Show
Sort by
-
5-HT2A Receptors in the feline brain: 123I-5-I-R91150 kinetics and the influence of ketamine measured with micro-SPECT
-
Ketamine decreases the cerebral binding index of the selective 5-HT2A receptor radioligand 123I-R91150 measured with µSPECT in cats
-
The influence of ketamine on the regional cerebral perfusion and on the binding index of the selective 5-HT2A receptor radioligand 123I-R91150 measured with SPECT in the canine brain
-
99mTc-DMSA absolute and relative renal uptake in cats: procedure and normal values
-
- Journal Article
- A1
- open access
Nuclear medicine: investigation of renal function in small animal medicine
-
Recognition of anatomical predilection sites in canine elbow pathology on bone scans using micro-single photon emission tomography
-
Ultrasound prediction of the partus datum in dogs
-
Determination of optimal sampling times for a two blood sample clearance method using 51Cr-EDTA in cats
-
How to reach compliance for manufacturing of PET-radiopharmaceuticals under current EU-GMP regulations: an approach for University Hospitals
-
LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin
-
The use of [I-123]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: In vitro R1M rabdomyosarcoma cell and in vivo mouse experiments
-
In vitro and in vivo evaluation of direct rhenium-188-labeled anti-CD52 monoclonal antibody alemtuzumab for radioimmunotherapy of B-cell chronic lymphocytic leukemia
-
Monoclonal antibody 14C5 targets integrin alpha(v)beta(3)
-
Annexin V detection of lipopolysaccharide-induced cardiac apoptosis
-
Differences of cortical 5-HT2A receptor binding index with SPECT in subtypes of anorexia nervosa: Relationship with personality traits?
-
Assessment of the solid-state composition of an active salicylanilide compound by FT-Raman spectroscopy
-
Comparison of the wetting properties of three commonly used simulated intestinal fluids used as dissolution media in the characterization of drugs
-
Stability of the OECD model compound benzoic acid in receptor fluids of Franz diffusion cells
-
Biodistribution and planar gamma camera imaging of I-123- and I-131-labeled F(ab ')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor
-
Analysis of iodinated peptides by LC-DAD/ESI ion trap mass spectrometry
(2007) JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 850(1-2). p.213-220 -
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds
-
Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma
-
Sequential Tc-99m-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy
-
Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma
-
Influence of sedation and data acquisition method on tracer uptake in animal models: [I-123]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice
-
Comparative biodistribution study of the new tumor tracer [I-123]-2-iodo-L-phenylalanine with [I-123]-2-iodo-L-tyrosine
-
Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.
-
I-123/125-labelled 2-iodo-L-phenylalanine and 2-iodo-D-phenylalanine: comparative uptake in various tumour types and biodistribution in mice
-
Synthesis and HPLC-purification of [Br-77]TMC125-R165335 (etravirine), a new anti-HIV drug of the DAPY-NNRTI class
-
Characterisation of a preservative system in an oily preparation
-
Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents
-
Influence of deposition and spray pattern of nasal powders on insulin bioavailability
-
Stoichiometry of complexes by quantifying qualitative UV-VIS spectroscopic shifts
-
- Conference Paper
- C1
- open access
Analytical characterisation of arsenic anticoccidials and their determination in poultry feed
-
The importance of the cosolvent propylene glycol on the antimicrobial preservative efficacy of a pharmaceutical formulation by DOE-ruggedness testing
-
In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy
-
Small animal positron emission tomography during vagus nerve stimulation in rats: A pilot study
-
In vivo evaluation of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-benzamide: a potential sigma receptor ligand for SPECT studies
-
In vivo evaluation of [I-123]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno [3,4-c]pyridin-5-one: a presumed dopamine D-4 receptor ligand for SPECT studies
-
Comparison between 1 T MRI and non-MRI based volumetry in inoculated tumours in mice
-
Synthesis, quality control and in vivo evaluation of [I-123] rhTIMP-2, a potential tumour-imaging agent
-
Mass uniformity: Influence of operational compression conditions on breakability of scored tablets as part of manufacturing robustness evaluation
-
Synthesis, radiosynthesis and in vivo evaluation in mice of [I-123]-(4-fluorophenyl) {1-[2-(4-iodophenyl)ethyl]piperidin-4-yl}methanone for visualization of the 5-HT2A receptor with SPECT
-
Imaging of the seroton transporter before and after citalopram administration in canine brain with 123I-betaCIT SPECT
-
