Evading innate immunity in nonviral mRNA delivery : don't shoot the messenger

Joke Devoldere (UGent) , Heleen Dewitte (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2016) DRUG DISCOVERY TODAY. 21(1). p.11-25
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Aerosolized non-viral nucleic acid delivery in the vaginal tract of pigs

Katrien Remaut (UGent) , Evelien De Clercq (UGent) , Oliwia Andries (UGent) , Koen Rombouts (UGent) , Matthias Van Gils (UGent) , Laetitia Cicchelero (UGent) , Ian Vandenbussche (UGent) , Sarah Van Praet, Juan Manuel Benito, José Manuel Garcia Fernandéz, et al.

(2016) PHARMACEUTICAL RESEARCH. 33(2). p.384-394
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Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Thomas Martens (UGent) , Katrien Remaut (UGent) , Hendrik Deschout (UGent) , Johan FJ Engbersen, Wim E Hennink, Mies J van Steenbergen, Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Kevin Braeckmans (UGent)

(2015) JOURNAL OF CONTROLLED RELEASE. 202. p.83-92
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Targeted decationized polyplexes for siRNA delivery

Luis Novo, Kaori M Takeda, Tamara Petteta, George Dakwar (UGent) , Joep B van den Dikkenberg, Katrien Remaut (UGent) , Kevin Braeckmans (UGent) , Cornelus F van Nostrum, Enrico Mastrobattista and Wim E Hennink

(2015) MOLECULAR PHARMACEUTICS. 12(1). p.150-161
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- Book Chapter
Intraperitoneal nonviral nucleic acid delivery in the treatment of peritoneal cancer

George Dakwar (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2015) Intraperitoneal cancer therapy : principles and practice. p.359-371
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Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles

George Dakwar (UGent) , Kevin Braeckmans (UGent) , Jo Demeester (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2015) ACS APPLIED MATERIALS & INTERFACES. 7(43). p.24322-24329
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Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori

Rita Santos (UGent) , George Dakwar (UGent) , Ranhua Xiong (UGent) , Katrien Forier (UGent) , Katrien Remaut (UGent) , Stephan Stremersch (UGent) , Nuno Guimarães, Silvia Fontenete, Jesper Wengel, Marina Leite, et al.

(2015) MOLECULAR THERAPY-NUCLEIC ACIDS. 4.
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Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

Stefano Colombo, Dongmei Cun, Katrien Remaut (UGent) , Matt Bunker, Jianxin Zhang, Birte Martin-Bertelsen, Anan Yaghmur, Kevin Braeckmans (UGent) , Hanne M. Nielsen and Camilla Foged

(2015) JOURNAL OF CONTROLLED RELEASE. 201. p.22-31
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Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery

Elisa Zagato (UGent) , Katrien Forier (UGent) , Thomas Martens (UGent) , Kristiaan Neyts (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Kevin Braeckmans (UGent)

(2014) NANOMEDICINE. 9(6). p.913-927
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Intracellular delivery of nanomaterials: how to catch endosomal escape in the act

Thomas Martens (UGent) , Katrien Remaut (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Kevin Braeckmans (UGent)

(2014) NANO TODAY. 9(3). p.344-364
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Cell division responsive peptides for optimized plasmid DNA delivery : the mitotic window of opportunity?

Katrien Remaut (UGent) , Nathalie Symens (UGent) , Bart Lucas (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 179. p.1-9
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Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery

Katrien Remaut (UGent) , Viola Oorschot, Kevin Braeckmans (UGent) , Judith Klumperman and Stefaan De Smedt (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 195. p.29-36
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Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Luís Novo, Larissa Y Rizzo, Suzanne K Golombek, George Dakwar (UGent) , Bo Lou, Katrien Remaut (UGent) , Enrico Mastrobattista, Cornelus F van Nostrum, Wilhelm Jahnen-Dechent, Fabian Kiessling, et al.

(2014) JOURNAL OF CONTROLLED RELEASE. 195. p.162-175
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Effect of covalent fluorescence labeling of plasmid DNA on its intracellular processing and transfection with lipid-based carriers

Koen Rombouts (UGent) , Thomas Martens (UGent) , Elisa Zagato (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Kevin Braeckmans (UGent) and Katrien Remaut (UGent)

(2014) MOLECULAR PHARMACEUTICS. 11(5). p.1359-1368
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Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy

George Dakwar (UGent) , Elisa Zagato (UGent) , Joris Delanghe (UGent) , Sabina Hobel, Achim Aigner, Hannelore Denys (UGent) , Kevin Braeckmans (UGent) , Wim Ceelen (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2014) ACTA BIOMATERIALIA. 10(7). p.2965-2975
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Noncoding DNA in lipofection of HeLa cells: a few insights

