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- Journal Article
- A1
- open access
Ym1 protein crystals promote type 2 immunity
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- Journal Article
- A1
- open access
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity
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- Journal Article
- A1
- open access
Chitinases and chitinase-like proteins in asthma
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- Journal Article
- A1
- open access
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice
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- Journal Article
- A1
- open access
Emerging paradigms in type 2 immunity
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Isolation of conventional murine lung dendritic cell subsets
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IRE1 beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model
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- Journal Article
- A1
- open access
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes
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- Journal Article
- A1
- open access
CCR2-and Flt3-dependent inflammatory conventional type 2 dendritic cells are necessary for the induction of adaptive immunity by the human vaccine adjuvant system AS01
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The basic immunology of asthma
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Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy
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- Journal Article
- A1
- open access
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
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Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**
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- Journal Article
- A1
- open access
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
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TAO-kinase 3 governs the terminal differentiation of conventional dendritic cells
(2020) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(49). p.31331-31342 -
Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection
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Rbm7 in structural cells : a NEAT way to control fibrosis
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- Miscellaneous
- open access
Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine
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TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization
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- Miscellaneous
- open access
Wnt and Hippo pathways in regulatory T cells : a NOTCH above in asthma
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- Journal Article
- A1
- open access
Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice
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- Journal Article
- A1
- open access
How a farming environment protects from atopy
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- Journal Article
- A1
- open access
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice
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- Journal Article
- A1
- open access
Professional and 'amateur' antigen-presenting cells in type 2 immunity
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Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells
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Protein crystallization promotes type 2 immunity and is reversible by antibody treatment
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The cytokines of asthma
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- Journal Article
- A1
- open access
Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF
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- Journal Article
- A1
- open access
IL-33trap is a novel IL-33-neutralizing biologic that inhibits allergic airway inflammation
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Antigen-presenting dendritic cells
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Role of NKp46⁺ natural killer cells in house dust mite-driven asthma
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TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma
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Isolation of conventional murine lung dendritic cell subsets
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- Journal Article
- A1
- open access
The hygiene hypothesis : immunological mechanisms of airway tolerance
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The emerging role of ADAM metalloproteinases in immunity
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Dendritic cells in inflammatory disease
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- Journal Article
- A1
- open access
A bispecific antibody strategy to target multiple type 2 cytokines in asthma
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- Journal Article
- A1
- open access
Osteopontin promotes protective antigenic tolerance against experimental allergic airway disease
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- Journal Article
- A1
- open access
Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march
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The generation and use of allergen-specific TCR transgenic animals
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- Journal Article
- A1
- open access
The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome
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House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting
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Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin
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A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes
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The immunology of the allergy epidemic and the hygiene hypothesis
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- Journal Article
- A1
- open access
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
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Myeloid cells in asthma
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Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10
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- Journal Article
- A1
- open access
Bacteria isolated from lung modulate asthma susceptibility in mice
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Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells
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Murine models of allergic asthma
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Dendritic cells and type 2 inflammation
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GATA1-deficient dendritic cells display impaired CCL21-dependent migration toward lymph nodes due to reduced levels of polysialic acid
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Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung
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- Journal Article
- A1
- open access
Early IL-1 signaling promotes iBALT induction after influenza virus infection
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- Journal Article
- A1
- open access
A20 deficiency in lung epithelial cells protects against influenza A virus infection
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- Journal Article
- A1
- open access
Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; project no: 261357; 2010-2015
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IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively
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Mouse models of asthma
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Van hygiënehypothese tot theorie
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Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
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Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
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Interleukin-21-producing CD4(+) T cells promote type 2 immunity to house dust mites
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Barrier epithelial cells and the control of type 2 immunity
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Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? : the MeDALL hypothesis
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Role of B cell-activating factor in chronic obstructive pulmonary disease
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- Journal Article
- A1
- open access
Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming
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The immunology of asthma
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Antigen-presenting dendritic cells
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Flow cytometric sexing of spider sperm reveals an equal sperm production ratio in a female-biased species
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- Journal Article
- A1
- open access
A20-Deficient mast cells exacerbate inflammatory responses in vivo
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Allergens and the airway epithelium response: gateway to allergic sensitization
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Dendritic cell and epithelial cell interactions at the origin of murine asthma
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The function of Fcγ receptors in dendritic cells and macrophages
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Innate immune cells to the help
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The multi-faceted role of allergen exposure to the local airway mucosa