Synthesis of [I-123]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno[3,4-c]pyri din-5-one, a potential dopamine D4 ligand for SPECT studies
-
Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of Tc-99m labelled epidermal growth factor
-
Synthesis, radiosynthesis, in vitro and preliminary in vivo evaluation of biphenyl carboxylic and hydroxamic matrix metalloproteinase (MMP) inhibitors as potential tumor imaging agents
-
Tryptophane-based biphenylsulfonamide matrix metalloproteinase inhibitors as tumor imaging agents
-
Determination of the relative amounts of three crystal forms of a benzimidazole drug in complex finished formulations by FT-Raman spectroscopy
-
In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model
-
In vivo evaluation and dosimetry of I-123-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT in an R1M rhabdomyrosarcoma athymic mouse model
-
Synthesis, radiosynthesis and preliminary in vivo evaluation of [I-123](4-fluorophenyl) {1-[2-(2(2-iodophenyl)ethyl]piperidin-4-yl}methanone, a potential 5-HT2A-antagonist for SPECT brain imaging
-
Radiolabeling, biodistribution, and dosimetry of I-123-mAb 14C5: A new mAb for radioimmunodetection of tumor growth and metastasis in vivo
-
Improved targeting with F(ab)2 fragments of monoclonal antibody 14C5 for imaging and therapy of metastatic disease
-
Micro-pet during vagus nerve stimulation in rats: A pilot study
-
Synthesis, radiosynthesis and preliminary in vivo evaluation of [123I]-(1-(5-iodo-2-methoxyphenethyl)piperidin-4-yl)(4-fluorophenyl)methanone as a potential SPECT tracer for visualizing the 5-HT2A-receptor
-
123I-labelled monoclonal antibody 14C5 for SPECT tumour imaging: In vivo evaluation of athymic mice bearing a LoVo tumour
-
Targeting properties of radiolabelled monoclonal antibody 14c5 directed against a cell substrate adhesion molecule
-
In vitro evaluatie van 14C5 monoklonaal antilichaamderivaten voor gebruik in radioimmunodiagnostiek en radioimmunotherapie
-
Synthese van de precursor, radiosynthese en in vivo evaluatie in muizen van [123I]-(4-fluorofenyl){1-[2-(4-iodofenyl)ethyl]piperidin-4-yl}methanon, als potentiële SPECT ligand voor de 5-HT2A-receptor
-
Relationship of Tc-99m-HYNIC annexin V uptake to microvessel density, FasL and MMP-9 expression, and the number of tumour-infiltrating lymphocytes in head and neck carcinoma
-
Internalization and cellular processing of radiolabeled monoclonal antibody 14C5
-
Radiosynthesis and in vivo evaluation of a carboxylic MMP inhibitor as potential SPECT tumour imaging agent
-
123I-EGF internalisation in tumour cells in vitro is inhibited by farnesyltransferase inhibitor therapy: possible target for early therapy response prediction
-
Radiosynthesis and in vivo evaluation of 123I-rTIMP-2 as potential SPECT tumour imaging agent
-
Development, pharmaceutical validation and radioprotection properties of a new concept of 188W/188Re generator
-
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents
-
Functional brain imaging and large animal research
-
Synthesis and assessment of [C-11]acetylhomotaurine as an imaging agent for the study of the pharmacodynamic properties of acamprosate by positron emission tomography
-
Tc-99m-HYNIC Annexin-V imaging of primary head and neck carcinoma
-
- Conference Paper
- C3
- open access
Imaging of the serotonin transporter before and after citalopram administration in canine brain with 123I-betaCIT SPECT
-
Comparison of cortical 5-HT2A receptor binding in bulimia nervosa patients and healthy volunteers
-
Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study
-
Precursor synthesis, radiosynthesis and in vivo evaluation in mice of [I-123]-(4-fluorophenyl) {1-[2-(2-iodophenyl)ethyl]piperidin-4-yl}-methanone and -methanol, as potential SPECT tracers for the 5-HT2A-receptor
-
Synthesis and preliminary in vivo evaluation of [18F] labelled derivatives of Org 13063 as potential PET radioligands for the 5-HT1A receptor
-
Screening for supra-additive effects of cytotoxic drugs and gamma irradiation in an in vitro model for hepatocellular carcinoma
-
In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: Relative biological efficacy with respect to apoptosis induction and chromosomal damage by the micronucleus assay
-
Cold and alpha-conjugated anti-CD20 induce different in vitro apoptosis reponses in B-chronic lymphocytic leukaemia (B-CLL)and splenic lymphoma with villous lymphocytes (SLVL)
-
Alpha-immunotherapy compared to external gamma irradiation, cold antibody and chemotherapy in B-CLL in vitro: Correlation with clinical chemotherapy sensitivity
-
Cytotoxicity of gamma versus alpha radiation in lymphoid cell lines with defects in the TNF receptor family mediated and NF-kappa B related apoptotic and anti-apoptotic pathways
-
Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide
-
Regional cerebral bloodflow and binding index of the 5-Ht2A receptor in the impulsive aggressive dog treated with citalopram
-
Evaluation of the aging brain with single photon emission tomography