Nathalie Symens (UGent) , Joanna Rejman (UGent) , Bart Lucas (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2013) MOLECULAR PHARMACEUTICS. 10(3). p.1070-1079
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Measuring the intravitreal mobility of nanomedicines with single-particle tracking microscopy

Thomas Martens (UGent) , Dries Vercauteren (UGent) , Katrien Forier (UGent) , Hendrik Deschout (UGent) , Katrien Remaut (UGent) , Rik Paesen, Marcel Ameloot, Johan FJ Engbersen, Jo Demeester (UGent) , Stefaan De Smedt (UGent) , et al.

(2013) NANOMEDICINE. 8(12). p.1955-1968
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Correlation of dual colour single particle trajectories for improved detection and analysis of interactions in living cells

Hendrik Deschout (UGent) , Thomas Martens (UGent) , Dries Vercauteren (UGent) , Katrien Remaut (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) , Kristiaan Neyts (UGent) and Kevin Braeckmans (UGent)

(2013) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 14(8). p.16485-16514
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Efficient transfection of hepatocytes mediated by mRNA complexed to galactosylated cyclodextrins

Nathalie Symens (UGent) , Alejandro Méndez-Ardoy, Alejandro Diaz-Moscoso, Elena Sánchez-Fernéndez, Katrien Remaut (UGent) , Jo Demeester (UGent) , José M García Fernández, Stefaan De Smedt (UGent) and Joanna Rejman (UGent)

(2012) BIOCONJUGATE CHEMISTRY. 23(6). p.1276-1289
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Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis

Nathalie Symens (UGent) , Stefaan Soenen (UGent) , Joanna Rejman (UGent) , Kevin Braeckmans (UGent) , Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2012) ADVANCED DRUG DELIVERY REVIEWS. 64(1). p.78-94
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Matrix systems for siRNA delivery

Broes Naeye, Koen Raemdonck (UGent) , Katrien Remaut (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2012) CURRENT TOPICS IN MEDICINAL CHEMISTRY. 12(2). p.89-96
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- Conference Paper
- C3
An ex vivo assay to measure the mobility inside the eye of nanomedicines for retinal gene therapy

Thomas Martens (UGent) , Dries Vercauteren (UGent) , Katrien Forier (UGent) , Hendrik Deschout (UGent) , Katrien Remaut (UGent) , Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Kevin Braeckmans (UGent)

(2012) HUMAN GENE THERAPY. 23(10). p.A81-A82
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Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles

Nathalie Symens (UGent) , Rudolf Walczak, Jo Demeester (UGent) , Iain Mattaj, Stefaan De Smedt (UGent) and Katrien Remaut (UGent)

(2011) MOLECULAR PHARMACEUTICS. 8(5). p.1757-1766
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- A1
Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

Dries Vercauteren (UGent) , Hendrik Deschout (UGent) , Katrien Remaut (UGent) , Johan FJ Engbersen, Arwyn T Jones, Jo Demeester (UGent) , Stefaan De Smedt (UGent) and Kevin Braeckmans (UGent)

(2011) ACS NANO. 5(10). p.7874-7884
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- Journal Article
- A1
Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles

Kevin Braeckmans (UGent) , Kevin Buyens (UGent) , Broes Naeye, Dries Vercauteren (UGent) , Hendrik Deschout (UGent) , Koen Raemdonck (UGent) , Katrien Remaut (UGent) , Niek Sanders (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2010) JOURNAL OF CONTROLLED RELEASE. 148(1). p.69-74
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- Journal Article
- A1
- open access
PEGylation of biodegradable dextran nanogels for siRNA delivery

Broes Naeye, Koen Raemdonck (UGent) , Katrien Remaut (UGent) , B Sproat, Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2010) EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 40(4). p.342-351
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- A1
- open access
Efficient delivery of intact phosphodiester oligonucleotides by poly-β-amino esters

Katrien Remaut (UGent) , Nathalie Symens (UGent) , Bart Lucas (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2010) JOURNAL OF CONTROLLED RELEASE. 144(1). p.65-74
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- Journal Article
- A1
Pegylation of liposomes favours the endosornal degradation of the delivered phosphodiester oligonucleotides

Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2007) JOURNAL OF CONTROLLED RELEASE. 117(2). p.256-266
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- Journal Article
- A1
Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples

Kevin Braeckmans (UGent) , Katrien Remaut (UGent) , Roosmarijn Vandenbroucke (UGent) , Bart Lucas (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2007) BIOPHYSICAL JOURNAL. 92(6). p.2172-2183
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- Journal Article
- A1
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine

Katrien Remaut (UGent) , Bart Lucas (UGent) , Koen Raemdonck (UGent) , Kevin Braeckmans (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2007) BIOMACROMOLECULES. 8(4). p.1333-1340
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- A1
Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy?

