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Coaching doctors to improve ethical decision-making in adult hospitalized patients potentially receiving excessive treatment : process evaluation study of the CODE intervention in doctors and nurses working in ten acute hospital wards
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- Journal Article
- A1
- open access
Be-SNAP : the Belgian Sepsis National Action Plan
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- Miscellaneous
- open access
Coaching doctors to improve ethical decision-making in adult hospitalized patients potentially receiving excessive treatment : the CODE stepped-wedge cluster randomized controlled trial (vol 50, pg 1635, 2024)
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- Journal Article
- A1
- open access
The use of information technology to improve interdisciplinary communication during infectious diseases ward rounds on the paediatric intensive care unit
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Big breaths for small lungs : clinician oversight or compensation for dead space?
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When should I start broad-spectrum antibiotics?
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Development and validation of a survey to assess self-reported knowledge of junior physicians in antimicrobial prescribing and stewardship
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Selective decontamination of the digestive tract : it's all in your mind!
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- Journal Article
- A1
- open access
Coaching doctors to improve ethical decision-making in adult hospitalized patients potentially receiving excessive treatment : the CODE stepped-wedge cluster randomized controlled trial
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- Journal Article
- A1
- open access
Ferroptosis and pyroptosis signatures in critical COVID-19 patients
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- Journal Article
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In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations : a retrospective observational study
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- Journal Article
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- open access
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
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Video-assisted thoracic surgery in critically ill COVID-19 patients on venovenous extracorporeal membrane oxygenation
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- Journal Article
- A1
- open access
Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients : a prospective single center observational study
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Selective digestive decontamination-Pro
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- Journal Article
- A1
- open access
Discussions on VT4COVID
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- Journal Article
- A1
- open access
Tight blood-glucose control without early parenteral nutrition in the ICU
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A breath of relief : navigating the resolution of unexplained respiratory failure
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- Journal Article
- A1
- open access
Healthcare-associated infections in adult intensive care unit patients : changes in epidemiology, diagnosis, prevention and contributions of new technologies
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Foxglove poisoning : diagnostic and therapeutic differences with medicinal digitalis glycosides overdose
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Antimicrobial prescription in severe COVID-19 and CAP : a matched case-control study
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- Journal Article
- A1
- open access
Case report : hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis
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- Journal Article
- A1
- open access
Adult essential extracorporeal membrane oxygenation (ECMO) skills for use in an e-learning program for ICU physicians, nurses and perfusionists : a consensus by a modified Delphi questionnaire
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Empirical antimicrobial use in ICU and outcome before and after abandoning the concept of healthcare-associated pneumonia : a single center retrospective analysis
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- Journal Article
- A1
- open access
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
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Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19 : a randomized clinical trial
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- Journal Article
- A1
- open access
Prospective longitudinal evaluation of hospitalised COVID-19 survivors 3 and 12 months after discharge
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- Journal Article
- A2
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Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients
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Delayed presentation of acute stroke patients in a Belgian stroke center during the first COVID-19 wave
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Outcome and characteristics of patients presenting to the emergency department with respiratory symptoms during the first COVID-19 wave
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A retrospective validation of COVID-19 referral criteria to the emergency department
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- Journal Article
- A1
- open access
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial
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Optimizing the use of antibiotic agents in the pediatric intensive care unit : a narrative review
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Posaconazole for prevention of invasive pulmonary aspergillosis in critically ill influenza patients (POSA-FLU) : a randomised, open-label, proof-of-concept trial
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- Journal Article
- A1
- open access
Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis
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- Journal Article
- A1
- open access
Outcomes of ICU patients with and without perceptions of excessive care : a comparison between cancer and non-cancer patients
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- Journal Article
- A1
- open access
Characteristics of Sepsis-2 septic shock patients failing to satisfy the Sepsis-3 septic shock definition : an analysis of real-time collected data
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Adult-onset congenital central hypoventilation syndrome due to PHOX2B mutation
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- Journal Article
- A1
- open access
Conceptions of the pathophysiology of happy hypoxemia in COVID-19
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- Journal Article
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- open access
Triage policy of severe Covid-19 patients : what to do now?