-
Physico-chemical screening tests using IV2SOL technology in the development of liquid pharmaceutical formulations
-
Investigation of preservative systems by experimental design: drug product optimisation and robustness characterisation
-
Radiosynthesis and biological activity testing of a potent gelatinase inhibitor, a new potential SPECT tumour imaging agent
-
Synthesis and in vivo evaluation in mice and rabbits of [123I]-3-(4-iodobenzyl)-8-methoxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one as possible agent for imaging of the dopamine D4-receptor
-
Biodistribution og 123/125I-VEGF in wild type NMRI and A2058 tumor inoculated athymic mice
-
Synthesis and in vivo evaluation of [123I]-pyrimidine-Org 13063 as potential SPECT radioligand for the 5-HT1A receptor
-
In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage
-
Quantitative tumor apoptosis imaging using technetium-99m-HYNIC annexin V single photon emission computed tomography
-
Imaging of microglial activation with PET and atrophy with MRI in multiple sclerosis : interrelationship and clinical correlates
-
PET visualization of microglia in multiple sclerosis patients using [C-11]PK11195
-
Imaging of the 5-HT2A system: age-, gender-, and Alzheimer's disease-related findings
-
Nuclear medicine imaging to predict response to radiotherapy: A review
-
Decreased 5-HT2a receptor binding in patients with anorexia nervosa
-
Synthesis and radiolabelling of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D-3 antagonist for SPECT studies
-
Synthesis and radiolabelling of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D-3 antagonist for SPECT studies
-
Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150
-
Evaluation of cerebral neurotransmitter physiology and pathophysiology with PET and SPET imaging modalities in animal models
-
Regional binding index of the radiolabeled selective 5-ht2a antagonist 123I-5-1-r91150 in the normal canine brain imaged with single photon emission computed tomography
-
Anti-microbial preservatives in oily preparations
-
Assessment of neuroinflammation and microglial activation in Alzheimer’s disease with radiolabelled PK11195 and single photon emission computed tomography : a pilot study
-
Alpha-immunotherapy compared to gamma-radiation, cold antibody, and chemotherapy in B-CLL in vitro: Correlation with clinical chemosensitivity
-
Biological activity determination of I-BSP, a potent MMP 2 inhibitor, and its 123I tracer synthesis, World Journal of Nuclear Medicine, 2002, volume 1, supplement 2, S188
-
Synthesis and in vivo evaluation of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential sigma receptor ligand for SPECT studies
-
Toepassingen van de radionuclidentherapie: radiofarmaca, werkingsmechanismen en stralingsbescherming
-
Biodistribution and displacement studies of the selective 5-HT2A receptor antagonist I-123-5-I-R91150 in the normal dog.
-
Tumour angiogenesis pathways: related clinical issues and implications for nuclear medicine imaging.
-
Effects of aging on brain perfusion and serotonin-2A receptor binding in the normal canine brain measured with single photon emission tomography.
-
Semiquantification of the peripheral-type benzodiazepine ligand [C-11]PK11195 in normal human brain and application in multiple sclerosis patients
-
Statistical analysis of tablet breakability methods
-
Comparison of in vitro apoptosis induction by alpha-irradiation versus gamma-irradiation in B-CLL
-
Title: Synthesis, biodistribution and blocking studies in mice of a new 123I-labeled dopamine D3 antagonist Dierckx RA, Slegers G
-
Le système serotoninergique dans le comportement suicidaire
-
Differential regional cerebral uptake of F-18-fluoro-2-deoxy-D-glucose in Alzheimer's disease and frontotemporal dementia at initial diagnosis
-
57Co SPECT, 99mTc-ECD SPECT, MRI and neuropsychological testing in senile dementia of the Alzheimer type
-
In vivo evaluation of serotonin-2A receptors in normal canine brain: a SPECT study with a selective 5-HT2a receptor ligand labelled with 123I
-
Synthesis and evaluation of [I-123]iodoaminoglutethimide, a ligand for visualization of the aromatase enzyme by SPECT
-
The pharmacokinetics of [C-11]methoxy-norchloroprogabidic acid, a potential PET tracer for GABA receptors in the brain.
-
High-performance liquid chromatographic determination of [11C]1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide in mouse plasma and tissue and in human plasma
-
Biodistribution and dehalogenation studies of two radiohalogenated kynurenic acid derivatives, potent antagonists of the N-methyl-D-aspartate receptor
-
Determination of tritiated dexamethasone in rat liver and muscle: Comparison of two sample preparation techniques, combustion and solubilization, prior to liquid scintillation counting.
-
Biodistribution and dosimetry of carbon-11-methoxyprogabidic acid, a possible ligand for GABA-receptors in the brain.