Katrien Remaut (UGent) , Bart Lucas (UGent) , Koen Raemdonck (UGent) , Kevin Braeckmans (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2007) JOURNAL OF CONTROLLED RELEASE. 121(1-2). p.49-63
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- Journal Article
- A1
Nucleic acid delivery: Where material sciences and bio-sciences meet

Katrien Remaut (UGent) , Niek Sanders (UGent) , Bruno De Geest (UGent) , Kevin Braeckmans (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2007) MATERIALS SCIENCE & ENGINEERING R-REPORTS. 58. p.117-161
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- PhD Thesis
- open access
Exploring the relation between the intracellular fate and biological activity of nucleic acid nanoparticles

Katrien Remaut (UGent)

(2007)
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- Journal Article
- A1
Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation- a case study for fluorescein

Kevin Braeckmans (UGent) , Barbara Stubbe, Katrien Remaut (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2006) JOURNAL OF BIOMEDICAL OPTICS. 11(4).
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- A1
In situ analysis of single-stranded and duplex siRNA integrity in living cells

Koen Raemdonck (UGent) , Katrien Remaut (UGent) , Bart Lucas (UGent) , Niek Sanders (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2006) BIOCHEMISTRY. 45(35). p.10614-10623
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- A1
Characterization of the mode of incorporation of lipophilic compounds in solid dispersions at the nanoscale using fluorescence resonance energy transfer (FRET)

DJ VAN DROOGE, Kevin Braeckmans (UGent) , WLJ HINRICHS, Katrien Remaut (UGent) , Stefaan De Smedt (UGent) and HW FRIJLINK

(2006) MACROMOLECULAR RAPID COMMUNICATIONS. 27(14). p.1149-1155
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- A1
Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick?

Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Niek Sanders (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2006) BIOCHEMISTRY. 45(6). p.1755-1764
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Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes

Katrien Remaut (UGent) , Niek Sanders (UGent) , Farzaneh Fayazpour (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2006) JOURNAL OF CONTROLLED RELEASE. 115(3). p.335-343
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Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells

Bart Lucas (UGent) , Katrien Remaut (UGent) , Niek Sanders (UGent) , Kevin Braeckmans (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2005) JOURNAL OF CONTROLLED RELEASE. 103(2). p.435-450
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- Conference Paper
- C3
Fluorescence energy transfer to study the degradation of double-labeled oligonucleotides

Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Niek Sanders (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2005) JOURNAL OF CONTROLLED RELEASE. 101(1-3). p.352-354
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FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery

Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Niek Sanders (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2005) JOURNAL OF CONTROLLED RELEASE. 103(1). p.259-271
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Studying biophysical barriers to DNA delivery by advanced light microscopy

Stefaan De Smedt (UGent) , Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Niek Sanders (UGent) and Jo Demeester (UGent)

(2005) ADVANCED DRUG DELIVERY REVIEWS. 57(1). p.191-210
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Protection of oligonucleotides against nucleases by pegylated and non-pegylated liposomes as studied by fluorescence correlation spectroscopy

Katrien Remaut (UGent) , Bart Lucas (UGent) , Kevin Braeckmans (UGent) , Niek Sanders (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)

(2005) JOURNAL OF CONTROLLED RELEASE. 110(1). p.212-226
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Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fluorescence fluctuation spectroscopy and confocal imaging

Bart Lucas (UGent) , Katrien Remaut (UGent) , Niek Sanders (UGent) , Kevin Braeckmans (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2005) BIOCHEMISTRY. 44(29). p.9905-9912
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- Conference Paper
- C3
123I-EGF internalisation in tumour cells in vitro is inhibited by farnesyltransferase inhibitor therapy: possible target for early therapy response prediction

Bart Cornelissen, Katrien Remaut (UGent) , Veerle Kersemans, Ruth Oltenfreiter (UGent) , Ingrid Burvenich and Guido Slegers (UGent)

(2004) EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 31(suppl. 2). p.S391-S391
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On the biological activity of anti-ICAM-1 oligonucleotides complexed to non-viral carriers