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Pharmacokinetics and target attainment of intravenous posaconazole in critically ill patients during extracorporeal membrane oxygenation
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- Journal Article
- A1
- open access
Attributable mortality of ventilator-associated pneumonia : replicating findings, revisiting methods
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Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial
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- Journal Article
- A1
- open access
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study
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- Journal Article
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- open access
Haemoptysis as the first presentation of COVID-19 : a case report
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- Journal Article
- A1
- open access
Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19
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- Journal Article
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- open access
The pathophysiology of 'happy' hypoxemia in COVID-19
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- Journal Article
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- open access
Epidemiology of Pneumocystis jirovecii pneumonia and (non-)use of prophylaxis
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Automated screening of natural language in electronic health records for the diagnosis septic shock is feasible and outperforms an approach based on explicit administrative codes
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- Journal Article
- A1
- open access
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients : a randomized clinical trial
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Antimicrobial de-escalation in critically ill patients : a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)
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- Journal Article
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- open access
Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition : an expert opinion
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Outcome after surgical procedures in adult home ventilated patients at Ghent University Hospital : a registry study
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Guideline on the prudent prescription of antibiotics in the dental office
(2020) KCE REPORTS. -
Benign gastrobronchial fistula following oesophagectomy in a patient presenting with respiratory failure
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- Journal Article
- A2
- open access
Meningitis in a patient with neutropenia due to Rothia mucilaginosa : a case report
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Outcomes of patients presenting with mild acute respiratory distress syndrome : insights from the LUNG SAFE study
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Changes in critically ill cancer patients’ short-term outcome over the last decades : results of systematic review with meta-analysis on individual data
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A practical approach to clinical antibiotic stewardship in the ICU patient with severe infection
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Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion
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Optimal and responsible use of antibiotics
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What happens after ICU discharge? : a within-hospital seamless care analysis of antimicrobial therapy
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- Journal Article
- A1
- open access
Influence of neutropenia on mortality of critically ill cancer patients : results of a meta-analysis on individual data
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Beat around the bush for VA-LRTI
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Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza : a retrospective cohort study
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Decontamination strategies and bloodstream infections with antibiotic-resistant microorganisms in ventilated patients : a randomized clinical trial
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Emergence of antimicrobial resistance to piperacillin/tazobactam or meropenem in the ICU : intermittent versus continuous infusion : a retrospective cohort study
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Anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease : a case report
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- Journal Article
- A1
- open access
A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit : results from a prospective four-year registration
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Impact of AST meetings on antimicrobial therapy decisions in the ICU
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Staphylococcus aureus colonization at ICU admission as a risk factor for developing S. aureus ICU pneumonia
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The Intensive Care Medicine research agenda on critically ill oncology and hematology patients
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- Journal Article
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- open access
Low flow extracorporeal CO2 removal in ARDS patients : a prospective short-term crossover pilot study
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- Journal Article
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- open access
P. aeruginosa colonization at ICU admission as a risk factor for developing P. aeruginosa ICU pneumonia
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Noninvasive mechanical ventilation in critically ill patients with hematological malignancy : flow chart, evidence, and key practical recommendations
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Antibiotic stewardship : do not rely on de-escalation alone
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- Journal Article
- A1
- open access
Oral mucosal adverse events with chlorhexidine 2 % mouthwash in ICU
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Prone position acute respiratory distress syndrome patients : less prone to ventilator associated pneumonia?