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Short cigarette smoke exposure facilitates sensitisation and asthma development in mice
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- Journal Article
- A1
- open access
The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β
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Death at the airway epithelium in asthma
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Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections
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Cytokine targets in airway inflammation
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- Journal Article
- A1
- open access
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
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Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease
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Conventional and monocyte-derived CD11b⁺ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen
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- Miscellaneous
- open access
Asthma and coagulation
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Asthma: the importance of dysregulated barrier immunity
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Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension
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The airway epithelium in asthma
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Engineered 3D microporous gelatin scaffolds to study cell migration
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Tertiary lymphoid organs in infection and autoimmunity
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Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection
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- Journal Article
- A2
- open access
Cellular networks controlling Th2 polarization in allergy and immunity
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Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
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Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy
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Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor
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Lung dendritic cells in respiratory viral infection and asthma : from protection to immunopathology
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- Journal Article
- A1
- open access
Evidence for local dendritic cell activation in pulmonary sarcoidosis
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- Journal Article
- A1
- open access
TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways
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The neuropeptide calcitonin gene-related peptide affects allergic airway inflammation by modulating dendritic cell function
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Anti-inflammatory actions of phosphatidylinositol
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MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine
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Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses
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Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCs
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C-Kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension
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Novel anti-inflammatory drugs based on targeting lung dendritic cells and airway epithelial cells
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An unexpected role for uric Acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma
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The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity
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TNF driven activation of invariant NKT cells regulates combined gut and joint inflammation
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Studying the function of dendritic cells in mouse models of asthma
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Vegf regulates embryonic erythroid development through Gata1 modulation
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Origin and functional specializations of DC subsets in the lung
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- Journal Article
- A1
- open access
Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
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The role of dendritic and epithelial cells as master regulators of allergic airway inflammation
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Invariant natural killer T cells are natural regulators of murine spondylarthritis
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Selective control of SIRP-α-positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation
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A novel method for isolating dendritic cells from human bronchoalveolar lavage fluid
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Function of dendritic cell subsets in allergic disease
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Mechanism of action of clinically approved adjuvants
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House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
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Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation
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Biology of lung dendritic cells at the origin of asthma
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An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation
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Cholera toxin B suppresses allergic inflammation through induction of secretory IgA
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Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells
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The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen
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Immune Suppression Feature of Ursodeoxycholic Acid is DC-mediated as Measured in Eosinophilic Airway Inflammation Model
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Lung dendritic cells: targets for therapy in allergic disease
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Antigen-presenting dendritic cells
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Antigen‐presenting dendritic cells and macrophages
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Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
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Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma
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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
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Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection
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Gata1 regulates dendritic-cell development and survival
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Lung dendritic cell migration
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Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
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Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function
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Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
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Rôle des différentes populations de cellules dendritiques dans l'asthme allergique
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Dendritic cells in asthma
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Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation
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Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses
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Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function
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Dendritic cell subsets and immune regulation in the lung
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Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
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Differential capacity of CD8 alpha(+) or CD8 alpha(-) dendritic cell subsets to prime for eosinophilic airway inflammation in the T-helper type 2-prone milieu of the lung
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Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses
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Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma
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Antigen-presenting cells
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B cell differentiation and IgE synthesis
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Prostaglandin D-2 inhibits airway dentritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1
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Lipopolysaccharide-induced suppression of airway Th2 responses does not require IL-12 production by dendritic cells
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Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: Consequences for the immune response
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The other cells in asthma: dendritic cell and epithelial cell crosstalk
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Opinion - Taking our breath away: dendritic cells in the pathogenesis of asthma
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Monocyte-derived dendritic cells induce a house dust mite-specific Th2 allergic inflammation in the lung of humanized SCID mice: Involvement of CCR7
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Myeloid dendritic cells make it to the top