-
Synthesis of [C-11] granisetron, a possible Positron Emission Tomography ligand for 5-HT3 receptor studies.
-
Synthesis and evaluation of 123I-iodoaminoglutethimide,a ligand for visualisation of the aromatase enzyme by SPECT
-
C-11-methoxyprogabidic acid, a possible ligand for GABA-receptors in the brain: Biodistribution, dosimetry, pharmacokinetics and preliminary results.
-
Radiolabelling optimisation of 7-bromo-5-[I-123]-iodo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid: A potential tracer for NMDA SPECT studies.
-
Synthesis and in vivo evaluation of 7-chloro-5-[I-123]iodo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid.
-
Synthesis of 123I-iodoaminogluthetimide,a possible radioligand for the visualisation of the aromatase enzyme in breast carcinoma by SPECT
-
Synthesis of 7-chloro-5-123I-iodokynurenic acid:a possible tracer for in vivo imaging of N-methyl-D-aspartate receptors
-
Synthesis of [C-11]-granisetron as a possible PET ligand for the 5-HT3 receptor
-
Synthesis of [Br-77] 5,7-dibromo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, a possible SPECT tracer for NMDA receptor studies.
-
Synthesis of (R)-1-(4-[C-11]-p-methoxyphenyl-4-phenyl-3-butenyl)-3-piperidinecarboxylic acid for positron emission tomography of the GABA uptake carrier.
-
PMN-leucocyten isolatie en merking met 99mTc-HMPAO: een standard operating protocol als onderdeel van een kwaliteitsproceduresysteem
-
Synthesis of E/Z-(R)-1-[4-(4-methoxyphenyl)-4-phenyl-3-butenyl]-3-peperidinecarboxylic acid.
-
High-performance liquid Chromatographie determination of (4(^C)methoxy-phenyl)- (5-fluoro-2-hydroxyphenyl)-methyleneaminobutyric acid and its benzophenone metabolite.
-
SYNTHESIS OF 7-BROMO-5-IODO-4-OXO-1,4-DIHYDROQUINOLINE-2-CARBOXYLIC ACID.
-
PRODUCTION AND PURIFICATION OF BR-77 SUITABLE FOR LABELING MONOCLONAL-ANTIBODIES USED IN TUMOR IMAGING.
-
The synthesis of 4-(4-[llC]methoxyphenyl)-(5-fluoro-2-hydroxyphenyl)-methylene-aminobutyric acid as a potential radioligand for the GABA receptor in the brain.
-
PREPARATION OF BR-77 LABELED PROTEINS USING BROMOPEROXIDASE.
-
Synthesis of 4-(5-fiuoro-2-hydroxyphenyl)-(4-(11C)methoxyphenyl)-methylene-aminobutyric acid
-
Synthesis of (J^BT)5, 7-dibromo-4-oxo-l,4-dihydroquinoline-2-carboxylic acid for PET studies of N-methyl-D-aspartate receptors
-
Preparation of Bromine-77 Labeled anti-hLAP Monoclonal Antibody using Bromoperoxidase
-
Synthesis of N(4^ JOmethoxyphenyW-phenyl-S-butenyl) 3-piperidine carboxylic acid for PET study of GABA reuptake system
-
Preparation of Bromine-77 Labeled anti-hPLAP Monoclonal Antibody and its F(ab)2 Fragment using Bromoperoxidase
-
Production of carrier-free ⁶⁶GA and labeling of antimyosin antibody for positron imaging of acute myocardial-infarction
-
Synthesis and radiopharmaceutical preparation of (ethylenediamine) (1-carbon-11-malonate) platinum(II) for PET studies
-
High-performance liquid chromatography of α-substituted acetic acid derivatives
-
Criterion for evaluation and optimization in thin-layer chromatography
-
Direct assay for phosphotransacetylase and acetyl-coenzyme a carboxylase by high-performance liquid chromatography
-
Microscale synthesis of nitrogen-13-labeled cisplatin
-
Rapid determination of malonic acid by ion-pair reversed-phase high-performance liquid chromatography
-
Kinetics of 13N-ammonia incorporation in human tumors
-
Quantitative analysis of cis-dichlorodiammineplatinum(II) by high-performance thin-layer chromatography
-
Production of 3-(p-(^^-)methoxyphenyl)-4-aminobutyric acid. J. Pharm. Belg., 1993, vol. 48, p. 128.
-
Produktion and purification of 77Br suitable for labeling monoclonal antibodies used in tumor imaging. Radiochim. Acta., 1994, nr. 65, pp. 223-226, 1 fig.
-
Synthesis of (^isQ-Carboplatin. Synthesis and applications of isotopically labelled compounds 1991, Elsevier, Amsterdam, 1992, pp. 630-635,4 fig., 2tabb.