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- Journal Article
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- open access
Long-term outcome and health-related quality of life in difficult-to-wean patients with and without ventilator dependency at ICU discharge : a retrospective cohort study
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Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study
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- Journal Article
- A1
- open access
Disulfiram inhibition of cyanide formation after acetonitrile poisoning
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Reducing antibiotic use in the ICU : a time-based approach to rational antimicrobial use
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Farmacotherapeutische actualiteit
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The ten 'diseases' that are not true diseases
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Farmacotherapeutische actualiteit
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Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis
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Protease production by Staphylococcus epidermidis and its effect on Staphylococcus aureus biofilms
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Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
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Validity analysis of a unique infection surveillance system in the intensive care unit by analysis of a data warehouse built through a workflow-integrated software application
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- Journal Article
- A1
- open access
Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit : a retrospective analysis
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- Journal Article
- A2
- open access
Noninvasive mechanical ventilation in high-risk pulmonary infections: a clinical review
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- Journal Article
- A2
- open access
Dual disseminated infection with Nocardia farcinica and Mucor in a patient with systemic lupus erythematosus : a case report
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Disulfiram inhibition of cyanide formation after acetonitrile poisoning
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- Journal Article
- A1
- open access
Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?
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A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals.
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Factors associated with inadequate early vancomycin levels in critically ill patients treated with continuous infusion
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- Journal Article
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- open access
The presence of antibiotic-resistant nosocomial pathogens in endotracheal tube biofilms and corresponding surveillance cultures
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Microbial etiology and antimicrobial resistance in healthcare-associated versus community-acquired and hospital-acquired bloodstream infection in a tertiary care hospital
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Long-term outcomes and quality of life in critically ill patients with hematological or solid malignancies: a single center study
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Diagnostic potential of open lung biopsy in mechanically ventilated patients with diffuse pulmonary infiltrates of unclear aetiology
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COSARA: integrated service platform for infection surveillance and antibiotic management in the ICU
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Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT international cohort study
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Fatal acute pulmonary injury associated with everolimus
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TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial
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Early recognition of malignant lactic acidosis in clinical practice: report on 6 patients with haematological malignancies
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- Journal Article
- A1
- open access
Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches
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- Conference Paper
- C3
- open access
Prevalence of perceptions of inappropriate care among intensive care unit healthcare providers and reasons why disproportional care is continued : the APPROPRICUS study
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Attributable mortality of ventilator associated pneumonia: a reappraisal using causal analysis
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Outcome in critically ill patients with allogeneic BM or peripheral haematopoietic SCT : a single-centre experience
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Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians
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Open lung biopsy in patients with acute respiratory failure and bilateral pulmonary infiltrates
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Nursing home residence is the main risk factor for increased mortality in healthcare-associated pneumonia
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- Journal Article
- A1
- open access
Use of web services for computerized medical decision support, including infection control and antibiotic management, in the intensive care unit
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Non-invasive ventilation in patients with hematological malignancies: the saga continues, but where is the finale?
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- Journal Article
- A2
- open access
Severe drug-induced liver injury associated with prolonged use of Linezolid
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- Conference Paper
- C3
- open access
Preliminary results from the APPROPRICUS study (APPROPRIATENESS of CARE in the ICUs)
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Impact of organ dysfunction on mortality in ICU patients with hematologic malignancies
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Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis?
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The impact of the initial ventilatory strategy on survival in hematological patients with acute hypoxemic respiratory failure
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De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?
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Mechanical ventilation in cancer patients : clinical characteristics and outcomes
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EVOLUTION IN COAGULATION PARAMETERS OVER THE FIRST 3 DAYS OF ICU ADMISSION IN SEPTIC SHOCK PATIENTS: IMPACT ON 30 DAY MORTALITY
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ADMINISTRATION OF VANCOMYCIN USING A STANDARDIZED PROTOCOL: DO WE ACHIEVE THERAPEUTIC SERUM CONCENTRATION IN THE INITIAL PHASE IN CRITICALLY ILL PATIENTS?