Bart Lucas (UGent) , Elsa Van Rompaey, Katrien Remaut (UGent) , Niek Sanders (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2004) JOURNAL OF CONTROLLED RELEASE. 96(1). p.207-219
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Studying pegylated DNA complexes by dual color fluorescence fluctuation spectroscopy

Bart Lucas (UGent) , Katrien Remaut (UGent) , Kevin Braeckmans (UGent) , Jurgen Haustraete (UGent) , Stefaan De Smedt (UGent) and Jo Demeester (UGent)

(2004) MACROMOLECULES. 37(10). p.3832-3840

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

Materials and technologies to combat counterfeiting of pharmaceuticals : current and future problem tackling

Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

Electrostatic precipitation is a valuable adjunct to pressurized intraperitoneal aerosol chemotherapy : an in vitro study

Local release of siRNA using polyplex-loaded thermosensitive hydrogels

Electrostatic intraperitoneal aerosol delivery of nanoparticles : proof of concept and preclinical validation

Intraperitoneal aerosolized drug delivery : technology, recent developments, and future outlook

Influence of pathogenic stimuli on Müller cell transfection by lipoplexes

Fluorescence-based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts

Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine : cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate peritoneal metastasis of advanced human ovarian cancer

High pressure nebulization (PIPAC) versus injection for the intraperitoneal administration of mRNA complexes

Photoablation of human vitreous opacities by light-induced vapor nanobubbles

Non-viral delivery of chemically modified mRNA to the retina : subretinal versus intravitreal administration

Aerosolization of nanotherapeutics as a newly emerging treatment regimen for peritoneal carcinomatosis

The obstacle course to the inner retina : hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane

Establishment of a rat ovarian peritoneal metastasis model to study pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Morphology and composition of the inner limiting membrane : species-specific variations and relevance toward drug delivery research

Müller cells as a target for retinal therapy

Fluorescence correlation spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes

Search for the source of the retinal relaxing factor

Towards the development of a RNAi-based topical treatment for psoriasis : proof-of-concept in a 3D psoriasis skin model

Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles

Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy

The proton sponge hypothesis : fable or fact?

Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles

Technical implementations of light sheet microscopy

Quantifying the average number of nucleic acid therapeutics per nanocarrier by single particle tracking microscopy

In vitro and ex vivo models to study drug delivery barriers in the posterior segment of the eye

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Microfabricated devices for single objective single plane illumination microscopy (SoSPIM)

Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis : mission possible?

Coating of quantum dots strongly defines their effect on lysosomal health and autophagy

PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy

Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy

High-pressure nebulization as application route for the peritoneal administration of siRNA complexes

Toward smart design of retinal drug carriers : a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies

Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA

Approximate Bayesian computation for estimating number concentrations of monodisperse nanoparticles in suspension by optical microscopy

Evading innate immunity in nonviral mRNA delivery : don't shoot the messenger

Aerosolized non-viral nucleic acid delivery in the vaginal tract of pigs

Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Targeted decationized polyplexes for siRNA delivery

Intraperitoneal nonviral nucleic acid delivery in the treatment of peritoneal cancer

Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori

Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery

Intracellular delivery of nanomaterials: how to catch endosomal escape in the act

Cell division responsive peptides for optimized plasmid DNA delivery : the mitotic window of opportunity?

Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Effect of covalent fluorescence labeling of plasmid DNA on its intracellular processing and transfection with lipid-based carriers

Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy

Noncoding DNA in lipofection of HeLa cells: a few insights

Measuring the intravitreal mobility of nanomedicines with single-particle tracking microscopy

Correlation of dual colour single particle trajectories for improved detection and analysis of interactions in living cells

Efficient transfection of hepatocytes mediated by mRNA complexed to galactosylated cyclodextrins

Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis

Matrix systems for siRNA delivery

An ex vivo assay to measure the mobility inside the eye of nanomedicines for retinal gene therapy

Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles

Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles

PEGylation of biodegradable dextran nanogels for siRNA delivery

Efficient delivery of intact phosphodiester oligonucleotides by poly-β-amino esters

Pegylation of liposomes favours the endosornal degradation of the delivered phosphodiester oligonucleotides

Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples

Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine

Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy?

Nucleic acid delivery: Where material sciences and bio-sciences meet

Exploring the relation between the intracellular fate and biological activity of nucleic acid nanoparticles

Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation- a case study for fluorescein

In situ analysis of single-stranded and duplex siRNA integrity in living cells

Characterization of the mode of incorporation of lipophilic compounds in solid dispersions at the nanoscale using fluorescence resonance energy transfer (FRET)

Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick?

Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes

Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells

Fluorescence energy transfer to study the degradation of double-labeled oligonucleotides