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Trombotische microangiopathie als eerste teken van gemetastaseerd borstcarcinoom
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Preventie van nosocomiale pneumonie: antibioticastrategieën bij mechanisch geventileerde patiënten
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Design of software services for computer-based infection control and antibiotic management in the intensive care unit
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Bacteremia in patients with febrile neutropenia following chemotherapy
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Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies
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Daily cost of antimicrobial therapy in patients with Intensive Care Unit-acquired, laboratory-confirmed bloodstream infection
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Systematic surveillance cultures as a tool to predict involvement of multidrug antibiotic resistant bacteria in ventilator-associated pneumonia
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Maximizing rates of empiric appropriate antibiotic therapy with minimized use of broad-spectrum agents: are surveillance cultures the key?
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Temocillin: a valid option for directed therapy in ICU patients?
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- Journal Article
- A1
- open access
Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia
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- Journal Article
- A1
- open access
Support Vector machine versus logistic regression modeling for prediction of hospital mortality in critically ill patients with haematological malignancies
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Risk factors and outcome in ventilator-associated pneumonia
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Predictive value of surveillance cultures and subsequent bacteremia with extended-spectrum beta-lactamase-producing Enterobacteriaceae
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Polyurethane cuffed endotracheal tubes to prevent early postoperative pneumonia after cardiac surgery: A pilot study
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Improving the adequacy of empirical beta-lactam therapy for Pseudomonas aeruginosa ventilator-associated pneumonia
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Measuring the impact of multidrug resistance in nosocomial infection
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Comment on: Impact of antibiotic resistance and of adequate empirical antibiotic treatment in the prognosis of patients with Escherichia coli bacteraemia
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Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: a historical cohort study
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Tracheotomy: clinical review and guidelines
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Antibiotic therapy for ventilator-associated pneumonia: De-escalation in the real world
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Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
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Antibiotic therapy for community-acquired pneumonia with septic shock: Follow the guidelines
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Nosocomiale pneumonie buiten het ziekenhuis: 'health-care associated pneumonia' en rusthuispneumonie
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Multidrug resistant pathogens in bacterial infections acquired at the intensive care unit and the contribution of surveillance cultures to early appropriate antibiotic therapy
(2007) -
Microbial surveillance in the intensive care unit
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Community-acquired versus nosocomial Klebsiella pneumonia bacteremia: Clinical features, treatment outcomes, and clinical implication of antimicrobial resistance
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Dynamics of C-reactive protein in critically ill patients with nosocomial gram-positive versus gram-negative bacteremia
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Effects of selection of control subjects in a case-control study on the outcome of catheter-related bloodstream infection - Reply to Rijnders
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Poly-urethane cuffed versus conventional endotracheal tube in the prevention of early postoperative pneumonia in cardiac surgery patients: a randomized trial
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- Conference Paper
- C1
- open access
Value of poly-urethane cuffed endotracheal tube in the prevention of early post-operative pneumonia
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Nosocomial pneumonia: aetiology, diagnosis and treatment
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Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients
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Outcome in severely ill patients with hematological malignancies who received intravenous chemotherapy in the intensive care unit
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Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit
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Outcome in bacteremia associated with nosocomial pneumonia and the impact of pathogen prediction by tracheal surveillance cultures
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Ventilator-associated pneumonia in a tertiary care ICU: Analysis of risk factors for acquisition and mortality
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Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections
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Colonization status and appropriate antibiotic therapy for nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in an intensive care unit
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Would patients with more subtle signs of coagulopathy have benefited from treatment with activated protein C?
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Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome
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Outcome in critically ill medical patients treated with renal replacement therapy for acute renal failure: comparison between patients with and those without haematological malignancies
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Antibiotic therapy and outcome in critically ill patients with pneumococcal bacteremia
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Influence of matching for exposure time on estimates of attributable mortality caused by nosocomial bacteremia in critically ill patients
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Invasive aspergillosis in critically ill patients: Analysis of risk factors for acquisition and mortality
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Outcome in noninvasively and invasively ventilated hematologic patients with acute respiratory failure
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Artificial neural networks in predicting outcome of gastrointestinal haemorrhage
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Bacterial infection
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Invasive aspergillosis in ICU patients: Analysis for risk factors and mortality
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Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells.
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Outcome in critically ill hematologic cancer patients : impact of bacterial infection